Deep eutectic solvents (DESs) as eco-friendly and sustainable solvent/catalyst systems in organic transformations

The development of efficient and environmentally benign synthetic protocols has attracted increasing interest in modern organic syntheses in view of the growing concern over the environment. As part of this green concept, eutectic solvents (DESs) have emerged as an interesting type of ionic liquid and have shown their usefulness as environmentally benign sustainable alternative to the conventional organic solvents in synthetic chemistry to increase efficiency of organic transformations. The synthetic methodology with the use of DES as green solvent and inexpensive, biodegradable, recyclable catalyst and with its experimental simplicity and maximum synthetic efficiency will be attractive for academic and industrial research looking forward for simple catalytic organic transformations to synthesize drug like small molecules with structural diversity and molecular complexity. The present review focuses on the use of environmentally benign and inexpensive DES as solvent and catalyst in the field of organic chemistry. (C) 2015 Elsevier B.V. All rights reserved.