4.7 Article

MiR-133a-3p/Sirt1 epigenetic programming mediates hypercholesterolemia susceptibility in female offspring induced by prenatal dexamethasone exposure

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Low H3K27 acetylation of SF1 in PBMC: a biomarker for prenatal dexamethasone exposure-caused adrenal insufficiency of steroid synthesis in male offspring

Guanghui Chen et al.

Summary: This study revealed that prenatal dexamethasone exposure affects the morphology and function of the adrenal gland in male offspring rats. The activation of glucocorticoid receptor and the regulation of histone acetylation enzyme contribute to the inhibition of adrenal developmental genes, leading to adrenal insufficiency.

CELL BIOLOGY AND TOXICOLOGY (2023)

Article Pharmacology & Pharmacy

Prenatal dexamethasone exposure induces nonalcoholic fatty liver disease in male rat offspring via the miR-122/YY1/ACE2-MAS1 pathway

Heze Liu et al.

Summary: Studies have demonstrated that prenatal dexamethasone exposure can lead to nonalcoholic fatty liver disease in adult male rat offspring, with mechanisms including inhibition of miR-122 expression, increased YY1 expression, and inhibition of the ACE2-MAS1 signaling pathway, resulting in increased hepatic triglyceride synthesis and decreased oxidative function.

BIOCHEMICAL PHARMACOLOGY (2021)

Article Environmental Sciences

Maternally derived low glucocorticoid mediates adrenal developmental programming alteration in offspring induced by dexamethasone

Yawen Chen et al.

Summary: Prenatal dexamethasone exposure may continuously inhibit adrenal steroidogenic function in male offspring through the suppression of endogenous glucocorticoid-mediated adrenal developmental programming alteration.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

Article Pharmacology & Pharmacy

miR-148a/LDLR mediates hypercholesterolemia induced by prenatal dexamethasone exposure in male offspring rats

Li Li et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2020)

Article Pharmacology & Pharmacy

Glucocorticoid programming mechanism for hypercholesterolemia in prenatal ethanol-exposed adult offspring rats

Shuwei Hu et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2019)

Review Immunology

Developmental origin and sex-specific risk for infections and immune diseases later in life

Dimitra E. Zazara et al.

SEMINARS IN IMMUNOPATHOLOGY (2019)

Review Biochemistry & Molecular Biology

The role of microRNAs in glucocorticoid action

Sally A. Clayton et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Genetics & Heredity

gga-mir-133a-3p Regulates Myoblasts Proliferation and Differentiation by Targeting PRRX1

Lijin Guo et al.

FRONTIERS IN GENETICS (2018)

Review Biochemistry & Molecular Biology

MicroRNAs and lipid metabolism

Binod Aryal et al.

CURRENT OPINION IN LIPIDOLOGY (2017)

Article Endocrinology & Metabolism

Transcriptional and Metabolic Effects of Glucocorticoid Receptor α and β Signaling in Zebrafish

Antonia Chatzopoulou et al.

ENDOCRINOLOGY (2015)

Article Biochemistry & Molecular Biology

Effect of testosterone deficiency on cholesterol metabolism in pigs fed a high-fat and high-cholesterol diet

Zhaowei Cai et al.

LIPIDS IN HEALTH AND DISEASE (2015)

Article Obstetrics & Gynecology

Fetal Programming, Epigenetics, and Adult Onset Disease

Robert H. Lane

CLINICS IN PERINATOLOGY (2014)

Review Endocrinology & Metabolism

Glucocorticoids and fetal programming part 1: outcomes

Vasilis G. Moisiadis et al.

NATURE REVIEWS ENDOCRINOLOGY (2014)

Review Endocrinology & Metabolism

Glucocorticoids and fetal programming part 2: mechanisms

Vasilis G. Moisiadis et al.

NATURE REVIEWS ENDOCRINOLOGY (2014)

Review Gastroenterology & Hepatology

New compounds able to control hepatic cholesterol metabolism: Is it possible to avoid statin treatment in aged people?

Laura Trapani et al.

WORLD JOURNAL OF HEPATOLOGY (2013)

Article Obstetrics & Gynecology

The origin of fetal sterols in second-trimester amniotic fluid: endogenous synthesis or maternal-fetal transport?

Maria E. Baardman et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2012)

Article Biochemistry & Molecular Biology

The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD+

Zachary Gerhart-Hines et al.

MOLECULAR CELL (2011)

Article Biochemistry & Molecular Biology

Dose translation from animal to human studies revisited

Shannon Reagan-Shaw et al.

FASEB JOURNAL (2008)

Review Medicine, Research & Experimental

Mechanisms underlying the role of glucocorticoids in the early life programming of adult disease

Amanda J. Drake et al.

CLINICAL SCIENCE (2007)

Review Pharmacology & Pharmacy

Synthetic glucocorticoids: Antenatal administration and long-term implications

DM Sloboda et al.

CURRENT PHARMACEUTICAL DESIGN (2005)

Review Endocrinology & Metabolism

Non-genomic actions of sex steroid hormones

T Simoncini et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2003)

Article Obstetrics & Gynecology

Antenatal corticosteroids: the good, the bad and the unknown

JP Newnham et al.

CURRENT OPINION IN OBSTETRICS & GYNECOLOGY (2002)