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Development of desquamation with Staphylococcus aureus colonization in patients with atopic dermatitis under treatment with upadacitinib

CLINICAL AND EXPERIMENTAL DERMATOLOGY (2023)

Development of tinea corporis in a Japanese patient with atopic dermatitis under treatment with upadacitinib in a real-world clinical setting: Possible contribution of the suppression of Th17

Akihiko Uchiyama et al.

Summary: We report a rare case of a patient with AD who developed tinea corporis during upadacitinib treatment in a real-world clinical setting. Our hypothesis is that the suppressive effect of Th17 immunity by upadacitinib possibly contributed to the development of tinea corporis.

JOURNAL OF CUTANEOUS IMMUNOLOGY AND ALLERGY (2022)

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Article Medicine, General & Internal

Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double- blind, randomised controlled phase 3 trials

Emma Guttman-Yassky et al.

Summary: The clinical trials demonstrated that Upadacitinib may be an effective treatment option for moderate-to-severe atopic dermatitis, with a significant improvement in symptoms for most patients within 16 weeks, and both dosages were well tolerated.

LANCET (2021)

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Article Dermatology

Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis A Randomized Clinical Trial

Andrew Blauvelt et al.

Summary: This study compared the safety and efficacy of upadacitinib vs dupilumab in patients with moderate-to-severe atopic dermatitis, with the results showing superior efficacy of upadacitinib at week 16 compared to dupilumab, with no new safety signals identified.

JAMA DERMATOLOGY (2021)

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Article Dermatology

IL-4R alpha Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis

Chris Callewaert et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2020)

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Review Dermatology

The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group

H. Alexander et al.

BRITISH JOURNAL OF DERMATOLOGY (2020)

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Development of desquamation with Staphylococcus aureus colonization in patients with atopic dermatitis under treatment with upadacitinib

相关参考文献

Development of tinea corporis in a Japanese patient with atopic dermatitis under treatment with upadacitinib in a real-world clinical setting: Possible contribution of the suppression of Th17

Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double- blind, randomised controlled phase 3 trials

Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis A Randomized Clinical Trial

IL-4R alpha Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis

The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group

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