18F-FDG PET/CT Imaging of G-CSF-Producing Inflammatory Myofibroblastic Tumor of the Pleura

We report a case of granulocyte colony-stimulating factor (G-CSF)-producing inflammatory myofibroblastic tumor of the pleura in a 71-year-old man. Contrast-enhanced CT demonstrated multiple pleural masses with pulmonary hilar lymph nodes swelling. F-18-FDG PET/CT demonstrated marked focal FDG uptake in the thoracic masses with diffuse uptake in the bone marrow. Based on the pathological findings and elevated serum G-CSF level, the patient was diagnosed as G-CSF-producing inflammatory myofibroblastic tumor. Because G-CSF-producing tumors demonstrate aggressive clinical course, early and accurate diagnosis is important.

Automated summary

We present a case of G-CSF-producing inflammatory myofibroblastic tumor in a 71-year-old man with multiple pleural masses and pulmonary hilar lymph nodes swelling. Imaging studies showed focal FDG uptake in the thoracic masses and diffuse uptake in the bone marrow. Based on pathology and elevated serum G-CSF level, the patient was diagnosed with G-CSF-producing inflammatory myofibroblastic tumor. Early and accurate diagnosis is crucial due to the aggressive clinical course of G-CSF-producing tumors.