期刊
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
卷 87, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.bpobgyn.2022.102307
关键词
Cumulative live birth rate; Ovarian stimulation; IVF; Oocytes
The literature regarding the association between the number of oocytes retrieved and the cumulative live birth rate (CLBR) is conflicting. Some studies suggest a continuous increase in CLBR with more oocytes retrieved, while others find a plateau. The association between oocyte number and CLBR varies according to patients' age.
The available literature is controversial regarding the association between the number of oocytes retrieved and the cumulative live birth rate (CLBR). Although some authors report a continuous increase in the CLBR with the number of oocytes retrieved, others have found a plateau. A systematic review was conducted, including all eligible studies published until June 2022, to determine the optimal number of oocytes retrieved to maximize the CLBR. We found a positive association between the number of oocytes and the CLBR. However, this association varies according to patients' age. While in patients younger than 35 years, little benefit is derived from increasing the number of oocytes above 25 -30, in patients older than 35 years, the number of oocytes seems to improve the CLBR until the extreme of reproductive age is reached. In women aged 44 years or older, the CLBR will be consistently low, independent of the number of oocytes retrieved. (c) 2023 Elsevier Ltd. All rights reserved.
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