☆ 4.8 Article

A Telomerase-Assisted Strategy for Regeneration of DNA Nanomachines in Living Cells

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Chemistry, Multidisciplinary

Biomimetic Nanoerythrosome-Coated Aptamer-DNA Tetrahedron/Maytansine Conjugates: pH-Responsive and Targeted Cytotoxicity for HER2-Positive Breast Cancer

Wenjuan Ma et al.

Summary: DNA materials have been used as nanocarriers for targeted cancer therapy, but their short half-life and low bioavailability hinder their clinical translation. This study developed a HER2-targeted DNA-aptamer-modified DNA tetrahedron/DM1 conjugate, and applied a biomimetic camouflage to enhance drug delivery and tumor-stimulated drug release. The hybrid erythrosome-based nanoparticles exhibited superior inhibition of HER2-positive cancer.

ADVANCED MATERIALS (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Insights into nucleic acid-based self-assembling nanocarriers for targeted drug delivery and controlled drug release

Keren Chen et al.

Summary: This review systematically summarizes the strategies of nucleic acid-based self-assembling nanocarriers (NASNs) in drug delivery and their broad applications.

JOURNAL OF CONTROLLED RELEASE (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

CRISPR System-Linked Self-Assembling Nanoplatforms for Inspection and Screening of Gastric Cancer Stem Cells

Shan Huang et al.

Summary: The self-assembled heterodimer A-CCA is designed to identify and screen gastric cancer stem cells (GCSCs) with high specificity and sensitivity. This nanoplatform can recognize dual-targets in GCSCs and enable in situ examination and screening of these cells, leading to the development of CSC-targeted drugs in vivo.

SMALL (2022)

添加到收藏夹

Review Nanoscience & Nanotechnology

Nucleic acid-based electrochemical biosensor: Recent advances in probe immobilization and signal amplification strategies

Krishna Thapa et al.

Summary: DNA-based electrochemical biosensors have attracted scientific and clinical interests due to their specificity and fast response time. Strategies for DNA probe immobilization and signal amplification play a critical role in achieving high detection sensitivity. Advancements in nanotechnology and biochemistry show promise in the development of portable sensing devices for clinical testing.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ultrasensitive Electrochemical Detection of Mutated Viral RNAs with Single-Nucleotide Resolution Using a Nanoporous Electrode Array (NPEA)

Jinho Yoon et al.

Summary: The detection of nucleic acids and their mutation derivatives is crucial in biomedical science and applications. Current nucleic acid biosensors often require pretreatment processes and cannot detect specific sequence mutations. To overcome these limitations, a novel electrochemical nano-biosensing system was developed using metal ion intercalation and a gold nanoporous electrode array. This system enables sensitive detection of viral RNA, determination of viral mutation occurrence, and multiplexed detection of multiple RNA targets simultaneously.

ACS NANO (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

DNA-Based Nanoarchitectures as Eminent Vehicles for Smart Drug Delivery Systems

Makoto Komiyama et al.

Summary: This review discusses recent advances in drug delivery systems (DDS) using DNA nanoarchitectures as drug carriers, showcasing the controlled release of drugs through disassembly and the use of appropriate stimuli for regulating DDS processes to enhance therapy.

ADVANCED FUNCTIONAL MATERIALS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Self-Serviced-Track 3D DNA Walker for Ultrasensitive Detection of Tumor Exosomes by Glycoprotein Profiling

Huizhen Wang et al.

Summary: The STDW, which utilizes target Exos as a 3D track for semi-autonomous running, enables wash-free detection of low-concentration tumor Exos. The method demonstrates high selectivity, sensitivity, and accuracy in clinical sample analysis, offering potential for early cancer diagnosis and postoperative response prediction.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

添加到收藏夹

Article Biophysics

Ultrasensitive photoelectrochemical aptasensor for detecting telomerase activity based on Ag2S/Ag decorated ZnIn2S4/C3N4 3D/2D Z-scheme heterostructures and amplified by Au/Cu2+-boron-nitride nanozyme

Jian-Hong Zhu et al.

Summary: In this study, a novel aptasensor was designed for ultra-sensitive detection of telomerase activity by utilizing Au nanoparticles and Cu2+-modified boron nitride nanosheets as nanozyme. By using Ag2S/Ag nanoparticles decorated ZnIn2S4/C3N4 Z-scheme heterostructures and PEC signal amplification strategy, an aptasensor with a wide linear range and low detection limit was successfully developed.

BIOSENSORS & BIOELECTRONICS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

SARS-CoV-2 monitoring by automated target-driven molecular machine-based engineering

Zhenqiang Fan et al.

Summary: In this study, an automated DNA molecular machine was built on Ti3C2/polyethyleneimine-Ru(dcbpy)(3)(2+)@Au composite for nucleic acid-structured electrochemiluminescence in medical diagnostics. By transducing the target concentration information to the electrochemiluminescence signal based on DNA hybridization calculations, the sensitivity and accuracy of detection were enhanced. The advantage of this molecular machine is the reduction of tedious operating steps.

ENVIRONMENTAL CHEMISTRY LETTERS (2022)

添加到收藏夹

Review Nanoscience & Nanotechnology

Multimodules integrated functional DNA nanomaterials for intelligent drug delivery

Yunhua Guo et al.

Summary: DNA, as an emerging building block for functional biomaterials, has attracted attention in constructing intelligent nanomaterials with predictable nanostructure and adjustable functions. Functionalization modules in DNA nanomaterial construction are divided into targeting, responsive, and therapeutic modules, with representative nanomaterials like DNA nanogel and DNA origami used in drug delivery applications. Challenges in transitioning DNA materials to clinical applications are discussed, with the potential for further development of intelligent materials for real-world applications emphasized.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2022)

添加到收藏夹

Article Multidisciplinary Sciences

TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance

Valentina Buemi et al.

Summary: Researchers have found that the trimethylguanosine capping of the RNA component of the human telomerase complex plays an important role in directing telomere maintenance and suppressing the ALT pathway in cancer cells.

NATURE COMMUNICATIONS (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

DNA Walkers for Biosensing Development

Lu Song et al.

Summary: DNA nanomaterials, with the ability to design arbitrary shapes and controllable motions, have been widely used to construct diverse nanomachines. Among them, DNA walkers are popular nanodevices with ingenious design and flexible function, showing great potential in biosensing applications.

ADVANCED SCIENCE (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Multiply Guaranteed and Successively Amplified Activation of a Catalytic DNA Machine for Highly Efficient Intracellular Imaging of MicroRNA

Shanshan Yu et al.

Summary: In this study, a high-contrast in vivo imaging of microRNA (miRNA) was achieved by integrating an entropy-driven catalytic DNA amplification machine with on-site amplified substrate exposure procedure. The undesired signal leakage was eliminated by grafting substrate subunits into an auxiliary DNA polymerization amplification accessory. The intact machine-propelling functions were restored by cell-specific mRNA, ensuring the high specificity of on-site amplified miRNA imaging. This intelligent machinery shows great potential in biomedical diagnosis.

SMALL (2022)

添加到收藏夹

Article Engineering, Biomedical

A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma

Devora Najjar et al.

Summary: A 3D-printed lab-on-a-chip has been developed for rapid and accurate detection of SARS-CoV-2 RNA and antibodies, providing a convenient method for determining immune status in individuals.

NATURE BIOMEDICAL ENGINEERING (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Endogenous mRNA Triggered DNA-Au Nanomachine for In Situ Imaging and Targeted Multimodal Synergistic Cancer Therapy

Sha Yu et al.

Summary: The study developed a nanomachine for breast cancer treatment, which can be activated inside cells for in situ imaging and targeted synergistic therapy, including releasing fluorophores and aggregating AuNPs for imaging, suppressing survivin expression, and photothermal therapy.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Organelle-Specific Photoactivation of DNA Nanosensors for Precise Profiling of Subcellular Enzymatic Activity

Yulei Shao et al.

Summary: The technology allows for in situ imaging of enzymatic activity in specific organelles through controlled localization and photoactivation, leading to improved subcellular resolution.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Cooperatively Activatable, DNA-based Fluorescent Reporter for Imaging of Correlated Enzymatic Activities

Zetan Fan et al.

Summary: The study introduces a DNA-based fluorescent reporter that can detect the activity of two enzymes, TE and APE1, which are crucial for tumor progression and drug treatment. The system allows for in vivo imaging of the enzymatic activities and specific tumor imaging through a dual lock-and-key strategy.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Near-Infrared Light Controllable DNA Walker Driven by Endogenous Adenosine Triphosphate for in Situ Spatiotemporal Imaging of Intracellular MicroRNA

Mingqiang Ye et al.

Summary: A NIR-photoactivatable DNA walker system powered by endogenous ATP was developed for in situ miRNA imaging in living cells with high spatial and temporal resolution. The system utilized UCNPs as carriers and transducers, showing stability and low fluorescent background. This smart system based on NIR light initiated DNA walker successfully achieved precise spatiotemporal control in living cells and has been applied for in situ miRNA imaging with high resolution.

ACS NANO (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Activating a DNA Nanomachine via Computation across Cancer Cell Membranes for Precise Therapy of Solid Tumors

Yue Zhang et al.

Summary: By modifying DNA strands on upconversion nanoparticles, a transmembrane DNA logical computation strategy is designed to activate a DNA nanomachine only in cancer cells from a complex solid tumor microenvironment, achieving highly precise therapy.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Amplification-Free and Mix-and-Read Analysis of Multiplexed MicroRNAs on a Single Plasmonic Microbead

Xiaohui Lu et al.

Summary: In this study, a single microbead covered with a plasmonic layer is used as a microreactor for multiplexed miRNA analysis without nucleic acid amplification. The S9.6 antibody and SERS reporter gold nanoparticle pool are employed for specific detection of target miRNAs, achieving high-precision sensing of sub-pM target miRNAs.

NANO LETTERS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

A core-brush 3D DNA nanostructure: the next generation of DNA nanomachine for ultrasensitive sensing and imaging of intracellular microRNA with rapid kinetics

Lingqi Kong et al.

Summary: A highly loaded and integrated core-brush three-dimensional (3D) DNA nanostructure was constructed for rapid and sensitive intracellular microRNA (miRNA) imaging and sensing. The specific walking range for the DNA walking arm (DA) was provided to avoid invalid and random self-walking, significantly improving the executive ability of the core-brush 3D DNA nanomachine.

CHEMICAL SCIENCE (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Simple Single-Legged DNA Walkers at Diffusion-Limited Nanointerfaces of Gold Nanoparticles Driven by a DNA Circuit Mechanism

Motoi Oishi et al.

ACS NANO (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Dynamic Programming of a DNA Walker Controlled by Protons

Dongbao Yao et al.

ACS NANO (2020)

添加到收藏夹

Article Biophysics

A three-dimensional DNA nanomachine with target recycling amplification technology and multiple electrochemiluminescence resonance energy transfer for sensitive microRNA-141 detection

Cun Wang et al.

BIOSENSORS & BIOELECTRONICS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Regeneration of Burnt Bridges on a DNA Catenane Walker

Julian Valero et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Article Chemistry, Analytical

Efficient and Reliable MicroRNA Imaging in Living Cells via a FRET-Based Localized Hairpin-DNA Cascade Amplifier

Lu Liu et al.

ANALYTICAL CHEMISTRY (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

In Situ Amplification-Based Imaging of RNA in Living Cells

Zhihe Qing et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Article Biophysics

Two-layer three-dimensional DNA walker with highly integrated entropy-driven and enzyme-powered reactions for HIV detection

Changjing Yuan et al.

BIOSENSORS & BIOELECTRONICS (2019)

添加到收藏夹

Article Chemistry, Analytical

Telomerase Triggered DNA Walker with a Superhairpin Structure for Human Telomerase Activity Sensing

Jing Huang et al.

ANALYTICAL CHEMISTRY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Probing and Controlling Dynamic Interactions 27 at Biomolecule-Nanoparticle Interfaces Using Stochastic DNA Walkers

Sean D. Mason et al.

ACS NANO (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nicking-Assisted Reactant Recycle To Implement Entropy-Driven DNA Circuit

Cheng Zhang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Catalytic Self-Assembly of Quantum-Dot-Based MicroRNA Nanosensor Directed by Toehold-Mediated Strand Displacement Cascade

Fei Ma et al.

NANO LETTERS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Stochastic DNA Walkers in Droplets for Super-Multiplexed Bacterial Phenotype Detection

Mingshu Xiao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

An enzyme-free molecular catalytic device: dynamically self-assembled DNA dendrimers for in situ imaging of microRNAs in live cells

Shuzhen Yue et al.

CHEMICAL SCIENCE (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Bioapplications of DNA nanotechnology at the solid-liquid interface

Wenjing Wang et al.

CHEMICAL SOCIETY REVIEWS (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

Suping Li et al.

NATURE BIOTECHNOLOGY (2018)

添加到收藏夹

Article Nanoscience & Nanotechnology

A bio-hybrid DNA rotor-stator nanoengine that moves along predefined tracks

Julian Valero et al.

NATURE NANOTECHNOLOGY (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

A highly integrated DNA nanomachine operating in living cells powered by an endogenous stimulus

Pei-Qiang Ma et al.

CHEMICAL SCIENCE (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Simulation-guided engineering of an enzyme-powered three dimensional DNA nanomachine for discriminating single nucleotide variants

Yongya Li et al.

CHEMICAL SCIENCE (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Lighting Up MicroRNA in Living Cells by the Disassembly of Lock-Like DNA-Programmed UCNPs-AuNPs through the Target Cycling Amplification Strategy

Keying Zhang et al.

SMALL (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

DNA-Au Nanomachine Equipped with i-Motif and G-Quadruplex for Triple Combinatorial Anti-Tumor Therapy

Hyeongmok Park et al.

ADVANCED FUNCTIONAL MATERIALS (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Evaluation of intracellular telomerase activity through cascade DNA logic gates

Wenjing Wang et al.

CHEMICAL SCIENCE (2017)

添加到收藏夹

Article Multidisciplinary Sciences

A microRNA-initiated DNAzyme motor operating in living cells

Hanyong Peng et al.

NATURE COMMUNICATIONS (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Fabricating MnO2 Nanozymes as Intracellular Catalytic DNA Circuit Generators for Versatile Imaging of Base-Excision Repair in Living Cells

Feng Chen et al.

ADVANCED FUNCTIONAL MATERIALS (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Rational Engineering of a Dynamic, Entropy-Driven DNA Nanomachine for Intracellular MicroRNA Imaging

Cheng-Pin Liang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Near-Infrared Photothermally Activated DNAzyme-Gold Nanoshells for Imaging Metal Ions in Living Cells

Wenjing Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Article Chemistry, Analytical

Reliable Forster Resonance Energy Transfer Probe Based on Structure-Switching DNA for Ratiometric Sensing of Telomerase in Living Cells

Xue-Jiao Yang et al.

ANALYTICAL CHEMISTRY (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

An Exonuclease III-Powered, On-Particle Stochastic DNA Walker

Xiangmeng Qu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Catalytic Molecular Imaging of MicroRNA in Living Cells by DNA-Programmed Nanoparticle Disassembly

Xuewen He et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

添加到收藏夹

Article Nanoscience & Nanotechnology

A stochastic DNA walker that traverses a microparticle surface

C. Jung et al.

NATURE NANOTECHNOLOGY (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enzyme-Powered Three-Dimensional DNA Nanomachine for DNA Walking, Payload Release, and Biosensing

Xiaolong Yang et al.

ACS NANO (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Scissor-Like Chiral Metamolecules for Probing Intracellular Telomerase Activity

Maozhong Sun et al.

ADVANCED FUNCTIONAL MATERIALS (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Multigaps Embedded Nanoassemblies Enhance In Situ Raman Spectroscopy for Intracellular Telomerase Activity Sensing

Liguang Xu et al.

ADVANCED FUNCTIONAL MATERIALS (2016)

添加到收藏夹

Review Chemistry, Multidisciplinary

Isothermal Amplification of Nucleic Acids

Yongxi Zhao et al.

CHEMICAL REVIEWS (2015)

添加到收藏夹

Article Multidisciplinary Sciences

A Controllable Aptamer-Based Self-Assembled DNA Dendrimer for High Affinity Targeting, Bioimaging and Drug Delivery

Huimin Zhang et al.

SCIENTIFIC REPORTS (2015)

添加到收藏夹

Review Chemistry, Multidisciplinary

Sensing through signal amplification

Paolo Scrimin et al.

CHEMICAL SOCIETY REVIEWS (2011)

添加到收藏夹

Review Chemistry, Multidisciplinary

Emerging nanomaterials for targeting subcellular organelles

Jasper G. Huang et al.

NANO TODAY (2011)

添加到收藏夹

Review Nanoscience & Nanotechnology

Challenges and opportunities for structural DNA nanotechnology

Andre V. Pinheiro et al.

NATURE NANOTECHNOLOGY (2011)

添加到收藏夹

Review Chemistry, Multidisciplinary

Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials

Feng Zhao et al.

SMALL (2011)

添加到收藏夹

Article Chemistry, Multidisciplinary

Artificial DNA Nano-Spring Powered by Protons

Chunyan Wang et al.

ADVANCED MATERIALS (2010)

添加到收藏夹

Article Multidisciplinary Sciences

Engineering entropy-driven reactions and networks catalyzed by DNA

David Yu Zhang et al.

SCIENCE (2007)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Protein biomarker discovery and validation: the long and uncertain path to clinical utility

Nader Rifai et al.

NATURE BIOTECHNOLOGY (2006)

添加到收藏夹

Review Chemistry, Multidisciplinary

Rational design of DNA nanoarchitectures

U Feldkamp et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)

添加到收藏夹

Article Chemistry, Analytical

Microfluidic biosensor for the serotype-specific detection of Dengue virus RNA

NV Zaytseva et al.

ANALYTICAL CHEMISTRY (2005)

添加到收藏夹

Review Oncology

Biomarkers in cancer staging, prognosis and treatment selection

JA Ludwig et al.

NATURE REVIEWS CANCER (2005)

添加到收藏夹

Review Oncology

Proteomic applications for the early detection of cancer

JD Wulfkuhle et al.

NATURE REVIEWS CANCER (2003)

添加到收藏夹

Article Physics, Fluids & Plasmas

Using DNA to construct and power a nanoactuator

FC Simmel et al.

PHYSICAL REVIEW E (2001)

添加到收藏夹

Article Chemistry, Multidisciplinary

A highly sensitive and selective catalytic DNA biosensor for lead ions

J Li et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)

添加到收藏夹

Article Multidisciplinary Sciences

A DNA-fuelled molecular machine made of DNA

B Yurke et al.

NATURE (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.