4.7 Article

?Np63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Oncology

Linking EMT programmes to normal and neoplastic epithelial stem cells

Arthur W. Lambert et al.

Summary: Epithelial stem cells play critical roles in tissue generation, maintenance, and repair, while cancer stem cells are implicated in the growth and recurrence of many carcinomas. The activation of epithelial-mesenchymal transition (EMT) is linked to the formation of both normal and neoplastic stem cells, but the mechanistic basis of this connection remains unclear. Understanding the elusive links between EMT programs and the stem cell state will advance our knowledge of normal stem cell biology and cancer pathogenesis.

NATURE REVIEWS CANCER (2021)

Article Biochemistry & Molecular Biology

Regulation of Collective Metastasis by Nanolumenal Signaling

Emma D. Wrenn et al.

Article Multidisciplinary Sciences

Alveolar regeneration through a Krt8+transitional stem cell state that persists in human lung fibrosis

Maximilian Strunz et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells

Cornelia Kroger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biochemistry & Molecular Biology

Control of p53-dependent transcription and enhancer activity by the p53 family member p63

Gizem Karsli Uzunbas et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Review Immunology

Context-dependent EMT programs in cancer metastasis

Nicole M. Aiello et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2019)

Article Multidisciplinary Sciences

Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell

Arshad Ayyaz et al.

NATURE (2019)

Article Multidisciplinary Sciences

Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ

Lina Ding et al.

NATURE COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding

Sofia Gkountela et al.

Review Cell & Tissue Engineering

Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance

Piyush B. Gupta et al.

CELL STEM CELL (2019)

Review Cell Biology

EMT Transition States during Tumor Progression and Metastasis

Ievgenia Pastushenko et al.

TRENDS IN CELL BIOLOGY (2019)

Review Oncology

Controversies around epithelial-mesenchymal plasticity in cancer metastasis

Elizabeth D. Williams et al.

NATURE REVIEWS CANCER (2019)

Article Cell Biology

Integrin-beta 4 is a novel transcriptional target of TAp73

Ningxia Xie et al.

CELL CYCLE (2018)

Article Multidisciplinary Sciences

Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche

Rumela Chakrabarti et al.

SCIENCE (2018)

Article Multidisciplinary Sciences

Identification of the tumour transition states occurring during EMT

Ievgenia Pastushenko et al.

NATURE (2018)

Article Medicine, Research & Experimental

ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer

Sushil Kumar et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Review Oncology

Stem cell fate in cancer growth, progression and therapy resistance

Nikki K. Lytle et al.

NATURE REVIEWS CANCER (2018)

Review Biochemistry & Molecular Biology

Cancer stem cells revisited

Eduard Batlle et al.

NATURE MEDICINE (2017)

Review Oncology

EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

Tsukasa Shibue et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2017)

Article Multidisciplinary Sciences

Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells

Brian Bierie et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Defining stem cell dynamics and migration during wound healing in mouse skin epidermis

Mariaceleste Aragona et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Stem Cell Lineage Infidelity Drives Wound Repair and Cancer

Yejing Ge et al.

Review Biochemistry & Molecular Biology

Emerging Biological Principles of Metastasis

Arthur W. Lambert et al.

Article Biochemistry & Molecular Biology

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

Anthony Mathelier et al.

NUCLEIC ACIDS RESEARCH (2016)

Review Biochemistry & Molecular Biology

EMT: 2016

M. Angela Nieto et al.

Review Cell Biology

Distinctive properties of metastasis-initiating cells

Toni Celia-Terrassa et al.

GENES & DEVELOPMENT (2016)

Review Cell & Tissue Engineering

Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast Cancer

Michael D. Brooks et al.

CELL STEM CELL (2015)

Article Multidisciplinary Sciences

Integrative analysis of 111 reference human epigenomes

Anshul Kundaje et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E. Ritchie et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Multidisciplinary Sciences

p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling

Elisa Maria Memmi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Review Biochemistry & Molecular Biology

Maintaining epithelial stemness with p63

Gerry Melino et al.

SCIENCE SIGNALING (2015)

Review Biochemistry & Molecular Biology

Maintaining epithelial stemness with p63

Gerry Melino et al.

SCIENCE SIGNALING (2015)

Review Oncology

Implications of the hybrid epithelial/mesenchymal phenotype in metastasis

Mohit Kumar Jolly et al.

FRONTIERS IN ONCOLOGY (2015)

Article Multidisciplinary Sciences

Identification of multipotent mammary stemcells by protein C receptor expression

Daisong Wang et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

Nicola Aceto et al.

Review Cell & Tissue Engineering

Metastatic Stem Cells: Sources, Niches, and Vital Pathways

Thordur Oskarsson et al.

CELL STEM CELL (2014)

Letter Biochemical Research Methods

Improved vectors and genome-wide libraries for CRISPR screening

Neville E. Sanjana et al.

NATURE METHODS (2014)

Article Biotechnology & Applied Microbiology

Tackling the cancer stem cells - what challenges do they pose?

Diwakar R. Pattabiraman et al.

NATURE REVIEWS DRUG DISCOVERY (2014)

Article Biochemistry & Molecular Biology

Systematic discovery and characterization of regulatory motifs in ENCODE TF binding experiments

Pouya Kheradpour et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Cell Biology

Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome

David A. Orlando et al.

CELL REPORTS (2014)

Article Medicine, Research & Experimental

p53/p63/p73 in the Epidermis in Health and Disease

Vladimir A. Botchkarev et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2014)

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

Article Biochemical Research Methods

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin et al.

BIOINFORMATICS (2013)

Article Biochemistry & Molecular Biology

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte et al.

Article Biochemistry & Molecular Biology

Super-Enhancers in the Control of Cell Identity and Disease

Denes Hnisz et al.

Article Biochemistry & Molecular Biology

DNA-Binding Specificities of Human Transcription Factors

Arttu Jolma et al.

Review Multidisciplinary Sciences

Tumour heterogeneity and cancer cell plasticity

Corbin E. Meacham et al.

NATURE (2013)

Article Cell Biology

The perivascular niche regulates breast tumour dormancy

Cyrus M. Ghajar et al.

NATURE CELL BIOLOGY (2013)

Review Oncology

Unravelling cancer stem cell potential

Benjamin Beck et al.

NATURE REVIEWS CANCER (2013)

Article Biochemistry & Molecular Biology

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

Wenjun Guo et al.

Article Medicine, Research & Experimental

Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells

Toni Celia-Terrassa et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Article Multidisciplinary Sciences

Distinct contribution of stem and progenitor cells to epidermal maintenance

Guilhem Mascre et al.

NATURE (2012)

Article Biochemical Research Methods

FIMO: scanning for occurrences of a given motif

Charles E. Grant et al.

BIOINFORMATICS (2011)

Article Multidisciplinary Sciences

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

Christine L. Chaffer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Cell Biology

p63 and p73, the Ancestors of p53

V. Doetsch et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Cancer stem cells: mirage or reality?

Piyush B. Gupta et al.

NATURE MEDICINE (2009)

Article Biochemistry & Molecular Biology

UniPROBE: an online database of protein binding microarray data on protein-DNA interactions

Daniel E. Newburger et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Biochemistry & Molecular Biology

The epithelial-mesenchymal transition generates cells with properties of stem cells

Sendurai A. Mani et al.

Article Multidisciplinary Sciences

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition

Anne-Pierre Morel et al.

PLOS ONE (2008)

Article Biotechnology & Applied Microbiology

Model-based Analysis of ChIP-Seq (MACS)

Yong Zhang et al.

GENOME BIOLOGY (2008)

Article Genetics & Heredity

A module of negative feedback regulators defines growth factor signaling

Ido Amit et al.

NATURE GENETICS (2007)

Article Oncology

Thirteen new p53 gene mutants identified among 41 human breast cancer cell lines

Marijke Wasielewski et al.

BREAST CANCER RESEARCH AND TREATMENT (2006)

Article Cell Biology

p63 regulates an adhesion programme and cell survival in epithelial cells

Danielle K. Carroll et al.

NATURE CELL BIOLOGY (2006)

Article Multidisciplinary Sciences

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

A Subramanian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemical Research Methods

Open source clustering software

MJL de Hoon et al.

BIOINFORMATICS (2004)

Article Biochemistry & Molecular Biology

Lentivirus-delivered stable gene silencing by RNAi in primary cells

SA Stewart et al.

Article Multidisciplinary Sciences

Prospective identification of tumorigenic breast cancer cells

M Al-Hajj et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)