4.4 Article

An Intensivist-Led Extracorporeal Membrane Oxygenation Program: Design, Implementation, and Outcomes of the First Five Years

期刊

ASAIO JOURNAL
卷 69, 期 5, 页码 451-459

出版社

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MAT.0000000000001870

关键词

intensivist; critical care; extracorporeal membrane oxygenation; extracorporeal life support; cannulation; extracorporeal cardiopulmonary resuscitation; ECMO; ECPR; ECLS

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This study retrospectively analyzed the development, implementation, and outcomes of an intensivist-led adult extracorporeal life support (ECLS) program at the University of New Mexico Hospital. The results showed that the intensivist-led ECLS program was successful, with a survival rate comparable to the literature, reaching 56% in the non-ECPR V-A group and 66.7% in the COVID-19-negative V-V group.
We describe the development, implementation, and outcomes of an intensivist-led adult extracorporeal life support (ECLS) program using intensivists both to perform venovenous (V-V), venoarterial (V-A), and extracorporeal cardiopulmonary resuscitation (ECPR) cannulations, and to manage patients on ECLS throughout their ICU course. All adults supported with ECLS at the University of New Mexico Hospital (UNMH) from February 1, 2017 to December 31, 2021 were retrospectively analyzed. A total of 203 ECLS cannulations were performed in 198 patients, including 116 V-A cannulations (including 65 during ECPR) and 87 V-V cannulations (including 38 in patients with COVID-19). UNMH intensivists performed 195 cannulations, with 9 cannulation complications. Cardiothoracic surgeons performed 8 cannulations. Overall survival to hospital discharge or transfer was 46.5%. Survival was 32.3% in the ECPR group and 56% in the non-ECPR V-A group. In the V-V cohort, survival was 66.7% in the COVID-19-negative patients and 34.2% in the COVID-19-positive patients. This large series of intensivist-performed ECLS cannulations-including V-A, V-V, and ECPR modalities-demonstrates the successful implementation of a comprehensive intensivist-led ECLS program. With outcomes comparable to those in the literature, our program serves as a model for the initiation and development of ECLS programs in settings with limited access to local subspecialty cardiothoracic surgical services.

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