☆ 4.5 Article

Amphiphilic Chitosan Porous Membranes as Potential Therapeutic Systems with Analgesic Effect for Burn Care

MEMBRANES (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Critical Care Medicine

Short and long term mortality following massive burn injury (> 50% TBSA) in a UK burns centre

Harriet Walker et al.

Summary: This study aimed to determine the short and long term mortality rate at a UK burns center for patients with massive burn injuries. The results showed that self-inflicted burns had a higher mortality rate, but there were no subsequent successful suicide attempts after discharge from the hospital.

BURNS (2022)

添加到收藏夹

Article Environmental Sciences

Burn Wound Healing: Clinical Complications, Medical Care, Treatment, and Dressing Types: The Current State of Knowledge for Clinical Practice

Agnieszka Markiewicz-Gospodarek et al.

Summary: Burn wounds are complex injuries that are difficult to heal and are associated with high mortality rates, requiring multidirectional management including surgical activities and pharmacological treatment. This paper provides a comprehensive review of the current literature on burn wounds, covering classification, complications, medical care, and pharmacological treatment, as well as the latest innovations in dressings used for wound healing in medical practice.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

添加到收藏夹

Article Polymer Science

Locust bean gum-polyvinyl alcohol hydrogels: Synthesis, characterization, swelling behaviors, and mathematical models

Ghassan H. Matar et al.

Summary: LBG/PVA hydrogels were synthesized without toxic crosslinking agents, showing pH and temperature-responsive behavior. The hydrogels exhibited a maximum swelling ratio at 37 degrees C and non-Fickian diffusion dominated the swelling process. The Elmas model had better fits at 277 K and 298 K, while the Peppas model performed better at 310 K, indicating their potential as biomaterials for drug delivery applications.

JOURNAL OF APPLIED POLYMER SCIENCE (2022)

添加到收藏夹

Article Polymer Science

Cost Function Analysis Applied to Different Kinetic Release Models of Arrabidaea chica Verlot Extract from Chitosan/Alginate Membranes

Luis Concha et al.

Summary: This work focuses on the mathematical analysis of the controlled release of A. chica extract from chitosan/alginate membranes. The results indicate that the Weibull model provides the best simulation for the release profiles from the four tested membranes.

POLYMERS (2022)

添加到收藏夹

Review Chemistry, Medicinal

Mechanism and Application of Chitosan and Its Derivatives in Promoting Permeation in Transdermal Drug Delivery Systems: A Review

Jinqian Ma et al.

Summary: This paper reviewed the mechanisms and applications of chitosan and its derivatives in transdermal drug delivery. The permeation-promoting mechanisms, such as changing the structure of stratum corneum proteins and affecting intercellular lipids, were summarized. Various transdermal preparations containing chitosan and its derivatives, including nanoparticles and liposomes, were also discussed. Chitosan and its derivatives have excellent permeability-promoting property, good biocompatibility, and biodegradability, making them ideal materials for local transdermal drug delivery.

PHARMACEUTICALS (2022)

添加到收藏夹

Article Environmental Sciences

Comparing Peak Burn Injury Times and Characteristics in Australia and New Zealand

Rebecca Hong et al.

Summary: Burns are a significant cause of illness and death globally. Understanding the timing and causes of burns, as well as the differences between countries, can help in prevention efforts. This study analyzed data from the Burns Registry of Australia and New Zealand to review burn injuries from July 2009 to June 2021. It found that the majority of injuries occurred during specific peak times, with scalds being the most common cause, occurring between 6 PM to 7 PM in Australia and 5 PM to 6 PM in New Zealand.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

添加到收藏夹

Article Environmental Sciences

Healing Process, Pain, and Health-Related Quality of Life in Patients with Venous Leg Ulcers Treated with Fish Collagen Gel: A 12-Week Randomized Single-Center Study

Paulina Moscicka et al.

Summary: This study aimed to assess the effectiveness of fish skin collagen in patients with venous leg ulcers (VLUs) and its impact on healing, pain intensity, and quality of life. The results showed that the application of fish collagen gel improved the healing process and quality of life in VLUs patients, reducing physical complaints, pain, and local skin symptoms to the greatest extent.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Comparative Preclinical Study of Lidocaine and Mepivacaine in Resilient Hyaluronic Acid Fillers

Romain Brusini et al.

Summary: This study compared the influence of lidocaine and mepivacaine on fillers and found that they had similar effects, making both suitable as anesthetics for soft-tissue fillers.

PHARMACEUTICS (2022)

添加到收藏夹

Article Public, Environmental & Occupational Health

The epidemiological characteristic and trends of burns globally

Aobuliaximu Yakupu et al.

Summary: Globally, the rates of burn incidence, DALYs, and mortality, as well as the number of burn DALYs and death cases, will continue to decrease. However, there is an increasing tendency in the number of new burn cases globally. The EAPCs of burns in incidence, DALYs, and deaths show that the burden of burns is decreasing in most regions. The EAPCs also indicate that the prevention of burns depends not only on health spending per capita but also on the education level per capita and healthcare system performance. Higher health spending does not necessarily correspond to a higher UHC index; high efficiency in translating health spending into individuals' health gains is important.

BMC PUBLIC HEALTH (2022)

添加到收藏夹

Article Polymer Science

Electrospun Polycaprolactone (PCL) Degradation: An In Vitro and In Vivo Study

Juliana R. Dias et al.

Summary: PCL is widely used in tissue engineering due to its unique properties. PCL electrospun fiber meshes are expected to have a fast degradation rate. In vitro and in vivo studies showed that lipase can promote the degradation rate of PCL meshes up to 97% in a static medium, while the degradation rate was slower in vivo but the samples were well-integrated with the surrounding tissues.

POLYMERS (2022)

添加到收藏夹

Article Polymer Science

Evaluation of Physically and/or Chemically Modified Chitosan Hydrogels for Proficient Release of Insoluble Nystatin in Simulated Fluids

Andra-Cristina Enache et al.

Summary: This paper proposes chitosan-based physically or chemically cross-linked hydrogels for sustained release of micronized nystatin antifungal drug. The hydrogels exhibited mechanical properties similar to soft tissues and showed good potential for local delivery and treatment of fungal infections.

GELS (2022)

添加到收藏夹

Article Polymer Science

Development of Nanogel Loaded with Lidocaine for Wound-Healing: Illustration of Improved Drug Deposition and Skin Safety Analysis

Amena Ali et al.

Summary: In this study, the wound-healing properties of lidocaine nanogel were investigated. The nanogel showed antioxidant and neutrophilic modulatory potential. The evaluation of nanogel on various parameters demonstrated its effectiveness in wound healing, with no visible damage to the skin and improved drug deposition. The study provides substantial evidence for the potential use of this nanogel in healing wounds effectively.

GELS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Preparation of a Branch-Fruit structure chitosan nanofiber physical hydrogels with high mechanical strength and pH-responsive controlled drug release properties

Ying Wen et al.

Summary: Researchers have developed a chitosan nanofiber/hyaluronic acid/beta-glycerophosphate disodium drug-loaded hydrogel with excellent mechanical properties and cell adhesion properties. The hydrogel can be used for tumor-specific treatment and exhibits pH sensitivity.

RSC ADVANCES (2022)

添加到收藏夹

Article Polymer Science

Graphene Oxide-Reinforced Alginate Hydrogel for Controlled Release of Local Anesthetics: Synthesis, Characterization, and Release Studies

Cuong Hung Luu et al.

Summary: Lidocaine is a local anesthetic that has gained attention, but its use is limited by side effects. This study developed a hydrogel formulation comprising sodium alginate and graphene oxide for prolonged release of lidocaine. The addition of graphene oxide to the hydrogel resulted in a sustained release of lidocaine. In vitro and in vivo experiments confirmed the biocompatibility, in-situ gelation, and biodegradability of the hydrogel.

GELS (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Amphiphilic Alkylated Pectin Hydrogels for Enhanced Topical Delivery of Fusidic Acid: Formulation and In Vitro Investigation

Mohammad F. Bostanudin

Summary: Hydrogels made of alkylated pectin have shown promise in topical drug distribution. The alkylated pectin hydrogels exhibited lower swelling percentage and slower release of fusidic acid compared to native pectin hydrogels. Higher pH enhanced the swelling percentage and drug release. In vitro experiments demonstrated that alkylated pectin hydrogels facilitated a 1.5-fold higher rate of fusidic acid penetration through the membrane compared to native pectin hydrogels.

SCIENTIA PHARMACEUTICA (2022)

添加到收藏夹

Review Medicine, General & Internal

Effectiveness of Topical Anesthetics in Pain Management for Dermal Injuries: A Systematic Review

Juan Manuel Navarro-Rodriguez et al.

Summary: Topical anesthesia is effective in relieving pain associated with dermal injuries, showing statistically significant differences when compared to a placebo or other anesthetics. The results indicate that topical anesthesia is safer and offers satisfactory pain relief compared to traditional anesthesia methods.

JOURNAL OF CLINICAL MEDICINE (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Preparation and In Vivo Evaluation of a Lidocaine Self-Nanoemulsifying Ointment with Glycerol Monostearate for Local Delivery

Ji-Hyun Kang et al.

Summary: The study improved the formulation of lidocaine ointments through nanoemulsion technology, resulting in deeper skin penetration of lidocaine and enhanced local anesthetic effects.

PHARMACEUTICS (2021)

添加到收藏夹

Article Materials Science, Ceramics

Fabrication and characterization of freeze dried strontium-doped bioactive glasses/chitosan composite scaffolds for biomedical engineering

Chao-Kuang Kuo et al.

Summary: The study prepared Sr-BG/chitosan composite scaffolds using freeze drying technique and characterized the microstructure, swelling, degradation behaviors, in vitro bioactivity, and cytotoxicity. The results demonstrated the potential of this composite scaffold for tissue engineering applications with improved bioactivity and cell viability.

JOURNAL OF ASIAN CERAMIC SOCIETIES (2021)

添加到收藏夹

Article Emergency Medicine

Antibacterial polysaccharide-based hydrogel dressing containing plant essential oil for burn wound healing

Huanhuan Wang et al.

Summary: This study successfully developed a porous CBM/CMC/EEO hydrogel with high antibacterial activity, good swelling properties, optimal rheological behavior, excellent water retention and water vapor transmission performance, and significant effects on skin repair in vitro and in vivo. The results suggest that the CBM/CMC/EEO hydrogel has the potential to be a promising burn dressing material for skin burn repair.

BURNS & TRAUMA (2021)

添加到收藏夹

Review Medicine, General & Internal

Utility of lidocaine as a topical analgesic and improvements in patch delivery systems

Jeff Gudin et al.

POSTGRADUATE MEDICINE (2020)

添加到收藏夹

Article Polymer Science

Chitosan-Sulfated Titania Composite Membranes with Potential Applications in Fuel Cell: Influence of Cross-Linker Nature

Andra-Cristina Humelnicu et al.

POLYMERS (2020)

添加到收藏夹

Review Anesthesiology

Local Anesthetic Systemic Toxicity (LAST) - a Review and Update

Sivasenthil Arumugam et al.

CURRENT ANESTHESIOLOGY REPORTS (2020)

添加到收藏夹

Review Anesthesiology

The use of atypical analgesics by intravenous infusion for acute pain: evidence base for lidocaine, ketamine and magnesium

David Hutchins et al.

ANAESTHESIA AND INTENSIVE CARE MEDICINE (2019)

添加到收藏夹

Article Chemistry, Analytical

FTIR spectroscopy studies on the spontaneous neutralization of chitosan acetate films by moisture conditioning

Reina Araceli Mauricio-Sanchez et al.

VIBRATIONAL SPECTROSCOPY (2018)

添加到收藏夹

Review Infectious Diseases

Incidence of methicillin resistant Staphylococcus aureus (MRSA) in burn intensive care unit: a systematic review

Tahir Mehmood Khan et al.

GERMS (2018)

添加到收藏夹

Article Polymer Science

Influence of freezing temperature and deacetylation degree on the performance of freeze-dried chitosan scaffolds towards cartilage tissue engineering

Lara Lopes Reys et al.

EUROPEAN POLYMER JOURNAL (2017)

添加到收藏夹

Article Pharmacology & Pharmacy

Evaluation of of lidocaine loaded clay based dermal patch systems

Srinath Rangappa et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2017)

添加到收藏夹

Article Materials Science, Biomaterials

Effect of inorganic/organic ratio and chemical coupling on the performance of porous silica/chitosan hybrid scaffolds

Daming Wang et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

添加到收藏夹

Article Polymer Science

Physico-chemical characterization of pH-sensitive N-Succinyl chitosan-g-poly (acrylamide-co-acrylic acid) hydrogels and in vitro drug release studies

Shahid Bashir et al.

POLYMER DEGRADATION AND STABILITY (2017)

添加到收藏夹

Article Dermatology

Enhanced wound-healing performance of a phyto-polysaccharide-enriched dressing - a preclinical small and large animal study

Chih-Hsin Wang et al.

INTERNATIONAL WOUND JOURNAL (2017)

添加到收藏夹

Review Dermatology

Chitin and chitosan: biopolymers for wound management

Rita Singh et al.

INTERNATIONAL WOUND JOURNAL (2017)

添加到收藏夹

Article Polymer Science

Fabrication of Multi-Layered Lidocaine and Epinephrine-Eluting PLGA/Collagen Nanofibers: In Vitro and In Vivo Study

Fu-Ying Lee et al.

POLYMERS (2017)

添加到收藏夹

Article Emergency Medicine

Epidemiology of burns and scalds in children presenting to the emergency department of a regional burns unit: a 7-year retrospective study

Ceri Elisabeth Battle et al.

BURNS & TRAUMA (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Injectable polysaccharide hybrid hydrogels as scaffolds for burn wound healing

Ziyi Li et al.

RSC ADVANCES (2015)

添加到收藏夹

Article Critical Care Medicine

Effectiveness of a topical local anaesthetic spray as analgesia for dressing changes: A double-blinded randomised pilot trial comparing an emulsion with an aqueous lidocaine formulation

Chiragkumar Desai et al.

BURNS (2014)

添加到收藏夹

Article Engineering, Chemical

Fitting approach to liquid-liquid displacement porosimetry based on the log-normal pore size distribution

Enrique Anton et al.

JOURNAL OF MEMBRANE SCIENCE (2014)

添加到收藏夹

Article Chemistry, Physical

Sustained Release of Lidocaine from Solvent-Free Biodegradable Poly[(d,l)-Lactide-co-Glycolide] (PLGA): In Vitro and In Vivo Study

Yi-Chuan Kau et al.

MATERIALS (2014)

添加到收藏夹

Article Dermatology

Review of the relationship between stress and wound healing: part 1

K. Solowiej et al.

Journal of Wound Care (2014)

添加到收藏夹

Review Emergency Medicine

History of burns: The past, present and the future

Kwang Chear Lee et al.

BURNS & TRAUMA (2014)

添加到收藏夹

Article Polymer Science

Polyether based amphiphiles for delivery of active components

Shilpi Gupta et al.

POLYMER (2012)

添加到收藏夹

Article Chemistry, Physical

An amphiphilic silicone-modified polysaccharide molecular hybrid with in situ forming of hierarchical superporous architecture upon swelling

Wei-Chen Huang et al.

SOFT MATTER (2012)

添加到收藏夹

Review Pharmacology & Pharmacy

Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems

Yao Fu et al.

EXPERT OPINION ON DRUG DELIVERY (2010)

添加到收藏夹

Review Clinical Neurology

What are the psychiatric sequelae of burn pain?

Shelley Wiechman Askay et al.

CURRENT PAIN AND HEADACHE REPORTS (2008)

添加到收藏夹

Review Chemistry, Applied

Chitosan-modifications and applications: Opportunities galore

V. K. Mourya et al.

REACTIVE & FUNCTIONAL POLYMERS (2008)

添加到收藏夹

Article Biochemistry & Molecular Biology

Interactions between alginate and chitosan biopolymers characterized using FTIR and XPS

Gwen Lawrie et al.

BIOMACROMOLECULES (2007)

添加到收藏夹

Article Crystallography

2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide, a low-temperature redetermination

Massimo Bambagiotti-Alberti et al.

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE (2007)

添加到收藏夹

Article Critical Care Medicine

An investigation on burn wound healing in rats with chitosan gel formulation containing epidermal growth factor

C Alemdaroglu et al.

BURNS (2006)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.