Specialized cells for building tissue bridges

Fang and colleagues provide a comprehensive transcriptomic analysis of the cell types occupying the interface between tendon and bone, the enthesis. They establish a framework for understanding enthesis maturation and identify a potent Gli1-lineage progenitor with clonogenicity and multipotency that improves enthesis healing in an adult injury model.

Automated summary

Fang et al. conducted a comprehensive transcriptomic analysis of the cell types in the enthesis, the interface between tendon and bone. They identified a potent Gli1-lineage progenitor with clonogenicity and multipotency, which improved enthesis healing in an adult injury model.