Multifaceted role of silver salts as ligand scavengers and different behavior of nickel and palladium complexes: beyond halide abstraction

The reaction of [NiArBr(PPh3)(2)] with AgBF4 brings about the abstraction of both the halide and phosphine from the nickel center by silver. When the reaction is carried out in CH2Cl2/toluene a mixture of the cationic aquo derivatives [NiAr(H2O)(PPh3)(2)]BF4 (2) and [NiAr(H2O)(2)(PPh3)]BF4 (3) is formed, along with AgBr and [Ag(PPh3)(n)]BF4. When the same reaction is carried out in acetone as the solvent, it leads to the completely different complex [NiAr(kappa(2)-O, O-MeC(O)CH2C(OH)Me-2)(PPh3)] (5), bearing a chelating ligand formed by the aldol self-condensation of acetone. Phosphine abstraction by silver is less favorable for the analogous palladium(ii) complexes and only occurs if a large excess of AgBF4 is used. Thus, silver salts can be safely used as halide scavengers for palladium derivatives. However, the generation of cationic Ni complexes from neutral precursors by halide extraction with a silver salt may produce naked species, different than those expected, and highly reactive in certain media.

Automated summary

The reaction between [NiArBr(PPh3)(2)] and AgBF4 results in the abstraction of halide and phosphine from the nickel center by silver. The reaction in CH2Cl2/toluene solvent forms cationic aquo derivatives [NiAr(H2O)(PPh3)(2)]BF4 and [NiAr(H2O)(2)(PPh3)]BF4, while in acetone solvent, it forms a complex [NiAr(kappa(2)-O, O-MeC(O)CH2C(OH)Me-2)(PPh3)] with a chelating ligand formed by the aldol self-condensation of acetone. Phosphine abstraction by silver is less favorable for palladium(ii) complexes and only occurs under certain conditions.