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Digital Pills with Ingestible Sensors: Patent Landscape Analysis

PHARMACEUTICALS (2022)

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Review Urology & Nephrology

Detecting, preventing and treating non-adherence to immunosuppression after kidney transplantation

Ilaria Gandolfini et al.

Summary: Medication non-adherence is a significant issue in kidney transplantation, and the best strategies for diagnosis, prevention, and treatment are still unclear. Non-adherence can be intentional or unintentional, and diagnosis can rely on direct or indirect methods. Identifying individual risk factors may personalize the treatment approach. Short-term effects of various strategies have been observed, but long-term effects remain unclear.

CLINICAL KIDNEY JOURNAL (2022)

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Article Public, Environmental & Occupational Health

Real-World User Experiences with a Digital Pill System to Measure PrEP Adherence: Perspectives from MSM with Substance Use

Peter R. Chai et al.

Summary: Qualitative interviews were conducted with 15 MSM to investigate their experiences using a digital pill system (DPS) to measure PrEP adherence, finding that most participants found the system easy to integrate into their daily routines and suggested some improvements for long-term use.

AIDS AND BEHAVIOR (2022)

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Review Health Care Sciences & Services

Ingestible electronic sensors to measure instantaneous medication adherence: A narrative review

Peter R. Chai et al.

Summary: Digital pill systems are a novel and direct method of measuring adherence, providing instantaneous adherence support. Research based on clinical trials and qualitative investigations has shown the potential of digital pill systems in measuring medication adherence and improving adherence.

DIGITAL HEALTH (2022)

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Review Medicine, General & Internal

Arterial hypertension

Sofie Brouwers et al.

Summary: Arterial hypertension is a major contributor to the global burden of disease, but disease control remains poor. Diagnosis and treatment of hypertension should be based on a combination of various guidelines, with equal emphasis on pharmacological treatment and lifestyle adjustments. Device-based therapies such as renal denervation are rapidly evolving to expand therapeutic options.

LANCET (2021)

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Review Immunology

Adherence to immunosuppression in adult heart transplant recipients: A systematic review

Tasmeen Hussain et al.

Summary: This systematic review explores the current landscape of adherence to immunosuppression in adult heart transplant patients, highlighting variations in baseline adherence estimates, significant correlates to nonadherence, and potential health outcomes associated with nonadherence. Simplified dosing regimens and mobile phone interventions were found to improve adherence. Further high-quality studies are needed to investigate strategies for improving adherence.

TRANSPLANTATION REVIEWS (2021)

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Article

Drug resistant tuberculosis: Current scenario and impending challenges

Shivendra Singh Dewhare

Indian Journal of Tuberculosis (2021)

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Article Communication

Ingestible sensors, data, and pharmaceuticals: Subjectivity in the era of digital mental health

Jacinthe Flore

Summary: This article explores a significant innovation in digital mental health - Abilify MyCite. It examines the production of subjectivity in the era of digital mental health by viewing it as a combination of technologies.

NEW MEDIA & SOCIETY (2021)

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Review Ethics

Digital pills: a scoping review of the empirical literature and analysis of the ethical aspects

Andrea Martani et al.

BMC MEDICAL ETHICS (2020)

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Article Psychiatry

Detection of Behavioral Anomalies in Medication Adherence Patterns Among Patients With Serious Mental Illness Engaged With a Digital Medicine System

Jonathan Knights et al.

JMIR MENTAL HEALTH (2020)

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Review Pharmacology & Pharmacy

Ingestible Sensors and Medication Adherence: Focus on Use in Serious Mental Illness

Azita Alipour et al.

PHARMACY (2020)

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Letter Medicine, General & Internal

Financial toxicity of cancer treatment: Moving the discussion from acknowledgement of the problem to identifying solutions

Aakash Desai et al.

ECLINICALMEDICINE (2020)

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Review Anesthesiology

Chronic pain: a review of its epidemiology and associated factors in population-based studies

Sarah E. E. Mills et al.

BRITISH JOURNAL OF ANAESTHESIA (2019)

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Article Endocrinology & Metabolism

Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition

Pouya Saeedi et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2019)

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Article Medicine, General & Internal

Hummingbird Study: a study protocol for a multicentre exploratory trial to assess the acceptance and performance of a digital medicine system in adults with schizophrenia, schizoaffective disorder or first-episode psychosis

J. Corey Fowler et al.

BMJ OPEN (2019)

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Article Medicine, General & Internal

Wirelessly observed therapy compared to directly observed therapy to confirm and support tuberculosis treatment adherence: A randomized controlled trial

Sara H. Browne et al.

PLOS MEDICINE (2019)

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Review Medicine, General & Internal

Economic impact of medication non-adherence by disease groups: a systematic review

Rachelle Louise Cutler et al.

BMJ OPEN (2018)

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Article Health Care Sciences & Services

Digital Pills to Measure Opioid Ingestion Patterns in Emergency Department Patients With Acute Fracture Pain: A Pilot Study

Peter R. Chai et al.

JOURNAL OF MEDICAL INTERNET RESEARCH (2017)

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Article Health Care Sciences & Services

Effectiveness of Digital Medicines to Improve Clinical Outcomes in Patients with Uncontrolled Hypertension and Type 2 Diabetes: Prospective, Open-Label, Cluster-Randomized Pilot Clinical Trial

Juan Frias et al.

JOURNAL OF MEDICAL INTERNET RESEARCH (2017)

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Review Medicine, General & Internal

Why do psychiatric patients stop antipsychotic medication? A systematic review of reasons for nonadherence to medication in patients with serious mental illness

Dawn I. Velligan et al.

PATIENT PREFERENCE AND ADHERENCE (2017)

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Review Chemistry, Multidisciplinary

Ingestible Sensors

Kourosh Kalantar-zadeh et al.

ACS SENSORS (2017)

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Article Psychology, Clinical

Optimization of a Digital Medicine System in Psychiatry

Shashank Rohatagi et al.

JOURNAL OF CLINICAL PSYCHIATRY (2016)

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Review Gastroenterology & Hepatology

Hepatitis C Virus: A Review of Treatment Guidelines, Cost-effectiveness, and Access to Therapy

Shaina M. Lynch et al.

JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY (2016)

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Letter Peripheral Vascular Disease

Hypertension Assessment and Management: Role for Digital Medicine

Peter Godbehere et al.

JOURNAL OF CLINICAL HYPERTENSION (2014)

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Article Psychology, Clinical

First Experience With a Wireless System Incorporating Physiologic Assessments and Direct Confirmation of Digital Tablet Ingestions in Ambulatory Patients With Schizophrenia or Bipolar Disorder

John M. Kane et al.

JOURNAL OF CLINICAL PSYCHIATRY (2013)

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Article Immunology

Medication Adherence Assessment: High Accuracy of the New Ingestible Sensor System in Kidney Transplants

Ute Eisenberger et al.

TRANSPLANTATION (2013)

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