相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts
Daniel DiCorpo et al.
DIABETES CARE (2022)
Heterogeneity in phenotype, disease progression and drug response in type 2 diabetes
Anand Thakarakkattil Narayanan Nair et al.
NATURE MEDICINE (2022)
Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes
Robert Wagner et al.
NATURE MEDICINE (2021)
Single-cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk
Joshua Chiou et al.
NATURE GENETICS (2021)
The impact of non-additive genetic associations on age-related complex diseases
Marta Guindo-Martinez et al.
NATURE COMMUNICATIONS (2021)
Repositioning Glucagon Action in the Physiology and Pharmacology of Diabetes
Brian Finan et al.
DIABETES (2020)
Classification of Type 2 Diabetes Genetic Variants and a Novel Genetic Risk Score Association With Insulin Clearance
Mark O. Goodarzi et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2020)
Serum lipoprotein (a) associates with a higher risk of reduced renal function: a prospective investigation
Liping Xuan et al.
JOURNAL OF LIPID RESEARCH (2020)
The clinical consequences of heterogeneity within and between different diabetes types
Maria J. Redondo et al.
DIABETOLOGIA (2020)
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Jason Flannick et al.
NATURE (2019)
Exome sequencing of Finnish isolates enhances rare-variant association power
Adam E. Locke et al.
NATURE (2019)
A catalog of genetic loci associated with kidney function from analyses of a million individuals
Matthias Wuttke et al.
NATURE GENETICS (2019)
Genome-Wide Association Study on the Early-Phase Insulin Response to a Liquid Mixed Meal: Results From the NEO Study
Ruifang Li-Gao et al.
DIABETES (2019)
Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen
Rany M. Salem et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2019)
A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes
Natalie R. van Zuydam et al.
DIABETES (2018)
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Anubha Mahajan et al.
NATURE GENETICS (2018)
Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Silvia Bonas-Guarch et al.
NATURE COMMUNICATIONS (2018)
Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables
Emma Ahlqvist et al.
LANCET DIABETES & ENDOCRINOLOGY (2018)
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease
Pim van der Harst et al.
CIRCULATION RESEARCH (2018)
Increased β-Cell Workload Modulates Proinsulin-to-Insulin Ratio in Humans
Teresa Mezza et al.
DIABETES (2018)
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis
Miriam S. Udler et al.
PLOS MEDICINE (2018)
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
Anubha Mahajan et al.
NATURE GENETICS (2018)
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance
Luca A. Lotta et al.
NATURE GENETICS (2017)
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes
Arushi Varshney et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Kringle IV Type 2, Not Low Lipoprotein(a), as a Cause of Diabetes: A Novel Genetic Approach Using SNPs Associated Selectively with Lipoprotein(a) Concentrations or with Kringle IV Type 2 Repeats
Andra Tolbus et al.
CLINICAL CHEMISTRY (2017)
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
Robert A. Scott et al.
DIABETES (2017)
Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice
Gaelle R. Carrat et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2017)
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease
Nathan O. Stitziel et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
ABO blood group system and the coronary artery disease: an updated systematic review and meta-analysis
Zhuo Chen et al.
SCIENTIFIC REPORTS (2016)
An eMERGE Clinical Center at Partners Personalized Medicine
Jordan W. Smoller et al.
JOURNAL OF PERSONALIZED MEDICINE (2016)
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease
Majid Nikpay et al.
NATURE GENETICS (2015)
Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits
Joseph K. Pickrell
AMERICAN JOURNAL OF HUMAN GENETICS (2014)
Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity
Antigone S. Dimas et al.
DIABETES (2014)
Genetic Evidence for a Normal-Weight Metabolically Obese Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes
Hanieh Yaghootkar et al.
DIABETES (2014)
Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes
Anders H. Rosengren et al.
DIABETES (2012)
ChromHMM: automating chromatin-state discovery and characterization
Jason Ernst et al.
NATURE METHODS (2012)
Genetics of Obesity: What have we Learned?
Helene Choquet et al.
CURRENT GENOMICS (2011)
Lipoprotein(a) and Risk of Type 2 Diabetes
Samia Mora et al.
CLINICAL CHEMISTRY (2010)
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes
John R. B. Perry et al.
HUMAN MOLECULAR GENETICS (2010)
Lipoprotein(a) Concentration and the Risk of Coronary Heart Disease, Stroke, and Nonvascular Mortality
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
A Bayesian measure of the probability of false discovery in genetic epidemiology studies
Jon Wakefield
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
分享论文
