4.7 Review

Recent Developments in Enantioselective Domino Reactions. Part A: Noble Metal Catalysts

期刊

ADVANCED SYNTHESIS & CATALYSIS
卷 365, 期 5, 页码 620-681

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.202201284

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domino reactions; multicomponent reactions; transition metals; noble metals; asymmetric synthesis

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This review provides an update on the field of enantioselective domino reactions catalyzed by chiral catalysts derived from noble metals, such as palladium, silver, rhodium, ruthenium, iridium, and gold, since the beginning of 2019. It showcases the diverse range of these catalysts, enabling unprecedented asymmetric domino reactions with excellent enantioselectivity and providing access to a wide variety of complex chiral molecules.
This review updates the field of enantioselective domino reactions promoted by chiral catalysts derived from noble metals, including palladium, silver, rhodium, ruthenium, iridium and gold, published since the beginning of 2019. It illustrates how much a diversity of these catalysts allow unprecedented asymmetric domino reactions of many types to be achieved with excellent enantioselectivity, giving a direct access to a wide variety of complex chiral molecules.

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