4.6 Article

Intracellular kynurenine promotes acetaldehyde accumulation, further inducing the apoptosis in soil beneficial fungi Trichoderma guizhouense NJAU4742 under acid stress

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biotechnology & Applied Microbiology

Evolutionary and reverse engineering to increase Saccharomyces cerevisiae tolerance to acetic acid, acidic pH, and high temperature

Prisciluis Caheri Salas-Navarrete et al.

Summary: This study used adaptive laboratory evolution (ALE) and whole-genome analysis to generate strains of Saccharomyces cerevisiae tolerant to high temperatures, acetic acid, and acidic pH. Through a year of evolution, two strains were selected, TAT12 and AT22, which were capable of growing and producing ethanol in conditions previously inhibitory to their ancestors. Whole-genome sequencing and transcriptomic analysis showed mutations in key genes related to stress response and replication, confirming the importance of these mutations in enhancing the tolerance of S. cerevisiae to harsh environments.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2022)

Article Biotechnology & Applied Microbiology

Metabolic changes of Issatchenkia orientalis under acetic acid stress by transcriptome profile using RNA-sequencing

Yueqi Li et al.

Summary: Under acetic acid stress, the transcriptome of I. orientalis 166 showed significant upregulation of genes involved in ergosterol biosynthesis and energy metabolism, as well as the upregulation of molecular chaperones Hsp70/Hsp90 for protein degradation.

INTERNATIONAL MICROBIOLOGY (2022)

Review Biochemistry & Molecular Biology

Kynurenine Metabolism and Alzheimer's Disease: The Potential Targets and Approaches

Vivek Kumar Sharma et al.

Summary: l-tryptophan, an essential amino acid, plays a role in regulating protein homeostasis and neurotransmitter-mediated physiological events. The metabolism of tryptophan through the kynurenine route leads to the production of metabolites that influence various physiological and pathological outcomes. Imbalances in the kynurenine pathway have been associated with several neurological disorders, including Alzheimer's disease. Pharmacological modulation of this pathway shows promise as a potential therapy for Alzheimer's disease.

NEUROCHEMICAL RESEARCH (2022)

Article Biochemistry & Molecular Biology

Multi-Omics Analysis of Multiple Glucose-Sensing Receptor Systems in Yeast

Shuang Li et al.

Summary: This study investigates the two glucose receptor systems in Saccharomyces cerevisiae and their distinct roles in glucose signaling.

BIOMOLECULES (2022)

Article Environmental Sciences

The exacerbation of soil acidification correlates with structural and functional succession of the soil microbiome upon agricultural intensification

Jie Shen et al.

Summary: Agricultural intensification driven by land-use changes has caused continuous and cumulative soil acidification throughout the global agroecosystem. This study used metagenomic analysis to investigate the microbial community composition and function associated with soil acidification in rice-wheat and rice-vegetable rotations. The results showed that the conversion to rice-vegetable rotations resulted in decreased soil pH and increased acid saturation ratios. The microbial community composition in rice-vegetable rotations was enriched in taxa exhibiting dehydrogenation functions and was more dependent on hydrogen, aluminum, and nitrate nitrogen.

SCIENCE OF THE TOTAL ENVIRONMENT (2022)

Article Biochemistry & Molecular Biology

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

Alba Luengo et al.

Summary: Increasing the activity of the pyruvate dehydrogenase complex impairs cell proliferation by reducing the NAD(+)/NADH ratio, which is caused by increased mitochondrial membrane potential. When demand for NAD(+) exceeds the demand for ATP in cells, aerobic glycolysis is promoted despite available oxygen.

MOLECULAR CELL (2021)

Article Cell Biology

Single-cell resolved imaging reveals intra-tumor heterogeneity in glycolysis, transitions between metabolic states, and their regulatory mechanisms

Hiroshi Kondo et al.

Summary: The study tracks the transition and heritability of metabolic states in single PIK3CA mutant breast cancer cells, identifying non-genetic glycolytic heterogeneity. It reveals distinct subpopulations of cells with regulated glycolytic and mitochondrial metabolism by PI3K signaling, bromodomain activity, and cell crowding effects, showing how targeting these pathways affects specific subpopulations of cancer cells.

CELL REPORTS (2021)

Article Genetics & Heredity

Identification and Functional Analysis of ThADH1 and ThADH4 Genes Involved in Tolerance to Waterlogging Stress in Taxodium hybrid 'Zhongshanshan 406'

Lei Xuan et al.

Summary: The Taxodium hybrid 'Zhongshanshan 406' has been widely used in wetland afforestation in China due to its outstanding flooding tolerance. The study identified and characterized two ADH genes-ThADH1 and ThADH4, which were found to play a key role in the adaptation to anaerobic conditions. Overexpression of these genes in Populus improved waterlogging tolerance, indicating their crucial role in plant survival under low-oxygen conditions.
Review Biotechnology & Applied Microbiology

Classification of acetic acid bacteria and their acid resistant mechanism

Xiaoman Qiu et al.

Summary: Acetic acid bacteria (AAB) play a significant role in vinegar fermentation due to their strong capacity for ethanol oxidation and acetic acid synthesis, but low biomass and production rate caused by acid stress remain major challenges in industrial processes. While acid resistance is crucial for high acidity vinegar production, the mechanisms of acid resistance in AAB are not fully understood yet.

AMB EXPRESS (2021)

Article Microbiology

Overcoming diverse homologous recombinations and single chimeric guide RNA competitive inhibition enhances Cas9-based cyclical multiple genes coediting in filamentous fungi

Youzhi Miao et al.

Summary: This study identified diverse homologous recombination types and competitive inhibition as major obstacles limiting the efficiency of cyclically coediting multiple genes in filamentous fungi. By developing a biased cutting strategy and a new selection marker labelling strategy, a convenient method for cyclically coediting multiple genes in different filamentous fungi was successfully developed. The diverse homologous recombination also provided a useful and convenient one-step approach for gene functional study combining gene disruption and complementation.

ENVIRONMENTAL MICROBIOLOGY (2021)

Article Neurosciences

IDO-1 inhibition protects against neuroinflammation, oxidative stress and mitochondrial dysfunction in 6-OHDA induced murine model of Parkinson's disease

Rupinder Kaur Sodhi et al.

Summary: In this study, 1-Methyltryptophan (1-MT) was tested in a murine model of PD, showing improvements in locomotion, motor coordination, oxidative stress, neuroinflammatory markers, mitochondrial dysfunction, neuronal apoptosis, neurotransmitter levels, and BDNF levels in the striatum. These findings suggest that 1-MT could be a potential candidate for further studies as an alternative in the pharmacotherapy of PD.

NEUROTOXICOLOGY (2021)

Article Biochemistry & Molecular Biology

Acetic acid stress in budding yeast: From molecular mechanisms to applications

Nicoletta Guaragnella et al.

Summary: Acetic acid stress is a common challenge for yeast cells in various environmental conditions and industrial bioprocesses, and its response involves cellular transport, pH homeostasis, metabolism, and stress-signalling pathways.
Article Multidisciplinary Sciences

Oxytocin and vasopressin within the ventral and dorsal lateral septum modulate aggression in female rats

Vinicius Elias de Moura Oliveira et al.

Summary: This study establishes a model of enhanced aggression in virgin female rats and shows that oxytocin and vasopressin systems differentially modulate aggression in distinct neuronal populations of the lateral septum of female rats.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

SRT1720 inhibits the growth of bladder cancer in organoids and murine models through the SIRT1-HIF axis

Ping Tan et al.

Summary: This study demonstrates the potential of cancer organoid-based drug discovery for bladder cancer, identifying SRT1720 as a promising new treatment by targeting Sirt1 and repressing the hypoxia pathway.

ONCOGENE (2021)

Editorial Material Multidisciplinary Sciences

Supplements to treat prediabetes

Chelsea Hepler et al.

SCIENCE (2021)

Article Multidisciplinary Sciences

Intrinsically disordered protein biosensor tracks the physical-chemical effects of osmotic stress on cells

Cesar L. Cuevas-Velazquez et al.

Summary: This study introduces a new FRET biosensor, SED1, developed using Arabidopsis intrinsically disordered AtLEA4-5 protein to monitor osmotic stress induced changes in cells. The biosensor demonstrates high sensitivity to osmolarity changes and shows near-linear responses in various living cells, offering a valuable tool for studying water-associated stress. The research highlights the potential of intrinsically disordered protein regions as environmentally-responsive molecular tools across different organisms.

NATURE COMMUNICATIONS (2021)

Article Biotechnology & Applied Microbiology

Different Gene Expression Patterns of Hexose Transporter Genes Modulate Fermentation Performance of Four Saccharomyces cerevisiae Strains

Chiara Nadai et al.

Summary: The study investigated the gene expression of hexose transporters in Saccharomyces cerevisiae during late fermentation phase and found that different strains exhibit specific gene expression profiles, redefining the importance of certain transporter genes previously thought to be key players in sugar transport. This suggests that the overall expression level of transporter genes plays a crucial role in modulating the late fermentation process and total sugar consumption.

FERMENTATION-BASEL (2021)

Article Medicine, General & Internal

Mulberry leaves extract ameliorates alcohol-induced liver damages through reduction of acetaldehyde toxicity and inhibition of apoptosis caused by oxidative stress signals

Hsin-Wen Liang et al.

Summary: Mulberry leaf extract showed significant hepatoprotective effects against acute alcohol-induced liver damages by reducing acetaldehyde toxicity and inhibiting liver cell apoptosis. The findings suggest that mulberry leaf extract may be a potential agent for treating alcohol liver disease.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2021)

Review Biotechnology & Applied Microbiology

Microbial response to acid stress: mechanisms and applications

Ningzi Guan et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2020)

Article Biodiversity Conservation

Dramatic loss of inorganic carbon by nitrogen-induced soil acidification in Chinese croplands

Sajjad Raza et al.

GLOBAL CHANGE BIOLOGY (2020)

Article Environmental Sciences

Soil acidification in Chinese tea plantations

Peng Yan et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2020)

Article Biotechnology & Applied Microbiology

The alcohol dehydrogenase gene family in sugarcane and its involvement in cold stress regulation

Weihua Su et al.

BMC GENOMICS (2020)

Article Multidisciplinary Sciences

Channelrhodopsin-mediated optogenetics highlights a central role of depolarization-dependent plant proton pumps

Antonella Reyer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Real-time monitoring of the in vivo redox state transition using the ratiometric redox state sensor protein FROG/B

Kazunori Sugiura et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Biochemistry & Molecular Biology

Oxidative Stress Orchestrates MAPK and Nitric-Oxide Synthase Signal

Tsuyoshi Takata et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Biotechnology & Applied Microbiology

Saccharomyces cerevisiae Cytosolic Thioredoxins Control Glycolysis, Lipid Metabolism, and Protein Biosynthesis under Wine-Making Conditions

Cecilia Picazo et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2019)

Article Biotechnology & Applied Microbiology

Overexpression of RCK1 improves acetic acid tolerance in Saccharomyces cerevisiae

Eun Joong Oh et al.

JOURNAL OF BIOTECHNOLOGY (2019)

Review Plant Sciences

Consequences of Oxidative Stress on Plant Glycolytic and Respiratory Metabolism

Sebastien Dumont et al.

FRONTIERS IN PLANT SCIENCE (2019)

Article Multidisciplinary Sciences

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors

Rani K. Powers et al.

NATURE COMMUNICATIONS (2019)

Article Biotechnology & Applied Microbiology

Reverse metabolic engineering in lager yeast: impact of the NADH/NAD+ ratio on acetaldehyde production during the brewing process

Xin Xu et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)

Article Biotechnology & Applied Microbiology

The emerging role of aldehyde:ferredoxin oxidoreductases in microbially-catalyzed alcohol production

Laura Sofie Nissen et al.

JOURNAL OF BIOTECHNOLOGY (2019)

Article Agriculture, Multidisciplinary

Effects of long-term nitrogen application on soil acidification and solution chemistry of a tea plantation in China

Xiang-de Yang et al.

AGRICULTURE ECOSYSTEMS & ENVIRONMENT (2018)

Article Biochemistry & Molecular Biology

NAD+/NADH homeostasis affects metabolic adaptation to hypoxia and secondary metabolite production in filamentous fungi

Motoyuki Shimizu

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2018)

Article Cell Biology

ENO2 Promotes Cell Proliferation, Glycolysis, and Glucocorticoid-Resistance in Acute Lymphoblastic Leukemia

Cheng-cheng Liu et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)

Article Multidisciplinary Sciences

Single cell analysis of kynurenine and System L amino acid transport in T cells

Linda V. Sinclair et al.

NATURE COMMUNICATIONS (2018)

Article Genetics & Heredity

Genetic Analysis of Signal Generation by the Rgt2 Glucose Sensor of Saccharomyces cerevisiae

Peter Scharff-Poulsen et al.

G3-GENES GENOMES GENETICS (2018)

Article Pharmacology & Pharmacy

Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota

Xiao-Jun Zhang et al.

PHARMACOLOGICAL RESEARCH (2018)

Review Biochemistry & Molecular Biology

Redox imbalance stress in diabetes mellitus: Role of the polyol pathway

Liang-jun Yan

ANIMAL MODELS AND EXPERIMENTAL MEDICINE (2018)

Article Cell Biology

pHuji, a pH-sensitive red fluorescent protein for imaging of exo- and endocytosis

Yi Shen et al.

JOURNAL OF CELL BIOLOGY (2014)

Review Biochemistry & Molecular Biology

Decarboxylation of Pyruvate to Acetaldehyde for Ethanol Production by Hyperthermophiles

Mohammad S. Eram et al.

BIOMOLECULES (2013)

Review Endocrinology & Metabolism

The dynamic regulation of NAD metabolism in mitochondria

Liana Roberts Stein et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)

Article Biochemistry & Molecular Biology

Achievements and perspectives in yeast acetic acid-induced programmed cell death pathways

Nicoletta Guaragnella et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2011)

Article Biochemical Research Methods

Optical sensors for monitoring dynamic changes of intracellular metabolite levels in mammalian cells

Bi-Huei Hou et al.

NATURE PROTOCOLS (2011)

Article Chemistry, Inorganic & Nuclear

Synthesis, spectroscopy and crystal structure determination of heteroleptic cobalt(II) silanethiolates with pyridine derivatives

Agnieszka Pladzyk et al.

TRANSITION METAL CHEMISTRY (2010)

Review Plant Sciences

Regulation and function of root exudates

Dayakar V. Badri et al.

PLANT CELL AND ENVIRONMENT (2009)

Review Biochemistry & Molecular Biology

Fungal respiration: a fusion of standard and alternative components

T Joseph-Horne et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2001)