期刊
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
卷 16, 期 8, 页码 8772-8778出版社
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2016.12358
关键词
Biosensors; Copper Oxide; Screen Printed Electrodes; Nonenzymatic Glucose Sensors
类别
资金
- Department of Science and Technology (DST) [DST/INSPIRE Fellowship/2011/[4]]
A highly sensitive glucose sensor was developed by controlled electrodeposition of copper nanoparticles on the working electrode of an indigenously fabricated screen printed electrode. Morphology and crystal structure of CuO modified printed electrode was analyzed through high resolution scanning electron microscope and X-ray diffraction technique. Linear sweep voltammetry and amperometry were used to study the electro-catalytic activity of sensor electrode. The modified electrode showed excellent catalytic activity towards glucose oxidation with a sensitivity of 3225 mu A mM(-1) cm(-2), linear range from 0.5 mu M to 15 mM, and a limit of detection of 0.06 mu M. The sensor exhibited a very high selectivity to glucose in presence of interfering species such as ascorbic acid, dopamine, acetaminophen, uric acid, creatinine, sodium chloride, urea and other sugars (fructose, maltose, lactose and galactose). Its potential for commercial application was established by determination of glucose concentration in blood samples. The results were compared with the commercially available sensor strips and found to be in good agreement.
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