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Case Report: Amphotericin B and Mefloquine as a Salvage Treatment of Alveolar Echinococcosis

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AMER SOC TROP MED & HYGIENE
DOI: 10.4269/ajtmh.22-0465

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A patient with advanced alveolar echinococcosis was effectively treated with a combination regimen of amphotericin B deoxycholate and mefloquine as a rescue therapy due to albendazole intolerance.
Alveolar echinococcosis is an emerging zoonotic disease caused by the parasite Echinococcus multilocu-laris. Most patients are diagnosed at a late stage, when lifelong treatment with benzimidazoles is required to stop disease progression. However, for patients who do not tolerate benzimidazole therapy, there are no alternatives. Here, we present a patient with advanced alveolar echinococcosis who was successfully treated with amphotericin B deoxycholate and mefloquine as a rescue therapy after he developed albendazole intolerance.

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