4.7 Review

Recent Developments in Enantioselective Domino Reactions. Part B: First Row Metal Catalysts

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ADVANCED SYNTHESIS & CATALYSIS
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WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.202300002

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domino reactions; multicomponent reactions; transition metals; first row metals; asymmetric synthesis

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This review updates the research in the field of enantioselective domino reactions promoted by chiral catalysts derived from first row metals, such as zinc, iron, copper, scandium, nickel, cobalt, titanium, chromium and magnesium, since the beginning of 2019. It illustrates the impressive range of novel highly enantioselective domino reactions that can be achieved with a diversity of these catalysts, providing a one-pot access to very complex and functionalized chiral molecules from simple starting materials.
This review updates the field of enantioselective domino reactions promoted by chiral catalysts derived from first row metals, such as zinc, iron, copper, scandium, nickel, cobalt, titanium, chromium and magnesium as special case, published since the beginning of 2019. It illustrates how much a diversity of these catalysts allow an impressive range of novel highly enantioselective domino reactions of many types to be achieved, providing a one-pot access to very complex and functionalized chiral molecules from simple starting materials.

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