期刊
BURNS
卷 49, 期 5, 页码 1003-1016出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.burns.2022.10.008
关键词
Curcumin nanoemulsion; Burn wound; Staphylococcus aureus; Antimicrobial activity
The review article focuses on the potential uses of curcumin nanoemulsion in the treatment and management of burn wounds. The poor solubility and low bioavailability of curcumin limit its effective use in managing bacterial infection related to burn wounds. The use of nano particle-based drug delivery systems, particularly nanoemulsion, can overcome these limitations and enhance the permeation ability of curcumin, making it a potential topical therapeutic agent in burn wound infection.
The review article concentrates on the potential uses of curcumin nanoemulsion in treatment and management of burn wound. Poor solubility and low bioavailability of curcumin limits the efficient and effective use of curcumin in management of bacterial infection related to burn wound. Nano particle based drug delivery system can be of great aid to solve this problem. Among this nanoemulsion is most favourable system due to its simplicity and low manufacturing cost. Nanoemulsion also enhances the skin permeation ability of curcumin and thus enhances its pharmacological efficacy specially as a potential antimicrobial agent, which can have applicability as a topical therapeutic agent in burn wound infection.
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