期刊
CURRENT OPINION IN PEDIATRICS
卷 35, 期 2, 页码 239-244出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOP.0000000000001210
关键词
crystalloid intravenous fluid; fluid overload; isotonic fluids; paediatric
类别
This review summarizes current literature on fluid management for critically ill children, including crystalloid fluid used throughout the critical illness course, management of fluid output, and complications with fluid overload. Recent studies show mixed results regarding the risk of mortality and kidney injury with 0.9% saline and crystalloid fluid. Fluid restrictive strategies may be well tolerated in critically ill adults with septic shock, but further trials are needed in pediatrics. High-quality studies are needed to define the type, timing, and rate of intravenous fluid for critically ill children.
Purpose of reviewThis review summarizes current literature pertaining to fluid management for critically ill children. It includes an overview on crystalloid fluid used throughout the critical illness course, management of fluid output and complications with fluid overload.Recent findingsObservational paediatric studies and adult randomized trials show mixed results regarding risk of mortality and kidney injury with 0.9% saline and crystalloid fluid. A recent adult randomized trial suggests that a fluid restrictive strategy may be well tolerated in critically ill adults with septic shock, but further randomized trials are needed in paediatrics. Fluid overload has been associated with increased morbidity and mortality. Trials exploring ways to decrease fluid accumulation must be done in paediatrics.Additional high-quality studies are needed to precisely define the type, timing and rate of intravenous fluid critically ill children should receive throughout their clinical illness course.
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