期刊
BYULLETEN SIBIRSKOY MEDITSINY
卷 21, 期 3, 页码 132-139出版社
SIBERIAN STATE MEDICAL UNIV
DOI: 10.20538/1682-0363-2022-3-132-139
关键词
breast cancer; radionuclide diagnosis; alternative scaffold proteins; HER2/neu
资金
- Ministry of Science and Higher Education [075-15-2022-1103]
This review discusses the diagnostic methods and treatment requirements for HER2-positive breast cancer, and presents the latest trends in radionuclide diagnosis using alternative scaffold proteins and their applications in clinical practice.
HER2-positive breast cancer occurs in 15-20% of breast cancer patients and is associated primarily with a poor prognosis of the disease and the need for highly specific targeted therapy. Despite the clinical importance of determining HER2/neu, traditional diagnostic methods have their disadvantages and require the study of new additional research techniques. The information presented in this review makes it possible to consider current trends in the radionuclide diagnosis of HER2-positive breast cancer using the latest class of alternative scaffold proteins and to consider various aspects of their use in clinical practice.
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