4.7 Article

Electrochemical Biosensors for Circulating Tumor DNA Detection

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

DNA Hairpins and Dumbbell-Wheel Transitions Amplified Walking Nanomachine for Ultrasensitive Nucleic Acid Detection

Peng Miao et al.

Summary: This study presents a concept of DNA bipedal walking nanomachine for direct nucleic acid assay. The DNA nanostructures transitions and pH-assisted detachable intermolecular design are utilized for the construction and regeneration of electrochemical biosensor. The feasibility of detecting ctDNA and SARS-CoV-2 RNA in clinical samples has been demonstrated.

ACS NANO (2022)

Article Chemistry, Multidisciplinary

Three-dimensional graphene-like homogeneous carbon architecture loaded with gold-platinum for the electrochemical detection of circulating tumor DNA

K. C. Chen et al.

Summary: This study developed a ctDNA electrochemical biosensor with a low detection limit and high selectivity by using 3D-GHC600 loaded with AuPt. The biosensor showed good performance in ctDNA detection through the layer-by-layer recognition of capture probes, target DNA, and signal probes to form a sandwich-like structure.

MATERIALS TODAY CHEMISTRY (2022)

Article Chemistry, Analytical

Electrochemical detection of ctDNA mutation in non-small cell lung cancer based on CRISPR/Cas12a system

Feng Liu et al.

Summary: In this study, an electrochemical biosensor based on the CRISPR/Cas12a system and MB/Fe3O4@COF/PdAu nanocomposites was developed for rapid, accurate, and cost-effective detection of ctDNA EGFR L858R. The biosensor exhibited high specificity, stability, and selectivity, and has the potential application in cancer diagnosis and prognosis.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

Review Pharmacology & Pharmacy

Electrochemical biosensors: a nexus for precision medicine

Thomas D. Pollard et al.

Summary: Precision medicine has great potential for improving patient quality of life through therapeutic drug monitoring (TDM), with electrochemical biosensors (ECBs) offering a cost-effective, portable, and highly sensitive solution to current TDM challenges. Emerging strategies for continuous drug monitoring are being explored to enhance the field's developments and outlook.

DRUG DISCOVERY TODAY (2021)

Article Chemistry, Multidisciplinary

Self-Assembly-Driven Nanomechanics in Porous Covalent Organic Framework Thin Films

Kaushik Dey et al.

Summary: This study investigates the mechanical behavior of different types of COF thin films by controlling the internal order and self-assembly of building blocks, revealing that defect density and the nature of supramolecular interactions play a significant role in determining the stress-strain behavior of the films.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Biophysics

A supersensitive silicon nanowire array biosensor for quantitating tumor marker ctDNA

Dujuan Li et al.

Summary: The FET biosensor based on uniform high-response silicon nanowire array studied in this research shows significant superiority in real-time, label-free, super-sensitive detection of PIK3CA E542K ctDNA, achieving ultralow detection limit of 10 aM and high selectivity in recognizing complementary target ctDNA. The biosensor also demonstrated potential for clinical applications by successfully detecting target ctDNA in human serum samples.

BIOSENSORS & BIOELECTRONICS (2021)

Article Chemistry, Analytical

A novel sandwich-type electrochemical biosensor enabling sensitive detection of circulating tumor DNA

Hongli Zhao et al.

Summary: A novel sandwich-type electrochemical biosensor was developed for sensitive detection of ctDNA using nanocomposites as signal probes' label. The sensor showed excellent detection performance with wide linear range and low detection limit, demonstrating promising practical applications in clinical ctDNA diagnosis.

MICROCHEMICAL JOURNAL (2021)

Article Nanoscience & Nanotechnology

Exploring the Limit of Multiplexed Near-Field Optical Trapping

Donato Conteduca et al.

Summary: Optical trapping has revolutionized the understanding of biology by manipulating cells and single molecules using optical forces. Moving to the near-field allows intense field gradients to trap very small particles such as DNA fragments, viruses, and vesicles. The next frontier in biomedical applications for optical nanotweezers is to trap multiple particles and study their heterogeneity, which can be achieved using dielectric metasurfaces.

ACS PHOTONICS (2021)

Article Genetics & Heredity

Ultra-Low DNA Input into Whole Genome Methylation Assays and Detection of Oncogenic Methylation and Copy Number Variants in Circulating Tumour DNA

Celina Whalley et al.

Summary: Through low input experiments, it was found that the Illumina Infinium HD methylation assay can detect methylation across different sample types, including ctDNA, down to an input of 10 ng. The results of differential methylation analysis did not vary significantly by DNA input in the blood and FFPE groups, but there were some differences in the ctDNA group, possibly due to enrichment for tumor material.

EPIGENOMES (2021)

Review Chemistry, Multidisciplinary

High-Performance Nucleic Acid Sensors for Liquid Biopsy Applications

Jagotamoy Das et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Analytical

Rapid and Sensitive Detection of Bisphenol A Based on Self-Assembly

Haoyue Luo et al.

MICROMACHINES (2020)

Review Materials Science, Multidisciplinary

Bicontinuous cubic phases in biological and artificial self-assembled systems

Congcong Cui et al.

SCIENCE CHINA-MATERIALS (2020)

Article Chemistry, Analytical

CRISPR-dCas9 powered impedimetric biosensor for label-free detection of circulating tumor DNAs

Zihni Onur Uygun et al.

ANALYTICA CHIMICA ACTA (2020)

Article Chemistry, Physical

Immobilization of unspecific peroxygenase expressed in Pichia pastoris by metal affinity binding

Sebastian Bormann et al.

MOLECULAR CATALYSIS (2020)

Article Chemistry, Analytical

Development of point-of-care nanobiosensors for breast cancers diagnosis

Majid Sharifi et al.

TALANTA (2020)

Article Biophysics

Developments in biosensors for CoV detection and future trends

Riccarda Antiochia

BIOSENSORS & BIOELECTRONICS (2020)

Article Nanoscience & Nanotechnology

Affinity Immobilization of Semiconductor Quantum Dots and Metal Nanoparticles on Cellulose Paper Substrates

Hyungki Kim et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Review Chemistry, Analytical

Emerging technologies in the design of peptide nucleic acids (PNAs) based biosensors

Maria Moccia et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2020)

Review Biophysics

Liquid biopsy of circulating tumor DNA and biosensor applications

Xuanying Li et al.

BIOSENSORS & BIOELECTRONICS (2019)

Article Biochemical Research Methods

A nanoflow cytometric strategy for sensitive ctDNA detection via magnetic separation and DNA self-assembly

Xingwei Zhai et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Circulating ctDNA methylation quantification of two DNA methyl transferases in papillary thyroid carcinoma

Fatemeh Khatami et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2019)

Article Multidisciplinary Sciences

ctDNA detected by ddPCR reveals changes in tumour load in metastatic malignant melanoma treated with bevacizumab

Rakel Brendsdal Forthun et al.

SCIENTIFIC REPORTS (2019)

Review Biochemistry & Molecular Biology

Surface Enhanced Raman Spectroscopy for DNA Biosensors-How Far Are We?

Edyta Pyrak et al.

MOLECULES (2019)

Article Chemistry, Multidisciplinary

ctDNA Detection Based on DNA Clutch Probes and Strand Exchange Mechanism

Huan Chang et al.

FRONTIERS IN CHEMISTRY (2018)

Article Materials Science, Multidisciplinary

Facile preparation of highly luminescent composites by polymer embedding of carbon dots derived from N-hydroxyphthalimide

Corneliu Sergiu Stan et al.

JOURNAL OF MATERIALS SCIENCE (2017)

Article Chemistry, Multidisciplinary

A Multiparticulate Delivery System for Potential Colonic Targeting Using Bovine Serum Albumin as a Model Protein

Bowen Jiang et al.

PHARMACEUTICAL RESEARCH (2017)

Review Chemistry, Analytical

Technologies for analysis of circulating tumour DNA: Progress and promise

Zhen Zou et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2017)

Review Engineering, Chemical

Electrochemical Biosensors: Electrode Development, Materials, Design, and Fabrication

Hayder A. Abdulbari et al.

CHEMBIOENG REVIEWS (2017)

Review Chemistry, Analytical

Towards DNA methylation detection using biosensors

Leila Syedmoradi et al.

ANALYST (2016)

Article Medical Laboratory Technology

SOX17 promoter methylation in plasma circulating tumor DNA of patients with non-small cell lung cancer

Ioanna Balgkouranidou et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2016)

Review Oncology

Methylated circulating tumor DNA in blood: power in cancer prognosis and response

Kristina Warton et al.

ENDOCRINE-RELATED CANCER (2016)

Article Chemistry, Multidisciplinary

DNA Clutch Probes for Circulating Tumor DNA Analysis

Jagotamoy Das et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Article Polymer Science

DETECTION OF ctDNA WITH WATER SOLUBLE TETRAPHENYLENE-BASED FLUORESCENCE PROBE

Jin Jiake et al.

ACTA POLYMERICA SINICA (2011)

Review Electrochemistry

Prospects of Nanobiomaterials for Biosensing

Ravindra P. Singh

INTERNATIONAL JOURNAL OF ELECTROCHEMISTRY (2011)

Article Chemistry, Multidisciplinary

Amplified electrocatalysis at DNA-modified nanowires

MA Lapierre-Devlin et al.

NANO LETTERS (2005)