相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Design and outcome measures of LAVENDER, a phase 3 study of trofinetide for Rett syndrome
Jeffrey L. Neul et al.
CONTEMPORARY CLINICAL TRIALS (2022)
Glycyl-L-Prolyl-L-Glutamate Pseudotripeptides for Treatment of Alzheimer's Disease
Hasan Turkez et al.
BIOMOLECULES (2021)
Design, Synthesis, and Biological Evaluation of Hybrid Glypromate Analogues Using 2-Azanorbornane as a Prolyl and Pipecolyl Surrogate
Ivo E. Sampaio-Dias et al.
ACS CHEMICAL NEUROSCIENCE (2021)
Macrocyclization strategies for cyclic peptides and peptidomimetics
Clement Bechtler et al.
RSC MEDICINAL CHEMISTRY (2021)
Effects of a Tripeptide on Mitogen-Activated Protein Kinase and Glycogen Synthase Kinase Activation in a Cell Line Derived from the Foetal Hippocampus of a Trisomy 16 Mouse: an Animal Model of Down Syndrome
Tushar Arora et al.
NEUROTOXICITY RESEARCH (2020)
A Double-Blind, Randomized, Placebo-Controlled Clinical Study of Trofinetide in the Treatment of Fragile X Syndrome
Elizabeth Berry-Kravis et al.
PEDIATRIC NEUROLOGY (2020)
Bioinspired design for the assembly of Glypromate® neuropeptide conjugates with active pharmaceutical ingredients
Sara C. Silva-Reis et al.
NEW JOURNAL OF CHEMISTRY (2020)
A sustainable strategy for the assembly of Glypromate® and its structurally-related analogues by tandem sequential peptide coupling
Ivo E. Sampaio-Dias et al.
GREEN CHEMISTRY (2020)
Double-blind, randomized, placebo-controlled study of trofinetide in pediatric Rett syndrome
Daniel G. Glaze et al.
NEUROLOGY (2019)
Synthesis and biological evaluation of novel analogues of Gly-L-Pro-L-Glu (GPE) as neuroprotective agents
Lisa Marinelli et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)
(±)-3,5-Bis(substitutedmethyl)pyrrolidines: Application to the Synthesis of Analogues of Glycine-L-proline-L-glutamic Acid (GPE)
Joana Ferreira da Costa et al.
CURRENT ORGANIC SYNTHESIS (2018)
GPE Promotes the Proliferation and Migration of Mouse Embryonic Neural Stem Cells and Their Progeny In Vitro
Cristina Almenglo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
(R)-α-Lipoyl-Gly-L-Pro-L-Glu dimethyl ester as dual acting agent for the treatment of Alzheimer's disease
Lisa Marinelli et al.
NEUROPEPTIDES (2017)
Highly efficient one-pot assembly of peptides by double chemoselective coupling
Ivo E. Sampaio-Dias et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2017)
A Double-Blind, Randomized, Placebo-Controlled Clinical Study of Trofinetide in the Treatment of Rett Syndrome
Daniel G. Glaze et al.
PEDIATRIC NEUROLOGY (2017)
Graphene quantum dots conjugated neuroprotective peptide improve learning and memory capability
Songhua Xiao et al.
BIOMATERIALS (2016)
Development of glycine-α-methyl-proline-containing tripeptides with neuroprotective properties
Ivana Cacciatore et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Incorporation of Trifluoromethylated Proline and Surrogates into Peptides: Application to the Synthesis of Fluorinated Analogues of the Neuroprotective Glycine-Proline-Glutamate (GPE) Tripeptide
Julien Simon et al.
JOURNAL OF ORGANIC CHEMISTRY (2016)
The role for IGF-1-derived small neuropeptides as a therapeutic target for neurological disorders
Jian Guan et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2015)
Fluorescent graphene quantum dots as traceable, pH-sensitive drug delivery systems
Jichuan Qiu et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2015)
Macrocycles: lessons from the distant past, recent developments, and future directions
Andrei K. Yudin
CHEMICAL SCIENCE (2015)
The IGF-derived tripeptide Gly-Pro-Glu is a weak NMDA receptor agonist
Christopher E. Vaaga et al.
JOURNAL OF NEUROPHYSIOLOGY (2014)
An Efficient Fmoc Solid-Phase Synthesis of an Amphiphile of the Neuroprotective Agent Glycyl-prolyl-glutamic Acid
Paul W. R. Harris et al.
SYNLETT (2014)
In Vivo Biodistribution and Toxicology of Carboxylated Graphene Quantum Dots
Md Nurunnabi et al.
ACS NANO (2013)
Synthesis and Self-Assembly of a Peptide-Amphiphile as a Drug Delivery Vehicle
Soo Jung Son et al.
AUSTRALIAN JOURNAL OF CHEMISTRY (2013)
Impact of fluorination on proteolytic stability of peptides in human blood plasma
Vivian Asante et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Synthesis and allosteric modulation of the dopamine receptor by peptide analogs of L-prolyl-L-leucyl-glycinamide (PLG) modified in the L-proline or L-proline and L-leucine scaffolds
Joana Ferreira da Costa et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Mechanism of Action for NNZ-2566 Anti-inflammatory Effects Following PBBI Involves Upregulation of Immunomodulator ATF3
Casandra M. Cartagena et al.
NEUROMOLECULAR MEDICINE (2013)
Molecular mechanism underlying the cerebral effect of Gly-Pro-Glu tripeptide bound to L-dopa in a Parkinson's animal model
Alba Minelli et al.
AMINO ACIDS (2012)
(R)-α-Lipoyl-Glycyl-L-Prolyl-L-Glutamyl Dimethyl Ester Codrug as a Multifunctional Agent with Potential Neuroprotective Activities
Ivana Cacciatore et al.
CHEMMEDCHEM (2012)
GPE and GPE Analogues as Promising Neuroprotective Agents
I. Cacciatore et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2012)
Insulin-like growth factor 1 (IGF1) and its active peptide (1-3)IGF1 enhance the expression of synaptic markers in neuronal circuits through different cellular mechanisms
Aiden P. Corvin et al.
NEUROSCIENCE LETTERS (2012)
First peptide/protein PEGylation with functional polymers designed by nitroxide-mediated polymerization
Marion Chenal et al.
POLYMER CHEMISTRY (2011)
Graphene and Graphene Oxide: Synthesis, Properties, and Applications
Yanwu Zhu et al.
ADVANCED MATERIALS (2010)
Green Chemistry: Principles and Practice
Paul Anastas et al.
CHEMICAL SOCIETY REVIEWS (2010)
Synthesis of methyl (±)-3,5-bis(substitutedmethyl)pyrrolidine-2-carboxylates: a convenient approach to proline-mimetics
Joana Ferreira da Costa et al.
TETRAHEDRON (2010)
IGF-1 derived small neuropeptides and analogues: a novel strategy for the development of pharmaceuticals for neurological conditions
Jian Guan et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
NNZ-2566, a glypromate analog, attenuates brain ischemia-induced non-convulsive seizures in rats
Xi-Chun M. Lu et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2009)
The N-terminal tripeptide of insulin-like growth factor-I protects against β-amyloid-induced somatostatin depletion by calcium and glycogen synthase kinase 3β modulation
Emma Burgos-Ramos et al.
JOURNAL OF NEUROCHEMISTRY (2009)
NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats
Hans H. Wei et al.
JOURNAL OF NEUROINFLAMMATION (2009)
NNZ-2566, a Glypromate Analog, Improves Functional Recovery and Attenuates Apoptosis and Inflammation in a Rat Model of Penetrating Ballistic-Type Brain Injury
Xi-Chun May Lu et al.
JOURNAL OF NEUROTRAUMA (2009)
NNZ-2566: A Gly-Pro-Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke
Michael J. Bickerdike et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2009)
Delayed peripheral administration of the N-terminal tripeptide of IGF-1 (GPE) reduces brain damage following microsphere induced embolic damage in young adult and aged rats
Shlomo Shapira et al.
NEUROSCIENCE LETTERS (2009)
Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice
Daniela Tropea et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Use of 'Click Chemistry' for the Synthesis of Tetrazole-Containing Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid
Ku-yuan Hung et al.
SYNLETT (2009)
Nano-Graphene Oxide for Cellular Imaging and Drug Delivery
Xiaoming Sun et al.
NANO RESEARCH (2008)
Delayed peripheral administration of a GPE analogue induces astrogliosis and angiogenesis and reduces inflammation and brain injury following hypoxia-ischemia in the neonatal rat
Pernilla Svedin et al.
DEVELOPMENTAL NEUROSCIENCE (2007)
Lipoic acid as a novel treatment for Alzheimer's disease and related dementias
Lina Holmquist et al.
PHARMACOLOGY & THERAPEUTICS (2007)
The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity
Sergio A. Alonso De Diego et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
New Gly-Pro-Glu (GPE) analogues:: Expedite solid-phase synthesis and biological activity
SAA De Diego et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Synthesis of macrocyclic analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE)
Paul W. R. Harris et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2006)
Synthesis of proline-modified analogues of the neuroprotective agent glycyl-L-prolyl-glutamic acid (GPE)
PWR Harris et al.
TETRAHEDRON (2005)
Analogues of the neuroprotective tripeptide Gly-Pro-Glu (GPE):: synthesis and structure-activity relationships
SAA De Diego et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Central penetration and stability of N-terminal tripeptide of insulin-like growth factor-I, glycine-proline-glutamate in adult rat
AM Baker et al.
NEUROPEPTIDES (2005)
Synthesis and pharmacological evaluation of side chain modified glutamic acid analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE)
MA Brimble et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
Synthesis and pharmacological evaluation of glycine-modified analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE)
MYH Lai et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
Synthesis and neuroprotective activity of analogues of glycyl-L-prolyl-L-glutamic acid (GPE) modified at the α-carboxylic acid
NS Trotter et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
Combining insulin-like growth factor derivatives plus caffeinol produces robust neuroprotection after stroke in rats
XR Zhao et al.
STROKE (2005)
Gly-Pro-Glu protects β-amyloid-induced somatostatin depletion in the rat cortex
D Aguado-Liera et al.
NEUROREPORT (2004)
N-terminal tripeptide of IGF-I improves functional deficits after 6-OHDA lesion in rats
R Krishnamurthi et al.
NEUROREPORT (2004)
Neuroprotective effects of the N-terminal tripeptide of insulin-like growth factor-1, glycine-proline-glutamate (GPE) following intravenous infusion in hypoxic-ischemic adult rats
J Guan et al.
NEUROPHARMACOLOGY (2004)
Pharmacokinetics of glycine-proline-glutamate, the N-terminal tripeptide of insulin-like growth factor-1, in rats
DC Batchelor et al.
ANALYTICAL BIOCHEMISTRY (2003)
A three amino acid peptide, Gly-Pro-Arg, protects and rescues cell death induced by amyloid β-peptide
M Ioudina et al.
EXPERIMENTAL NEUROLOGY (2003)
Insulin-like growth factor-1 and post-ischemic brain injury
J Guan et al.
PROGRESS IN NEUROBIOLOGY (2003)
Synthesis of cyclic proline-containing peptides via ring-closing metathesis
PWR Harris et al.
ORGANIC LETTERS (2003)
From acquisition to consolidation: On the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning
WJ Tyler et al.
LEARNING & MEMORY (2002)
Structural basis for understanding structure-activity relationships for the glutamate binding site of the NMDA receptor
IG Tikhonova et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Expression and activation of matrix metalloproteinase-2 and-9 in rat brain after transient focal cerebral ischemia
AM Planas et al.
NEUROBIOLOGY OF DISEASE (2001)
Ligands for glutamate receptors:: Design and therapeutic prospects
H Bräuner-Osborne et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
N-terminal tripeptide of IGF-1 (GPE) prevents the loss of TH positive neurons after 6-OHDA induced nigral lesion in rats
J Guan et al.
BRAIN RESEARCH (2000)
分享论文
