4.6 Article

Quinoid Conjugated Polymer Nanoparticles with NIR-II Absorption Peak Toward Efficient Photothermal Therapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Supramolecular Vesicles Based on Gold Nanorods for Precise Control of Gene Therapy and Deferred Photothermal Therapy

Ludan Yue et al.

Summary: In this study, a facile strategy was proposed to remotely control intracellular gene expression using gold nanorods (Au NRs) as gene carriers and photothermal transducers. This strategy allows precise spatiotemporal initiation of gene expression and deferred photothermal therapy, leading to enhanced therapeutic outcomes.

CCS CHEMISTRY (2022)

Article Chemistry, Multidisciplinary

High-Performance All-Small-Molecule Organic Solar Cells Enabled by Regio-Isomerization of Noncovalently Conformational Locks

Xin Zhang et al.

Summary: By using noncovalent conformational locks (NoCLs), a pair of regioisomeric small-molecule donors (SMDs) has been synthesized, and the significant influence of regioisomeric effect on device performance has been demonstrated. Among different SMDs, BT-O2 exhibits better performance, and the introduction of fullerene derivative PC71BM further improves the performance.

ADVANCED FUNCTIONAL MATERIALS (2022)

Review Chemistry, Multidisciplinary

Modulating the optical properties and functions of organic molecules through polymerization

Wenbo Wu et al.

Summary: Organic functional materials have broad applications in various fields, and their optical properties can be improved through simple polymerization. Polymerization can enhance properties such as spectral shift, photosensitization, two-photon absorption, photocatalytic efficiency, phosphorescence, delayed fluorescence, and emission. The opportunities for designing high performance optical materials using polymerization are promising.

MATERIALS HORIZONS (2022)

Article Chemistry, Multidisciplinary

Unravelling the Role of Electron Acceptors for the Universal Enhancement of Charge Transport in Quinoid-Donor-Acceptor Polymers for High-Performance Transistors

Huanhuan Liang et al.

Summary: The quinoid-donor-acceptor (Q-D-A) strategy shows promise in constructing high mobility semiconducting polymers. This study synthesized and characterized new polymers with different electron acceptor units and backbone coplanarity to explore the potential of this strategy. Q-D-A polymers exhibited more planar backbone conformations than their donor-acceptor (D-A) counterparts. Organic field-effect transistors based on Q-D-A polymers demonstrated excellent effective hole mobilities, which were significantly higher than those of D-A polymers. The role of electron acceptors in Q-D-A polymers was comprehensively investigated, revealing increased film crystallinity, smaller effective hole masses, and improved operational stability for polymers with stronger acceptor units. This study provides valuable insights into the structure-property-device performance relationship for high performance semiconducting polymers using the Q-D-A strategy.

ADVANCED FUNCTIONAL MATERIALS (2022)

Review Engineering, Biomedical

Recent Progress in the Development of Multifunctional Nanoplatform for Precise Tumor Phototherapy

Junjie Liu et al.

Summary: The key to precise tumor phototherapy is to ensure that ROS or heat is specifically generated at the tumor site, while the phototoxicity of conventional PAs is one of the main challenges for their potential clinical application. Through targeted delivery of PAs and activatable phototherapy strategies based on nanocarriers, precise treatment of tumors can be achieved.

ADVANCED HEALTHCARE MATERIALS (2021)

Review Nanoscience & Nanotechnology

Functional nanoparticles through π-conjugated polymer self-assembly

Liam R. MacFarlane et al.

Summary: pi-Conjugated polymers exhibit diverse electronic and optical properties. This review discusses the preparation of self-assembled nanoparticles from these polymers and their applications in optoelectronics, biomedical imaging and therapy, photocatalysis, and sensing. The development of pi-conjugated polymers has opened up new possibilities for functional organic materials similar to inorganic semiconductors, with nanoparticles based on these polymers showing promise in various emerging applications.

NATURE REVIEWS MATERIALS (2021)

Article Chemistry, Multidisciplinary

Donor/π-Bridge Manipulation for Constructing a Stable NIR-II Aggregation-Induced Emission Luminogen with Balanced Phototheranostic Performance**

Dingyuan Yan et al.

Summary: The study successfully constructed highly stable NIR-II AIEgen DPBTA-DPTQ nanoparticles using benzo[c]thiophene as an electron-rich and bulky donor/π-bridge, achieving acceptable fluorescence quantum yield and excellent photothermal conversion efficiency. DPBTA-DPTQ showed good biocompatibility and efficient photothermal therapeutic effects in in vitro tests, demonstrating potential for photothermal eradication of tumors in mouse models.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Organic Nanoparticles with Persistent Luminescence for In Vivo Afterglow Imaging-Guided Photodynamic Therapy

Xiaokun Zheng et al.

Summary: This study utilized organic nanoparticles (ONPs) for afterglow imaging-guided photodynamic therapy (PDT), achieving high SBR and good tissue penetration for effective tumor growth suppression in mice with minimal damage to major organs.

CHEMISTRY-A EUROPEAN JOURNAL (2021)

Article Chemistry, Multidisciplinary

Nanoprobes-Assisted Multichannel NIR-II Fluorescence Imaging-Guided Resection and Photothermal Ablation of Lymph Nodes

Xiaoxiao Fan et al.

Summary: This study introduces organic nanoprobes for lymph node imaging, proposing a multi-channel imaging modality and navigation system to prevent organ damage during surgery and provide precise treatment. The development of nanoprobes for fluorescence imaging-guided therapy offers a new basis for future precision surgery.

ADVANCED SCIENCE (2021)

Review Chemistry, Multidisciplinary

Conjugated Polymers: Optical Toolbox for Bioimaging and Cancer Therapy

Jinchao Wei et al.

Summary: Conjugated polymers have shown significant progress in bioimaging and cancer therapy, with advancements in optimizing optical properties and design strategies to overcome challenges. New applications in phototherapy of tumors and assistant drug therapy have also been explored, providing future directions for development.
Article Chemistry, Multidisciplinary

Add the Finishing Touch: Molecular Engineering of Conjugated Small Molecule for High-Performance AIE Luminogen in Multimodal Phototheranostics

Dan Li et al.

Summary: This study successfully developed a novel AIE luminogen IDT-TPE based on the IDT molecule, which showed enhanced fluorescence brightness and improved fluorescence imaging performance for mice tumors compared to IDT nanoparticles. The IDT-TPE nanoparticles exhibited near-infrared light-excitable features with a high epsilon and exceptional photothermal conversion efficiency, demonstrating unprecedented performance in multimodal phototheranostics.
Review Chemistry, Multidisciplinary

Recent Progress on NIR-II Photothermal Therapy

Yunguang Zhang et al.

Summary: Photothermal therapy is a promising treatment for cancer, with photothermal nanomaterials in the NIR-I region attracting attention. The use of light in the NIR-II region allows for deeper tissue penetration, higher radiation limits, and greater tissue tolerance, showing greater potential in photothermal conversion. This review highlights the photothermal properties of various nanomaterials in the NIR-II region and their application prospects in photothermal therapy, sparking interest in the field of cancer treatment and nanomedicine.

FRONTIERS IN CHEMISTRY (2021)

Review Chemistry, Multidisciplinary

Second near-infrared photothermal materials for combinational nanotheranostics

Cheng Xu et al.

Summary: Second near-infrared photothermal therapy (NIR-II PTT) has advantages of deeper penetration and less toxicity, but faces challenges of suboptimal photothermal conversion and limited therapeutic efficacy. To improve efficacy, multifunctional NIR-II photothermal inorganic or organic materials have been developed for combination with other therapeutic modalities.

CHEMICAL SOCIETY REVIEWS (2021)

Review Chemistry, Multidisciplinary

Structural and process controls of AIEgens for NIR-II theranostics

Shunjie Liu et al.

Summary: Aggregation-induced emission (AIE) is a cutting-edge technology for developing highly efficient NIR-II emitters and photothermal agents, with the optimization of multi-hierarchical structures and intramolecular motions balancing fluorescence imaging and photothermal therapy functions.

CHEMICAL SCIENCE (2021)

Review Chemistry, Multidisciplinary

Semiconducting Polymer Nanomaterials as Near-Infrared Photoactivatable Protherapeutics for Cancer

Jingchao Li et al.

ACCOUNTS OF CHEMICAL RESEARCH (2020)

Review Chemistry, Multidisciplinary

Two-Dimensional Nanomaterials for Photothermal Therapy

Shuang Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Review Biotechnology & Applied Microbiology

Recent Progress in NIR-II Contrast Agent for Biological Imaging

Jie Cao et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Review Chemistry, Multidisciplinary

Nanoparticle Phototherapy in the Era of Cancer Immunotherapy

Shiyi Zhou et al.

TRENDS IN CHEMISTRY (2020)

Article Chemistry, Physical

Quinonoid vs. aromatic structures of heteroconjugated polymers from oligomer calculations

Girishma Grover et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2020)

Review Chemistry, Multidisciplinary

Conjugated Polymer Nanoparticles for Imaging, Cell Activity Regulation, and Therapy

Yunxia Wang et al.

ADVANCED FUNCTIONAL MATERIALS (2019)

Review Nanoscience & Nanotechnology

Plasmonic polymer nanocomposites

Isabel Pastoriza-Santos et al.

NATURE REVIEWS MATERIALS (2018)

Article Multidisciplinary Sciences

Ultrafast bridge planarization in donor-π-acceptor copolymers drives intramolecular charge transfer

Palas Roy et al.

NATURE COMMUNICATIONS (2017)

Review Chemistry, Physical

Recent Progress in Cancer Thermal Therapy Using Gold Nanoparticles

Nardine S. Abadeer et al.

JOURNAL OF PHYSICAL CHEMISTRY C (2016)

Review Chemistry, Multidisciplinary

Functional Nanomaterials for Phototherapies of Cancer

Liang Cheng et al.

CHEMICAL REVIEWS (2014)

Article Chemistry, Organic

Near-infrared absorbing heterocyclic quinoid donors for organic solar cell devices

Emel Ay et al.

ORGANIC CHEMISTRY FRONTIERS (2014)

Article Chemistry, Multidisciplinary

Controlling Conformations of Conjugated Polymers and Small Molecules: The Role of Nonbonding Interactions

Nicholas E. Jackson et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

News Item Nanoscience & Nanotechnology

BIOIMAGING Second window for in vivo imaging

Andrew M. Smith et al.

NATURE NANOTECHNOLOGY (2009)

Article Multidisciplinary Sciences

Control of conformational and interpolymer effects in conjugated polymers

J Kim et al.

NATURE (2001)