期刊
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
卷 65, 期 5, 页码 611-624出版社
WILEY
DOI: 10.1111/dmcn.15513
关键词
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Single-case experimental designs (SCEDs) are a set of methodologies used to test the effectiveness of interventions at the individual level using rigorous and prospective methods. SCEDs offer flexibility in research design and can inform clinical decision-making, particularly for personalized outcomes, families with complex needs, and measuring progress based on parental intervention implementation and personal goals.
Single-case experimental designs (SCEDs) are a group of methodologies of growing interest, aiming to test the effectiveness of an intervention at the single-participant level, using a rigorous and prospective methodology. SCEDs may promote flexibility on how we design research protocols and inform clinical decision-making, especially for personalized outcome measures, inclusion of families with challenging needs, measurement of children's progress in relation to parental implementation of interventions, and focus on personal goals. Design options for SCEDs are discussed in relation to an expected on/off effect of the intervention (e.g. school/environmental adaptation, assistive technology devices) or, alternatively, on an expected carry-on/maintenance of effects (interventions aiming to develop or restore a function). Randomization in multiple-baseline designs and 'power' calculations are explained. The most frequent reasons for not detecting an intervention effect in SCEDs are also presented, especially in relation to baseline length, trend, and instability. The use of SCEDs on the front and back ends of randomized controlled trials is discussed.
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