相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Monocarboxylate transporter 4 inhibition potentiates hepatocellular carcinoma immunotherapy through enhancing T cell infiltration and immune attack
Yuan Fang et al.
HEPATOLOGY (2023)
Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
Shogo Kumagai et al.
CANCER CELL (2022)
In Vivo Anticancer Activity of AZD3965: A Systematic Review
Ana Silva et al.
MOLECULES (2022)
Systematic Review of Gossypol/AT-101 in Cancer Clinical Trials
Olga Renner et al.
PHARMACEUTICALS (2022)
The lactate sensor GPR81 regulates glycolysis and tumor growth of breast cancer
Shota Ishihara et al.
SCIENTIFIC REPORTS (2022)
Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells
Lianhong Pan et al.
PHARMACOLOGICAL RESEARCH (2022)
Lactate: A regulator of immune microenvironment and a clinical prognosis indicator in colorectal cancer
Daoqi Zhu et al.
FRONTIERS IN IMMUNOLOGY (2022)
Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates
Nan Wang et al.
CELL (2021)
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
Ahmad A. Cluntun et al.
CELL METABOLISM (2021)
Discovery of a novel lactate dehydrogenase tetramerization domain using epitope mapping and peptides
Leopold Thabault et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid
McLane J. Watson et al.
NATURE (2021)
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions
Minfeng Ying et al.
REDOX BIOLOGY (2021)
The cross-talk between tumor cells and activated fibroblasts mediated by lactate/BDNF/TrkB signaling promotes acquired resistance to anlotinib in human gastric cancer
Zhijian Jin et al.
REDOX BIOLOGY (2021)
Designed β-Hairpins Inhibit LDH5 Oligomerization and Enzymatic Activity
Ferran Nadal-Bufi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Phase I expansion study of the first-in-class monocarboxylate transporter 1 (MCT1) inhibitor AZD3965 in patients with diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL).
Sarah E. R. Halford et al.
JOURNAL OF CLINICAL ONCOLOGY (2021)
The macrophage odorant receptor Olfr78 mediates the lactate-induced M2 phenotype of tumor-associated macrophages
Sri Murugan Poongkavithai Vadevoo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas
Emmanuela N. Bonglack et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Lactate dehydrogenase A-dependent aerobic glycolysis promotes natural killer cell anti-viral and anti-tumor function
Sam Sheppard et al.
CELL REPORTS (2021)
Lactate Modulates Cellular Metabolism Through Histone Lactylation-Mediated Gene Expression in Non-Small Cell Lung Cancer
Jun Jiang et al.
FRONTIERS IN ONCOLOGY (2021)
Expression and Clinical Significance of Lactate Dehydrogenase A in Colon Adenocarcinoma
Yutong Wang et al.
FRONTIERS IN ONCOLOGY (2021)
Identification of the first highly selective inhibitor of human lactate dehydrogenase B
Sachio Shibata et al.
SCIENTIFIC REPORTS (2021)
Histone lactylation drives oncogenesis by facilitating m6A reader protein YTHDF2 expression in ocular melanoma
Jie Yu et al.
GENOME BIOLOGY (2021)
Monocarboxylate transporters in cancer
Valery L. Payen et al.
MOLECULAR METABOLISM (2020)
A lactate-induced Snail/STAT3 pathway drives GPR81 expression in lung cancer cells
Qiang Xie et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2020)
A case of malignant hyperlactaemic acidosis appearing upon treatment with the mono-carboxylase transporter 1 inhibitor AZD3965
Rosie McNeillis et al.
BRITISH JOURNAL OF CANCER (2020)
Metabolic heterogeneity confers differences in melanoma metastatic potential
Alpaslan Tasdogan et al.
NATURE (2020)
Monocarboxylate Transporters (SLC16): Function, Regulation, and Role in Health and Disease
Melanie A. Felmlee et al.
PHARMACOLOGICAL REVIEWS (2020)
Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells
Sicheng Fu et al.
NATURE COMMUNICATIONS (2020)
Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy
Nobu Oshima et al.
CELL REPORTS (2020)
Interrogating the Lactate Dehydrogenase Tetramerization Site Using (Stapled) Peptides
Leopold Thabault et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
A randomized, double-blind, placebo-controlled study of B-cell lymphoma 2 homology 3 mimetic gossypol combined with docetaxel and cisplatin for advanced non-small cell lung cancer with high expression of apurinic/apyrimidinic endonuclease 1
Yuxiao Wang et al.
INVESTIGATIONAL NEW DRUGS (2020)
Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism
Cassidy C. Daw et al.
CELL (2020)
ALKBH5 regulates anti-PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment
Na Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer
Lisa M. Becker et al.
CELL REPORTS (2020)
Lactate-Modulated Immunosuppression of Myeloid-Derived Suppressor Cells Contributes to the Radioresistance of Pancreatic Cancer
Xuguang Yang et al.
CANCER IMMUNOLOGY RESEARCH (2020)
Lactate Limits T Cell Proliferation via the NAD(H) Redox State
William J. Quinn et al.
CELL REPORTS (2020)
HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications
Youbo Zhao et al.
CELL REPORTS (2020)
Lactate: the ugly duckling of energy metabolism
Joshua D. Rabinowitz et al.
NATURE METABOLISM (2020)
Oxidized ATM-mediated glycolysis enhancement in breast cancer-associated fibroblasts contributes to tumor invasion through lactate as metabolic coupling
Kexin Sun et al.
EBIOMEDICINE (2019)
Oncogenic KRAS signaling activates mTORC1 through COUP-TFII-mediated lactate production
Jun-Kyu Byun et al.
EMBO REPORTS (2019)
Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS
Weina Zhang et al.
CELL (2019)
A phase II study of the orally administered negative enantiomer of gossypol (AT-101), a BH3 mimetic, in patients with advanced adrenal cortical carcinoma
Hao Xie et al.
INVESTIGATIONAL NEW DRUGS (2019)
Lactate Induces Pro-tumor Reprogramming in Intratumoral Plasmacytoid Dendritic Cells
Deblina Raychaudhuri et al.
FRONTIERS IN IMMUNOLOGY (2019)
Increased proton-sensing receptor GPR4 signalling promotes colorectal cancer progression by activating the hippo pathway
Minhao Yu et al.
EBIOMEDICINE (2019)
Metabolic regulation of gene expression by histone lactylation
Di Zhang et al.
NATURE (2019)
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
Kathrin Renner et al.
CELL REPORTS (2019)
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts
Tushar D. Bhagat et al.
ELIFE (2019)
Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches
Karen G. de la Cruz-Lopez et al.
FRONTIERS IN ONCOLOGY (2019)
Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression
Na Liu et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Lactate modulates CD4+ T-cell polarization and induces an immunosuppressive environment, which sustains prostate carcinoma progression via TLR8/miR21 axis
G. Comito et al.
ONCOGENE (2019)
Stromal-epithelial lactate shuttle induced by tumor-derived interleukin-1β promotes cell proliferation in oral squamous cell carcinoma
Jie Wu et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)
Downregulation of Membrane Trafficking Proteins and Lactate Conditioning Determine Loss of Dendritic Cell Function in Lung Cancer
Nicoletta Caronni et al.
CANCER RESEARCH (2018)
Tumor-derived lactate induces M2 macrophage polarization via the activation of the ERK/STAT3 signaling pathway in breast cancer
Xianmin Mu et al.
CELL CYCLE (2018)
Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16INK4a inactivation
Xiangrui Li et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Cancer-associated fibroblasts enhance tumor 18F-FDG uptake and contribute to the intratumor heterogeneity of PET-CT
Chengfang Shangguan et al.
THERANOSTICS (2018)
Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo
Kevin D. Courtney et al.
CELL METABOLISM (2018)
Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
Maria Apicella et al.
CELL METABOLISM (2018)
Double genetic disruption of lactate dehydrogenases A and B is required to ablate the Warburg effect restricting tumor growth to oxidative metabolism
Masa Zdralevic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance
Maria Quanz et al.
MOLECULAR CANCER THERAPEUTICS (2018)
Downregulation of MCT4 for lactate exchange promotes the cytotoxicity of NK cells in breast carcinoma
Yaping Long et al.
CANCER MEDICINE (2018)
Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
Toszka Bohn et al.
NATURE IMMUNOLOGY (2018)
ME1 promotes basal-like breast cancer progression and associates with poor prognosis
Ruocen Liao et al.
SCIENTIFIC REPORTS (2018)
Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD plus Depletion in Cancer Cells
Don Benjamin et al.
CELL REPORTS (2018)
Prognostic Significance of Serum Lactic Acid, Lactate Dehydrogenase, and Albumin Levels in Patients with Metastatic Colorectal Cancer
Yan Wei et al.
BIOMED RESEARCH INTERNATIONAL (2018)
Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy
Yangbo Feng et al.
CANCER MEDICINE (2018)
Monocarboxylate transporter 1 is a key player in glioma-endothelial cell crosstalk
Vera Miranda-Goncalves et al.
MOLECULAR CARCINOGENESIS (2017)
Glucose feeds the TCA cycle via circulating lactate
Sheng Hui et al.
NATURE (2017)
Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells
J. Feng et al.
ONCOGENE (2017)
Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism
Tao Shan et al.
ONCOLOGY REPORTS (2017)
Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis
Peiwen Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors
Vincent F. Van Hee et al.
ONCOTARGET (2017)
Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression
Dillon M. Voss et al.
SCIENTIFIC REPORTS (2017)
Suppression of FIP200 and autophagy by tumor-derived lactate promotes naive T cell apoptosis and affects tumor immunity
Houjun Xia et al.
SCIENCE IMMUNOLOGY (2017)
Lactate Metabolism in Human Lung Tumors
Brandon Faubert et al.
CELL (2017)
Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments
Alessia Angelin et al.
CELL METABOLISM (2017)
Stimulation of lactate receptor (HCAR1) affects cellular DNA repair capacity
Waldemar Wagner et al.
DNA REPAIR (2017)
Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy
Shari Pilon-Thomas et al.
CANCER RESEARCH (2016)
Metabolic coupling in urothelial bladder cancer compartments and its correlation to tumor aggressiveness
Julieta Afonso et al.
CELL CYCLE (2016)
Lactate promotes glutamine uptake and metabolism in oxidative cancer cells
Jhudit Perez-Escuredo et al.
CELL CYCLE (2016)
Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer
Lucie Brisson et al.
CANCER CELL (2016)
Metabolic Heterogeneity in Human Lung Tumors
Christopher T. Hensley et al.
CELL (2016)
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
Almut Brand et al.
Cell Metabolism (2016)
Lactate as a predictive marker for tumor recurrence in patients with head and neck squamous cell carcinoma (HNSCC) post radiation: a prospective study over 15 years
Sebastian Blatt et al.
CLINICAL ORAL INVESTIGATIONS (2016)
Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition
Aaron Boudreau et al.
NATURE CHEMICAL BIOLOGY (2016)
Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity
Ruth Eichner et al.
NATURE MEDICINE (2016)
Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
Min Peng et al.
SCIENCE (2016)
G-protein-coupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion
Yu Jin Lee et al.
ONCOTARGET (2016)
Targeting Metabolic Symbiosis to Overcome Resistance to Anti-angiogenic Therapy
Laura Pisarsky et al.
CELL REPORTS (2016)
ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer
Sunghee Park et al.
CELL REPORTS (2016)
Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone
Wing Yin Cheng et al.
ELIFE (2016)
The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer
Zhibin Jing et al.
PLOS ONE (2016)
Elevated lactic acid is a negative prognostic factor in metastatic lung cancer
Panagiotis J. Vlachostergios et al.
CANCER BIOMARKERS (2015)
A Lactate-Induced Response to Hypoxia
Dong Chul Lee et al.
CELL (2015)
L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation
Waldemar Wagner et al.
CELL COMMUNICATION AND SIGNALING (2015)
Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation
Daoxiang Zhang et al.
CELL REPORTS (2015)
Lactate does not activate NF-κB in oxidative tumor cells
Vincent F. Van Hee et al.
FRONTIERS IN PHARMACOLOGY (2015)
A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer
Nelma Pertega-Gomes et al.
BMC CANCER (2014)
Cell Surface Lactate Receptor GPR81 Is Crucial for Cancer Cell Survival
Christina L. Roland et al.
CANCER RESEARCH (2014)
Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells
Han Xie et al.
CELL METABOLISM (2014)
Epidermal Growth Factor Receptor ( EGFR) Signaling Regulates Global Metabolic Pathways in EGFR-mutated Lung Adenocarcinoma
Hideki Makinoshima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
Oscar R. Colegio et al.
NATURE (2014)
Acidity Generated by the Tumor Microenvironment Drives Local Invasion
Veronica Estrella et al.
CANCER RESEARCH (2013)
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
Chih-Hao Chang et al.
CELL (2013)
Lactate Dehydrogenase B Is Required for the Growth of KRAS-Dependent Lung Adenocarcinomas
Mark L. McCleland et al.
CLINICAL CANCER RESEARCH (2013)
Small-molecule inhibitors of human LDH5
Carlotta Granchi et al.
FUTURE MEDICINAL CHEMISTRY (2013)
Targeting lactate metabolism for cancer therapeutics
Joanne R. Doherty et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
Jaekyoung Son et al.
NATURE (2013)
Catabolism of Exogenous Lactate Reveals It as a Legitimate Metabolic Substrate in Breast Cancer
Kelly M. Kennedy et al.
PLOS ONE (2013)
Immunosuppressive properties of a series of novel inhibitors of the monocarboxylate transporter MCT-1
Clara Pahlman et al.
TRANSPLANT INTERNATIONAL (2013)
Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells
Julia Billiard et al.
CANCER & METABOLISM (2013)
Monocarboxylic Acid Transport
Andrew P. Halestrap
COMPREHENSIVE PHYSIOLOGY (2013)
An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast Cancer
Mark L. McCleland et al.
CANCER RESEARCH (2012)
Pre-clinical targeting of the metabolic phenotype of lymphoma by AZD3965, a selective inhibitor of monocarboxylate transporter 1 (MCT1)
Susan E. Critchlow et al.
CANCER RESEARCH (2012)
Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes
Arianna Calcinotto et al.
CANCER RESEARCH (2012)
Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
Tania Fiaschi et al.
CANCER RESEARCH (2012)
Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
Haoqiang Ying et al.
CELL (2012)
Galloflavin (CAS 568-80-9): A Novel Inhibitor of Lactate Dehydrogenase
Marcella Manerba et al.
CHEMMEDCHEM (2012)
Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment
Yanique L. Rattigan et al.
EXPERIMENTAL CELL RESEARCH (2012)
Metabolism of [U-13C]glucose in human brain tumors in vivo
Elizabeth A. Maher et al.
NMR IN BIOMEDICINE (2012)
Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression
Tom Latham et al.
NUCLEIC ACIDS RESEARCH (2012)
Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis
Pierre Sonveaux et al.
PLOS ONE (2012)
Lactate Activates HIF-1 in Oxidative but Not in Warburg-Phenotype Human Tumor Cells
Christophe J. De Saedeleer et al.
PLOS ONE (2012)
Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF-κB/IL-8 Pathway that Drives Tumor Angiogenesis
Frederique Vegran et al.
CANCER RESEARCH (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Stromal-epithelial metabolic coupling in cancer: Integrating autophagy and metabolism in the tumor microenvironment
Ubaldo E. Martinez-Outschoorn et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells
Carlotta Granchi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
A Phase II Study of AT-101 (Gossypol) in Chemotherapy-Sensitive Recurrent Extensive-Stage Small Cell Lung Cancer
Maria Q. Baggstrom et al.
JOURNAL OF THORACIC ONCOLOGY (2011)
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors
Renaud Le Floch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Inhibition kinetics of NAD-linked enzymes by gossypol acetic acid
M. Ikeda
ANDROLOGIA (2010)
AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10
Matthew J. Ovens et al.
BIOCHEMICAL JOURNAL (2010)
Immune Stimulatory Receptor CD40 Is Required for T-Cell Suppression and T Regulatory Cell Activation Mediated by Myeloid-Derived Suppressor Cells in Cancer
Ping-Ying Pan et al.
CANCER RESEARCH (2010)
Ketones and lactate fuel tumor growth and metastasis Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
Gloria Bonuccelli et al.
CELL CYCLE (2010)
An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81
Kashan Ahmed et al.
CELL METABOLISM (2010)
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
Mikala Egeblad et al.
DEVELOPMENTAL CELL (2010)
The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor
Yuichiro Ihara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
Anne Le et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
An Open-Label, Multicenter, Phase I/II Study of Single-Agent AT-101 in Men with Castrate-Resistant Prostate Cancer
Glenn Liu et al.
CLINICAL CANCER RESEARCH (2009)
Myeloid Derived Suppressor Cells Inhibit Natural Killer Cells in Patients with Hepatocellular Carcinoma via the NKp30 Receptor
Bastian Hoechst et al.
HEPATOLOGY (2009)
Cell-cell and intracellular lactate shuttles
George A. Brooks
JOURNAL OF PHYSIOLOGY-LONDON (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
Pierre Sonveaux et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Recommendations on the use of F-18-FDG PET in oncology
James W. Fletcher et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles
Ilaria Giusti et al.
NEOPLASIA (2008)
The specific monocarboxylate transporter-1 (MCT-1) inhibitor, AR-C117977, induces donor-specific suppression, reducing acute and chronic allograft rejection in the rat
Henrik Ekberg et al.
TRANSPLANTATION (2007)
Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer
Srinivas Nagaraj et al.
NATURE MEDICINE (2007)
Inhibitory effect of tumor cell-derived lactic acid on human T cells
Karin Fischer et al.
BLOOD (2007)
Inhibitory effects of statins on human monocarboxylate transporter 4
Masaki Kobayashi et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1α-dependent mechanism
MS Ullah et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Tumor-derived lactic acid modulates dendritic cell activation and antigen expression
E Gottfried et al.
BLOOD (2006)
Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma.
MI Koukourakis et al.
CANCER RESEARCH (2006)
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1
HS Lu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Acidic extracellular pH induces matrix metalloproteinase-9 expression in mouse metastatic melanoma cells through the phospholipase D-mitogen-activated protein kinase signaling
Y Kato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Increased lactate/pyruvate ratio augments blood flow in physiologically activated human brain
MA Mintun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
分享论文
