Comparison of faster-acting aspart with insulin aspart under conditions mimicking underestimation or missed meal boluses in type 1 diabetes using closed-loop insulin delivery

Article Endocrinology & Metabolism

Fast-Acting Insulin Aspart Use with the MiniMedTM 670G System

Liana Hsu et al.

Summary: The study assessed the efficacy and safety of ultrarapid insulin Fiasp in the hybrid closed-loop MiniMed 670G system. Results showed that both Novolog and Fiasp produced clinically similar glycemic outcomes in the system's auto mode, with a slight increase in daily insulin requirements using Fiasp.

DIABETES TECHNOLOGY & THERAPEUTICS (2021)

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Article Endocrinology & Metabolism

Fast Acting Insulin Aspart Compared with Insulin Aspart in the Medtronic 670G Hybrid Closed Loop System in Type 1 Diabetes: An Open Label Crossover Study

Kerem Ozer et al.

Summary: This study compared the efficacy and safety of fast acting insulin aspart (FA) with insulin aspart (IAsp) in patients with type 1 diabetes using the Medtronic 670G system in auto mode. Results showed that treatment with FA in a hybrid closed loop system led to better blood glucose control, with patients spending more time in the target range and experiencing lower postprandial glucose increases.

DIABETES TECHNOLOGY & THERAPEUTICS (2021)

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Article Endocrinology & Metabolism

Hybrid closed-loop glucose control with faster insulin aspart compared with standard insulin aspart in adults with type 1 diabetes: A double-blind, multicentre, multinational, randomized, crossover study

Charlotte K. Boughton et al.

Summary: The study found that the use of Fiasp in the CamAPS FX closed-loop system may reduce hypoglycemia without compromising glucose control in adults with T1D.

DIABETES OBESITY & METABOLISM (2021)

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Review Endocrinology & Metabolism

Automated insulin dosing systems: Advances after a century of insulin

Hood Thabit et al.

Summary: The complexities of insulin therapy and glucose variability in type 1 diabetes continue to pose challenges. Automated insulin dosing (AID) systems have shown efficacy, safety, and positive effects on quality of life. Ongoing research is exploring ways to further improve closed-loop insulin delivery systems.

DIABETIC MEDICINE (2021)

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Article Endocrinology & Metabolism