☆ 4.4 Article

JC virus-induced progressive multifocal leukoencephalopathy in a presumably healthy patient

BMC NEUROLOGY (2022)

BK virus-specificT cells for immunotherapy of progressive multifocal leukoencephalopathy: an open-label, single-cohort pilot study

Irene Cortese et al.

Summary: The study conducted an open-label, single-cohort pilot study in patients with progressive multifocal leukoencephalopathy. The results showed that generation of polyomavirus-specific T cells from healthy related donors is feasible and these cells can be safely used for adoptive immunotherapy of progressive multifocal leukoencephalopathy. The data provide support for this strategy as a potential life-saving therapy for some patients.

LANCET NEUROLOGY (2021)

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Editorial Material Clinical Neurology

Combined Treatment With Pembrolizumab and Allogenic BK Virus-Specific T Cells in Progressive Multifocal Leukoencephalopathy A Case Report

Rebecca Wicklein et al.

Summary: This case report highlights the potential effectiveness of combining pembrolizumab with virus-specific T cells in the treatment of progressive multifocal leukoencephalopathy (PML). The combination treatment resulted in clinical stabilization and improvements in cognitive and speech deficits, suggesting that further evaluation in future clinical trials is warranted.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2021)

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Review Clinical Neurology

Successful treatment of non-HIV progressive multifocal leukoencephalopathy: case report and literature review

Mai Hamaguchi et al.

JOURNAL OF NEUROLOGY (2020)

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Article Medicine, General & Internal

Pembrolizumab Treatment for Progressive Multifocal Leukoencephalopathy

Irene Cortese et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Article Medicine, Research & Experimental

Diagnosis of Sepsis with Cell-free DNA by Next-Generation Sequencing Technology in ICU Patients

Yun Long et al.

ARCHIVES OF MEDICAL RESEARCH (2016)

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Review Microbiology

Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain

Michael W. Ferenczy et al.

CLINICAL MICROBIOLOGY REVIEWS (2012)

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Article Microbiology

Identification and Characterization of Mefloquine Efficacy against JC Virus In Vitro

Margot Brickelmaier et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)

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JC virus-induced progressive multifocal leukoencephalopathy in a presumably healthy patient

相关参考文献

BK virus-specificT cells for immunotherapy of progressive multifocal leukoencephalopathy: an open-label, single-cohort pilot study

Combined Treatment With Pembrolizumab and Allogenic BK Virus-Specific T Cells in Progressive Multifocal Leukoencephalopathy A Case Report

Successful treatment of non-HIV progressive multifocal leukoencephalopathy: case report and literature review

Pembrolizumab Treatment for Progressive Multifocal Leukoencephalopathy

Diagnosis of Sepsis with Cell-free DNA by Next-Generation Sequencing Technology in ICU Patients

Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain

Identification and Characterization of Mefloquine Efficacy against JC Virus In Vitro

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