期刊
JOURNAL OF NATURAL PRODUCTS
卷 79, 期 9, 页码 2315-2323出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jnatprod.6b00452
关键词
-
资金
- National Science Council of Taiwan [MOST104-2113-M-110-006, 104-2811-M-110-026, 104-2320-B-110-001-MY2]
Chemical investigation of the red alga Laurencia tristicha led to the discovery of eight new halogenated chamigrane-type sesquiterpenoids (1-8) and one new bromocuparane-type sesquiterpene (9), along with nine known related metabolites (10-18). Their structures were elucidated on the basis of extensive spectroscopic analyses, and the absolute configurations of 1-8 were proposed by comparison to the biosynthetically related known compound 12. Cytotoxicity, antibacterial, and anti-inflammatory activities of these isolates were also investigated. The results showed that compound 11 exhibited good antibacterial activity against Serratia marcescens compared to the positive control ampicillin at a dosage of 100 mu g/disk. Compound 17 showed strong inhibition toward elastase release generation at 10 mu M.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据