Orange LED and cell fluorescence imaging of Mn2+ doped CsPbCl3 water-soluble nanocrystals with improved stability and optimized luminescence

Water-soluble Mn2+ doped CsPbCl3 nanocrystals coating by 6-aminocaproic acid (ACA) ligand were prepared by a simple ligand assisted reprecipitation method at room temperature. The CsPbCl3:Mn2+/ACA nanocrystals were almost cubic phase and had mean size of about 10 nm. Due to the coating and passivation of ACA, the CsPbCl3:Mn2+/ACA nanocrystals retained the initial fluorescence intensity of 20% after being dispersed in deionized water for 20 days. The orange LED device based on CsPbCl3:Mn2+/ACA nanocrystals were prepared with excellent luminescence properties. In the cytotoxicity test, even if the MCF-7 cells were cultured for 24 h at the concentration of CsPbCl3:Mn2+/ACA nanocrystals as high as 160 mu g center dot ml(-1), the cell survival rate was still 70%. Confocal fluorescent cell imaging results showed that the nanocrystals had remarkable fluorescent cell imaging effect even after 24 h. The synthesized CsPbCl3:Mn2+/ACA nanocrystals have nice water solubility, good water stability, low cytotoxicity and highly luminescence properties, and have great application potential in the field of orange LED and fluorescent probes.

Automated summary

Water-soluble Mn2+ doped CsPbCl3 nanocrystals coated with 6-aminocaproic acid (ACA) ligand were successfully prepared. The nanocrystals exhibited good water solubility, water stability, low cytotoxicity, and high luminescence properties, making them highly promising for applications in orange LED and fluorescent probes.