期刊
JOURNAL OF MICROBIOLOGY
卷 54, 期 2, 页码 131-135出版社
MICROBIOLOGICAL SOCIETY KOREA
DOI: 10.1007/s12275-016-5311-9
关键词
Streptomyces sp.; new compounds; antibacterial activity; nematicidal activity
类别
资金
- 973 Program of China [2013CB127505]
- NSFC [31360028, 31560016]
- Young Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI023]
- Natural Science Foundation of Yunnan Province [2013FB003]
The Actinomycete strain P294 was isolated from soil and identified as Streptomyces sp. based upon the results of 16S rRNA sequence analysis. Three compounds obtained from the solid fermentation products of this strain have been determined by 1D, 2D NMR and HRMS experiments. These compounds include two new compounds angumycinones C (1) and D (2), and the known compound X-14881 E (3). All compounds were assayed for antibacterial and nematicidal activity. The results showed the three compounds had different degrees of inhibitory activity against several target bacteria but no significant toxicity against the nematode Caenorhabditis elegans.
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