相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。FLT3 inhibitors in acute myeloid leukemia: ten frequently asked questions
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Eric I. Zimmerman et al.
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Da Zhang et al.
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A. J. Johnson et al.
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Kamil Paruch et al.
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DL Stirewalt et al.
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Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
Y Yamamoto et al.
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