4.6 Editorial Material

Treatment of Type 2 Diabetes With GLP-1 Receptor Agonists Among Patients With CKD

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Article Urology & Nephrology

Hemoglobin A1c Reduction With the GLP-1 Receptor Agonist Semaglutide Is Independent of Baseline eGFR: post hoc Analysis of the SUSTAIN and PIONEER Programs

David Z. I. Cherney et al.

Summary: This study analyzed the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1RAs), specifically semaglutide, in reducing hemoglobin A1c (HbA1c) levels in patients with type 2 diabetes across different levels of kidney function. The results showed that semaglutide effectively reduced HbA1c levels regardless of the baseline estimated glomerular filtration rate (eGFR), and also resulted in significant weight loss.

KIDNEY INTERNATIONAL REPORTS (2022)