4.4 Article

Primary intraventricular synovial sarcoma of the brain with recurrence-case presentation

期刊

BMC NEUROLOGY
卷 22, 期 1, 页码 -

出版社

BMC
DOI: 10.1186/s12883-022-02975-w

关键词

Case report; Neuro-oncology; Synovial sarcoma

向作者/读者索取更多资源

This case report presents a recurrent primary intraventricular synovial sarcoma that was initially misdiagnosed as a haemangiopericytoma. The study highlights the importance of considering synovial sarcoma as part of the differential diagnosis for intraventricular spindle cell tumors in the brain.
Background: We report a case of recurrent primary intraventricular synovial sarcoma of the brain with no extracranial primary, initially reported as a haemangiopericytoma. We believe this is the first reported case of primary intraventricular synovial sarcoma at this site.Case presentation: A 27-year-old male presented to hospital with a new onset of seizures. Imaging revealed a left ventricular trigone mass with surrounding oedema. He underwent a left occipito-temporal craniotomy and resection with the histology reported as haemangiopericytoma. Resection was followed by adjuvant radiation treatment. Seven years later follow-up imaging revealed a 4 mm contrast enhancing lesion in the previous surgical bed. The patient underwent resection. Histological analysis of the recurrence revealed a spindle cell tumour with a SS18 gene rearrangement consistent with synovial sarcoma. Retrospective fluorescent in-situ hybridisation analysis of original histology also revealed a SS18 gene rearrangement consistent with a diagnosis of synovial sarcoma.Conclusion: Synovial sarcoma should be included as part of the differential diagnosis for patients presenting with intraventricular spindle cell tumours in the brain.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据