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Membrane Atg8ylation, stress granule formation, and MTOR regulation during lysosomal damage

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Article Cell Biology

Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage

Jingyue Jia et al.

Summary: Lysosomal damage induces the formation of stress granules and coordinates mTOR inactivation through the process of membrane atg8ylation. This process is effective against various lysosomal damaging agents.

JOURNAL OF CELL BIOLOGY (2022)