期刊
CHEMICAL COMMUNICATIONS
卷 59, 期 17, 页码 2493-2496出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cc06645a
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In this study, the fluorescent probe ER-Nap-NBD was developed to detect H2S levels in solution and living systems (cells and zebrafish) using a naphthalimide fluorophore as the signal reporter, a 7-nitro-1,2,3-benzoxadiazole amine as the responsive moiety, and a sulfonamide part for endoplasmic reticulum targeting.
A crucial endogenous signaling chemical, hydrogen sulfide, is involved in many physiological actions. In this work, we created the fluorescent probe ER-Nap-NBD using a naphthalimide fluorophore as the signal reporter, a 7-nitro-1,2,3-benzoxadiazole amine as the responsive moiety, and a sulfonamide part for endoplasmic reticulum targeting. ER-Nap-NBD could be detected the H2S levels in solution and in living systems (cells and zebrafish).
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