4.5 Review

Walking the tightrope: proteostasis and neurodegenerative disease

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

The Biology of Proteostasis in Aging and Disease

Johnathan Labbadia et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)

Review Pharmacology & Pharmacy

Targeting Hsp90/Hsp70-Based Protein Quality Control for Treatment of Adult Onset Neurodegenerative Diseases

William B. Pratt et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 55 (2015)

Article Biochemistry & Molecular Biology

Widespread Proteome Remodeling and Aggregation in Aging C-elegans

Dirk M. Walther et al.

Article Biochemistry & Molecular Biology

Neuronal Serotonin Release Triggers the Heat Shock Response in C. elegans in the Absence of Temperature Increase

Marcus C. Tatum et al.

CURRENT BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Compartment-specific aggregases direct distinct nuclear and cytoplasmic aggregate deposition

Stephanie B. M. Miller et al.

EMBO JOURNAL (2015)

Review Biochemistry & Molecular Biology

The Chemical Biology of Molecular Chaperones-Implications for Modulation of Proteostasis

Kristoffer R. Brandvold et al.

JOURNAL OF MOLECULAR BIOLOGY (2015)

Review Biochemistry & Molecular Biology

Spatially Organized Aggregation of Misfolded Proteins as Cellular Stress Defense Strategy

Stephanie B. M. Miller et al.

JOURNAL OF MOLECULAR BIOLOGY (2015)

Article Neurosciences

Cell type- and brain region-resolved mouse brain proteome

Kirti Sharma et al.

NATURE NEUROSCIENCE (2015)

Article Multidisciplinary Sciences

Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control

Irene Gallina et al.

NATURE COMMUNICATIONS (2015)

Article Multidisciplinary Sciences

Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions

Natalie E. Farrawell et al.

SCIENTIFIC REPORTS (2015)

Review Biochemistry & Molecular Biology

Small heat-shock proteins: important players in regulating cellular proteostasis

Teresa M. Treweek et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2015)

Review Clinical Neurology

Promoting Autophagic Clearance: Viable Therapeutic Targets in Alzheimer's Disease

Lauren G. Friedman et al.

NEUROTHERAPEUTICS (2015)

Review Biochemistry & Molecular Biology

Multi-layered molecular mechanisms of polypeptide holding, unfolding and disaggregation by HSP70/HSP110 chaperones

Andrija Finka et al.

FRONTIERS IN MOLECULAR BIOSCIENCES (2015)

Review Biochemistry & Molecular Biology

Preventing α-synuclein aggregation: The role of the small heat-shock molecular chaperone proteins

Dezerae Cox et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)

Article Mathematical & Computational Biology

A systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy

Laura Caberlotto et al.

BMC SYSTEMS BIOLOGY (2014)

Review Pharmacology & Pharmacy

Mitochondrial protein quality control in health and disease

Michael J. Baker et al.

BRITISH JOURNAL OF PHARMACOLOGY (2014)

Article Biochemistry & Molecular Biology

TRPV1 Pain Receptors Regulate Longevity and Metabolism by Neuropeptide Signaling

Celine E. Riera et al.

Article Biochemistry & Molecular Biology

Misfolded Polyglutamine, Polyalanine, and Superoxide Dismutase 1 Aggregate via Distinct Pathways in the Cell

Saskia Polling et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Medicine, Research & Experimental

The deubiquitinase U5P28 controls intestinal homeostasis and promotes colorectal cancer

Markus E. Diefenbacher et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Biochemistry & Molecular Biology

Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis

Julie D. Atkin et al.

JOURNAL OF NEUROCHEMISTRY (2014)

Article Clinical Neurology

Frontotemporal dementia and its subtypes: a genome-wide association study

Raffaele Ferrari et al.

LANCET NEUROLOGY (2014)

Article Multidisciplinary Sciences

A three-dimensional human neural cell culture model of Alzheimer's disease

Se Hoon Choi et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

Sami J. Barmada et al.

NATURE CHEMICAL BIOLOGY (2014)

Review Cell Biology

The amyloid state and its association with protein misfolding diseases

Tuomas P. J. Knowles et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Review Pharmacology & Pharmacy

The role of heat shock proteins in Amyotrophic Lateral Sclerosis: The therapeutic potential of Arimoclomol

Bernadett Kalmar et al.

PHARMACOLOGY & THERAPEUTICS (2014)

Article Multidisciplinary Sciences

Hypochlorite-induced structural modifications enhance the chaperone activity of human α2-macroglobulin

Amy R. Wyatt et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition

Anan Yu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms

Leslie I. Grad et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

HSF-1-mediated cytoskeletal integrity determines thermotolerance and life span

Nathan A. Baird et al.

SCIENCE (2014)

Article Multidisciplinary Sciences

PICALM modulates autophagy activity and tau accumulation

Kevin Moreau et al.

NATURE COMMUNICATIONS (2014)

Article Multidisciplinary Sciences

From cartoon to real time MRI: in vivo monitoring of phagocyte migration in mouse brain

Yuki Mori et al.

SCIENTIFIC REPORTS (2014)

Review Biochemistry & Molecular Biology

Extracellular Chaperones and Proteostasis

Amy R. Wyatt et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82 (2013)

Review Biochemistry & Molecular Biology

Molecular Chaperone Functions in Protein Folding and Proteostasis

Yujin E. Kim et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82 (2013)

Article Biochemistry & Molecular Biology

XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity

Rebecca C. Taylor et al.

Article Biochemistry & Molecular Biology

Neuronal Ubiquitin Homeostasis

Jada Hallengren et al.

CELL BIOCHEMISTRY AND BIOPHYSICS (2013)

Review Biochemistry & Molecular Biology

The pathways of mitophagy for quality control and clearance of mitochondria

G. Ashrafi et al.

CELL DEATH AND DIFFERENTIATION (2013)

Article Biochemistry & Molecular Biology

The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function

Owen A. Brady et al.

HUMAN MOLECULAR GENETICS (2013)

Article Biochemistry & Molecular Biology

A Platform to View Huntingtin Exon 1 Aggregation Flux in the Cell Reveals Divergent Influences from Chaperones hsp40 and hsp70

Angelique R. Ormsby et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Clinical Neurology

Induced pluripotent stem cells as tools for disease modelling and drug discovery in Alzheimer's disease

Lezanne Ooi et al.

JOURNAL OF NEURAL TRANSMISSION (2013)

Article Biochemistry & Molecular Biology

Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration

Andrey S. Tsvetkov et al.

NATURE CHEMICAL BIOLOGY (2013)

Editorial Material Cell Biology

Autophagic cell death exists

Peter G. H. Clarke et al.

AUTOPHAGY (2012)

Article Biochemistry & Molecular Biology

Transitory phases of autophagic death and programmed necrosis during superoxide-induced neuronal cell death

Gavin C. Higgins et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Article Biotechnology & Applied Microbiology

Effect of αB-Crystallin on Protein Aggregation in Drosophila

Nguyen Trong Tue et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2012)

Article Multidisciplinary Sciences

Compartmentalization of superoxide dismutase 1 (SOD1G93A) aggregates determines their toxicity

Sarah J. Weisberg et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Cardiac & Cardiovascular Systems

Heat Shock Protein-Inducing Compounds as Therapeutics to Restore Proteostasis in Atrial Fibrillation

Femke Hoogstra-Berends et al.

TRENDS IN CARDIOVASCULAR MEDICINE (2012)

Review Biochemistry & Molecular Biology

Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

Julius Anckar et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 80 (2011)

Review Neurosciences

Neuronal Intrinsic Mechanisms of Axon Regeneration

Kai Liu et al.

ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 (2011)

Review Biochemistry & Molecular Biology

Ubiquitin-Proteasome System and mitochondria - Reciprocity

Nurit Livnat-Levanon et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2011)

Article Biochemistry & Molecular Biology

Autophagic activity in cortical neurons under acute oxidative stress directly contributes to cell death

Gavin C. Higgins et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2011)

Article Biochemistry & Molecular Biology

Clusterin facilitates in vivo clearance of extracellular misfolded proteins

Amy R. Wyatt et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2011)

Article Biochemistry & Molecular Biology

Ubiquitin-dependent mitochondrial protein degradation

Jin-Mi Heo et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)

Article Environmental Sciences

GENERALIZATION OF THE PRION HYPOTHESIS TO OTHER NEURODEGENERATIVE DISEASES: AN IMPERFECT FIT

Will C. Guest et al.

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2011)

Review Multidisciplinary Sciences

Molecular chaperones in protein folding and proteostasis

F. Ulrich Hartl et al.

NATURE (2011)

Review Biochemistry & Molecular Biology

Chemical modulators of autophagy as biological probes and potential therapeutics

Angeleen Fleming et al.

NATURE CHEMICAL BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Identifying polyglutamine protein species in situ that best predict neurodegeneration

Jason Miller et al.

NATURE CHEMICAL BIOLOGY (2011)

Review Neurosciences

The role of ubiquitylation in nerve cell development

Hiroshi Kawabe et al.

NATURE REVIEWS NEUROSCIENCE (2011)

Article Multidisciplinary Sciences

Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells

Navin R. Mahadevan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Biochemistry & Molecular Biology

Exploring the link between glucocerebrosidase mutations and parkinsonism

Wendy Westbroek et al.

TRENDS IN MOLECULAR MEDICINE (2011)

Review Cell Biology

Ubiquitination in Postsynaptic Function and Plasticity

Angela M. Mabb et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 26 (2010)

Article Clinical Neurology

TDP-43 Redistribution is an Early Event in Sporadic Amyotrophic Lateral Sclerosis

Maria Teresa Giordana et al.

BRAIN PATHOLOGY (2010)

Article Neurosciences

Protein Aggregation and Defective RNA Metabolism as Mechanisms for Motor Neuron Damage

N. Ticozzi et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2010)

Review Neurosciences

Oxidative Stress: Emerging Mitochondrial and Cellular Themes and Variations in Neuronal Injury

Gavin C. Higgins et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Review Cell Biology

Heat shock factors: integrators of cell stress, development and lifespan

Malin Akerfelt et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Review Neurosciences

Chaperone networks: Tipping the balance in protein folding diseases

Cindy Voisine et al.

NEUROBIOLOGY OF DISEASE (2010)

Review Physiology

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

Brinda Ravikumar et al.

PHYSIOLOGICAL REVIEWS (2010)

Article Multidisciplinary Sciences

The HSP70 Molecular Chaperone Is Not Beneficial in a Mouse Model of α-synucleinopathy

Derya R. Shimshek et al.

PLOS ONE (2010)

Article Biochemistry & Molecular Biology

Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans

Della C. David et al.

PLOS BIOLOGY (2010)

Article Biochemistry & Molecular Biology

An Inhibitor of a Deubiquitinating Enzyme Regulates Ubiquitin Homeostasis

Yoko Kimura et al.

Article Biochemistry & Molecular Biology

α2-Macroglobulin and Haptoglobin Suppress Amyloid Formation by Interacting with Prefibrillar Protein Species

Justin J. Yerbury et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

The Molecular Chaperone Hsp90 Modulates Intermediate Steps of Amyloid Assembly of the Parkinson-related Protein α-Synuclein

S. Fabio Falsone et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Multidisciplinary Sciences

Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS

Jiou Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

Anat Ben-Zvi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

An Analytical Solution to the Kinetics of Breakable Filament Assembly

Tuomas P. J. Knowles et al.

SCIENCE (2009)

Article Biochemistry & Molecular Biology

Protease activation of α2-Macroglobulin modulates a chaperone-like action with broad specificity

Katie French et al.

BIOCHEMISTRY (2008)

Article Multidisciplinary Sciences

Misfolded proteins partition between two distinct quality control compartments

Daniel Kaganovich et al.

NATURE (2008)

Review Multidisciplinary Sciences

Adapting proteostasis for disease intervention

William E. Balch et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

The mouse polyubiquitin gene Ubb is essential for meiotic progression

Kwon-Yul Ryu et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Article Clinical Neurology

Proteomic identification of novel proteins in cortical Lewy bodies

James B. Leverenz et al.

BRAIN PATHOLOGY (2007)

Article Multidisciplinary Sciences

Proteasome Activator Enhances Survival of Huntington's Disease Neuronal Model Cells

Hyemyung Seo et al.

PLOS ONE (2007)

Article Biochemistry & Molecular Biology

Alteration of familial ALS-linked mutant SOD1 solubility with disease progression: Its modulation by the proteasome and Hsp70

S Koyama et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Cell Biology

A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling

NP Dantuma et al.

JOURNAL OF CELL BIOLOGY (2006)

Article Multidisciplinary Sciences

Progressive disruption of cellular protein folding in models of polyglutamine diseases

T Gidalevitz et al.

SCIENCE (2006)

Article Neurosciences

Delayed development of adult-generated granule cells in dentate gyrus

LS Overstreet-Wadiche et al.

JOURNAL OF NEUROSCIENCE (2006)

Article Cell Biology

Ubiquitin crosstalk connecting cellular processes

Tom A. M. Groothuis et al.

CELL DIVISION (2006)

Article Biochemistry & Molecular Biology

Loss of Usp14 results in reduced levels of ubiquitin in ataxia mice

C Anderson et al.

JOURNAL OF NEUROCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models

M Fujimoto et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Cell Biology

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

M Komatsu et al.

JOURNAL OF CELL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Heat shock protein 70 inhibits α-synuclein fibril formation via preferential binding to prefibrillar species

MM Dedmon et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Cell Biology

Autophagy and its possible roles in nervous system diseases, damage and repair

David C. Rubinszfein et al.

AUTOPHAGY (2005)

Review Cell Biology

Proteolysis: from the lysosome to ubiquitin and the proteasome

A Ciechanover

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Ubiquitin depletion as a key mediator of toxicity by translational inhibitors

J Hanna et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron

H Osaka et al.

HUMAN MOLECULAR GENETICS (2003)

Article Biochemistry & Molecular Biology

TorsinA and heat shock proteins act as molecular chaperones:: suppression of α-synuclein aggregation

PJ McLean et al.

JOURNAL OF NEUROCHEMISTRY (2002)

Article Multidisciplinary Sciences

Dynamic changes in the localization of thermally unfolded nuclear proteins chaperone-dependent associated with protection

EAA Nollen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Cell Biology

A novel quality control compartment derived from the endoplasmic reticulum

S Kamhi-Nesher et al.

MOLECULAR BIOLOGY OF THE CELL (2001)

Review Cell Biology

Aggresomes, inclusion bodies and protein aggregation

RR Kopito

TRENDS IN CELL BIOLOGY (2000)

Article Multidisciplinary Sciences

Ubiquitin is part of the retrovirus budding machinery

A Patnaik et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Biochemistry & Molecular Biology

p53 accumulation due to down-regulation of ubiquitin: relevance for neuronal apoptosis

Z Tan et al.

CELL DEATH AND DIFFERENTIATION (2000)