Optimized culture conditions facilitate the estrone biodegradation ability and laccase activity of Spirulina CPCC-695

Endocrine disrupting compounds (EDCs) are emerging contaminants that persist and contaminate the environment. They mimic hormones, block hormones, or modulate their synthesis, metabolism, transport, and action, affecting living organisms and their progeny. Steroid hormones from exogenous sources like water bodies are important EDCs. Their biodegradation is an urgent global need. The present study is a preliminary work to maximize the estrone degradation potential of Spirulina CPCC-695 and study the effect of optimized conditions on its laccase activity. It was observed that the exponential phase culture at pH 10.0, 30 celcius, and 200 rpm of agitation speed resulted in the maximum growth, estrone degradation efficiency (93.12%), and highest laccase activity (74%) of Spirulina CPCC-695.

Automated summary

Endocrine disrupting compounds (EDCs) are persistent emerging contaminants that affect living organisms and their progeny. This study focused on optimizing conditions to maximize the estrone degradation potential of Spirulina CPCC-695 and investigate its laccase activity. The results showed that exponential phase culture at pH 10.0, 30 degrees Celsius, and 200 rpm agitation speed resulted in the highest growth, estrone degradation efficiency (93.12%), and laccase activity (74%) of Spirulina CPCC-695.