Nanoliposomal delivery systems of natural antibacterial compounds; properties, applications, and recent advances

Todays, nanoliposomes (NLPs) are considered as one of the most efficient nanocarriers to deal with bacteria, practically in food products. These nanodelivery systems are able to be loaded with different bioactive compounds. The main aim of this review is investigating recent approaches (mostly from the years of 2018 to 2022) regarding development of nanoliposomal natural antibacterial compounds. In this regard, NLPs alone, combined with films, coatings, or fibers, and in coated forms are reviewed as advanced delivery systems of antibacterial substances. Moreover, a robust and comprehensive coverage of the morphological and physical properties of formulated NLPs as well as their interactions with antibacterial substances are discussed. The importance of NLPs to encapsulate antibacterial ingredients, advantages and drawbacks, antibacterial pathways of formulated NLPs, and comparison of them with pure antibacterial bioactive compounds are also explained.

Automated summary

This review investigates recent approaches towards the development of nanoliposomal natural antibacterial compounds. It discusses the morphological and physical properties of formulated NLPs and their interactions with antibacterial substances. The importance of NLPs in encapsulating antibacterial ingredients and their comparison with pure antibacterial bioactive compounds are also explained.