4.7 Article

Enzyme mimic nanomaterials as nanozymes with catalytic attributes

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DOI: 10.1016/j.colsurfb.2022.112950

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Nanozymes; Catalytic nanomaterials; Nanobiology; Efficient nanomaterials

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Nanozymes are efficient nanomaterials with enzyme-like characteristics, which have attracted researchers' attention as alternatives to natural enzymes. Despite their unique physicochemical properties and catalytic activity, constraints such as denaturation, high manufacturing cost, and reutilization challenges have hindered their deployment in industrial processes. The article provides an overview of nanozyme research, compares them with natural and synthetic enzymes, and highlights their distinct properties and applications in various fields, introducing a new field called nanozymology.
Nanozymes are super-efficient nanomaterials with enzyme-like characteristics, as the name suggests. In the last decade, efforts have been made to develop artificial enzymes, which are alternatives to natural enzymes. As nanoscience and nanotechnology advance, nanozymes, which are catalytic nanomaterials having enzyme-like properties, have fascinated researchers' attention. Nanozymes with unique physicochemical properties and nanomaterials that mimic catalytic activity have gained a special interest in the industrial sectors. However, several constraints have hampered their effective deployment in industrial processes, including denaturation, time-consuming manufacturing, overall high cost-ratio, and reutilization challenges. After a brief overview of nanozyme research, an analysis of the similarities and differences between nanozymes and natural and synthetic enzymes is presented. Because of their distinct properties, nanozymes stand out in this comparison. Nanozymes have exhibited a variety of applications leveraging the physiochemical properties of nanomaterials, ranging from in vitro detection to enzyme substitution in biological systems. In addition, nanozymes have introduced a new field called nanozymology, which blends nanotechnology with enzymology.

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