Trends in hospitalization for urinary tract infection in the paediatric age group in the 2000-2015 period in Spain

Objective: To analyse the trends in hospital admissions related to urinary tract infection among children aged 0-14 years in Spain in the 2000--2015 period. Methods: We conducted a retrospective observational study using the minimum basic hospital discharge dataset system of Spain, which applies the International Classification of Diseases, version 9 (ICD-9) coding system. We included every hospitalization due to cystitis, pyelonephritis and unspecified UTI among children aged less than 15 years. We collected data on patient sex and age, type of discharge, main diagnosis, comorbidities, length of stay and overall cost. We calculated crude hospitalization rates per 1000 inhabitants aged less than 15 years and performed a joinpoint regression analysis to identify temporal trends. Results: In the 2000-2015 period, there were 124 696 hospitalizations in children under 15 years. Of these patients, 72.97% were aged 0--1 year and 60.12% had a diagnosis of unspecified UTI, 39.27% of pyelonephritis, and 0.52% of cystitis. The crude rate of hospitalization due to UTI ranged from 1.24 in year 2000 to 0.98 in 2015. The rate of hospitalization was higher in female versus male patients. The joinpoint analysis found a decreasing trend in the rate of hospitalization due to UTI, with an average annual percent change (AAPC) of -1.5% (95% confidence interval [CI], -2.4 to -0.6). The largest decreases occurred in female patients (AAPC, -1.8; 95% CI, -2.5 to -1.0) and children aged 7--10 years (AAPC -5.9; 95% CI, -6.7 to - 5.2). Conclusions: The rate of hospitalization related to UTI in Spain in patients aged up to 14 years decreased during the 2000-2015 period. The highest hospitalization rates occurred in female patients and in the 0-to-1 year age group.(c) 2022 Asociacion Espan tilde ola de Pediatri acute accent a. Published by Elsevier Espan tilde a, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/ 4.0/).

Automated summary

This study analyzed the trends in hospital admissions related to urinary tract infection among children aged 0-14 years in Spain from 2000 to 2015, and found a decrease in hospitalization rates. The highest hospitalization rates were observed in female patients and the 0-1 year age group.