期刊
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING
卷 404, 期 -, 页码 -出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.cma.2022.115812
关键词
Constitutive modeling; Nonlinear elasticity; Tissue biomechanics; Gaussian processes; Stochastic finite element analysis; Machine learning
Data-based approaches are a promising alternative to traditional analytical constitutive models for solid mechanics. This study proposes a Gaussian process-based constitutive modeling framework for planar, hyperelastic, and incompressible soft tissues. The strain energy density of soft tissues is modeled as a Gaussian process and can be regressed to experimental stress-strain data. The proposed framework can be trained with limited experimental data and provides a straightforward way of quantifying uncertainty in simulation-based predictions.
Data-based approaches are promising alternatives to the traditional analytical constitutive models for solid mechanics. Herein, we propose a Gaussian process (GP) based constitutive modeling framework, focusing on planar, hyperelastic and incompressible soft tissues. Specifically, the strain energy density of soft tissues is modeled as a GP, which can be regressed to experimental stress-strain data obtained from biaxial stretching experiments. Moreover, the GP model can be weakly constrained to be convex. A key advantage of a GP-based model is that, in addition to the mean value, it provides a probability density (i.e. associated uncertainty) for the strain energy density. To simulate the effect of this uncertainty, a non-intrusive stochastic finite element analysis (SFEA) framework is proposed. The proposed framework is verified against an artificial dataset based on the Gasser-Ogden-Holzapfel model and applied to a real experimental dataset of a porcine aortic valve leaflet tissue. The results show that the proposed framework can be trained with limited experimental data and fits the data better than several existing models. The SFEA framework provides a straightforward way of using the experimental data and quantifying the resulting uncertainty in simulation-based predictions.(c) 2022 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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