4.4 Article

Exposure-response analysis of Camidanlumab tesirine in patients with relapsed or refractory classical Hodgkin lymphoma and non-Hodgkin lymphoma

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Population pharmacokinetics analysis of camidanlumab tesirine in patients with relapsed or refractory Hodgkin lymphoma and non-Hodgkin lymphoma

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Summary: The purpose of this study was to develop a population pharmacokinetic (PPK) model to characterize the pharmacokinetics of camidanlumab tesirine (Cami) in patients with relapsed/refractory lymphoma. The final model obtained estimates of pharmacokinetic parameters and identified covariates that significantly affect Cami exposure.

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