期刊
SCANDINAVIAN JOURNAL OF PAIN
卷 22, 期 4, 页码 670-672出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/sjpain-2022-0088
关键词
evoked pain; neuropathy; pain mechanism; quantitative sensory testing; stratification
资金
- DFG [SFB1158]
Quantitative sensory testing (QST) has been optimized for diagnosing small fiber neuropathy, but current sensory phenotypes cannot successfully stratify neuropathy patients with and without pain.
Quantitative sensory testing (QST) has been optimized to diagnose in particular small fiber neuropathy and has been successfully used for decades. Sensory phenotypes have been derived from the QST data in an attempt to stratify patients with chronic pain and to gain mechanistic insights. However, studies consistently show that there is no difference in sensory phenotypes between neuropathy patients with and without pain and no successful stratification has been shown using the current version of sensory phenotypes. Thus, after falsification of the initial hypothesis it is time to focus on more promising approaches.
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