Impact of Early Limitation of Therapeutic Effort in Elderly COVID-19 Patients Admitted to the Intensive Care Unit-A Cohort Study

Article Medicine, General & Internal

Risk factors for severe COVID-19 disease and death in patients aged 70 and over: a retrospective observational cohort study

Katleen Fagard et al.

Summary: The introduction of the Clinical Frailty Scale in non-ICU COVID-19 units revealed that CFS and cognitive decline are independent risk factors for in-hospital mortality in older patients with COVID-19.

ACTA CLINICA BELGICA (2022)

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Article Health Care Sciences & Services

The PALliative MUlticenter Study in Intensive Care (PalMuSIC). Results From a Multicenter Study Addressing Frailty and Palliative Care Interventions in Intensive Care Units in Portugal

Iuri Correia et al.

Summary: Frail patients are more likely to receive organ support therapy, but are also more likely to have limitations on therapeutic efforts. The 6-month mortality rate is higher in frail patients, yet only a small percentage of them receive palliative care.

JOURNAL OF PALLIATIVE CARE (2022)

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Article Critical Care Medicine

Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in intensive care units in the Czech Republic

Tereza Prokopova et al.

Summary: This study investigated the level of moral distress in end-of-life care practices during the COVID-19 pandemic in intensive care units (ICUs) in the Czech Republic. The results showed that more than half of the healthcare providers experienced moral distress during this period, with perceiving inappropriate care and patients dying without dignity being the major sources. Improving the decision-making process and communication could lead to a better ethical and safety climate.

CRITICAL CARE (2022)

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Article Critical Care Medicine

Hospital-Acquired Infections in Critically Ill Patients With COVID-19

Giacomo Grasselli et al.

Summary: Critically ill patients with COVID-19 are at high risk for hospital-acquired infections (HAIs), especially ventilator-associated pneumonia (VAP) and bloodstream infections (BSIs) caused by multidrug-resistant organisms. HAIs prolong mechanical ventilation and hospitalization, and those complicated by septic shock nearly double mortality rate.

CHEST (2021)

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Letter Critical Care Medicine

Long-term mortality of elderly patients after intensive care unit admission for COVID-19

Antoine Guillon et al.

INTENSIVE CARE MEDICINE (2021)

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Article Critical Care Medicine

Characteristics, management, and prognosis of elderly patients with COVID-19 admitted in the ICU during the first wave: insights from the COVID-ICU study Prognosis of COVID-19 elderly critically ill patients in the ICU

Martin Dres et al.

Summary: The COVID-19 pandemic has placed a heavy burden on healthcare resources, particularly for older patients over 70 years old admitted to the ICU. The mortality rate at Day-90 was 46%, with worse outcomes for patients over 80 years old or those intubated upon ICU admission.

ANNALS OF INTENSIVE CARE (2021)

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Article Critical Care Medicine

Variations in end-of-life practices in intensive care units worldwide (Ethicus-2): a prospective observational study

Alexander Avidan et al.

Summary: This study revealed global disparities in end-of-life practices among ICU patients. Limitation of life-sustaining treatment is common worldwide with regional variability, and recognizing these differences may help improve end-of-life care globally.

LANCET RESPIRATORY MEDICINE (2021)

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Article Critical Care Medicine

The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study

Christian Jung et al.

Summary: This study aimed to determine the interaction of frailty and age in elderly COVID-19 ICU patients, finding that frailty was independently associated with lower survival rates. Frail patients were more likely to have treatment limitations and less likely to receive mechanical ventilation.

CRITICAL CARE (2021)

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Letter Medicine, General & Internal