相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The emerging roles of circRNAs in cancer and oncology
Lasse S. Kristensen et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2022)
Targeting cancer metabolism in the era of precision oncology
Zachary E. Stine et al.
NATURE REVIEWS DRUG DISCOVERY (2022)
Histone lactylation: epigenetic mark of glycolytic switch
Xiaofeng Dai et al.
TRENDS IN GENETICS (2022)
Hallmarks of Cancer: New Dimensions
Douglas Hanahan
CANCER DISCOVERY (2022)
Mutant IDH Inhibits IFNγ-TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma
Meng-Ju Wu et al.
CANCER DISCOVERY (2022)
Spatial omics: Navigating to the golden era of cancer research
Yingcheng Wu et al.
CLINICAL AND TRANSLATIONAL MEDICINE (2022)
A plant immune protein enables broad antitumor response by rescuing microRNA deficiency
Ye Qi et al.
CELL (2022)
TET3 promotes AML growth and epigenetically regulates glucose metabolism and leukemic stem cell associated pathways
Alex Jose Pulikkottil et al.
LEUKEMIA (2022)
Oncometabolites drive tumorigenesis by enhancing protein acylation: from chromosomal remodelling to nonhistone modification
Yidian Fu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2022)
Ivosidenib and Azacitidine in IDH1-Mutated Acute Myeloid Leukemia
Pau Montesinos et al.
NEW ENGLAND JOURNAL OF MEDICINE (2022)
Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor
Tengrui Zhang et al.
EBIOMEDICINE (2022)
Novel insights into RB1 mutation
Yiran Yao et al.
CANCER LETTERS (2022)
Design of the VIALE-M phase III trial of venetoclax and oral azacitidine maintenance therapy in acute myeloid leukemia
Vladimir Ivanov et al.
FUTURE ONCOLOGY (2022)
Azacitidine plus venetoclax in patients with high-risk myelodysplastic syndromes or chronic myelomonocytic leukaemia: phase 1 results of a single-centre, dose- escalation, dose-expansion, phase 1-2 study
Alexandre Bazinet et al.
LANCET HAEMATOLOGY (2022)
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics
Qi Liu et al.
NATURE METABOLISM (2022)
Role of main RNA modifications in cancer: N6-methyladenosine, 5-methylcytosine, and pseudouridine
Chen Xue et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)
Systematic Proteome and Lysine Succinylome Analysis Reveals Enhanced Cell Migration by Hyposuccinylation in Esophageal Squamous Cell Carcinoma
Zhenchang Guo et al.
MOLECULAR & CELLULAR PROTEOMICS (2021)
Non-coding RNAs: the new central dogma of cancer biology
Phei Er Saw et al.
SCIENCE CHINA-LIFE SCIENCES (2021)
ALKBH5 Inhibited Cell Proliferation and Sensitized Bladder Cancer Cells to Cisplatin by m6A-CK2α-Mediated Glycolysis
Hao Yu et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2021)
Non-coding RNAs and potential therapeutic targeting in cancer
Shusuke Toden et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2021)
Targeting p300/CBP Attenuates Hepatocellular Carcinoma Progression through Epigenetic Regulation of Metabolism
Ling-Yan Cai et al.
CANCER RESEARCH (2021)
Integrated Molecular Characterization of Fumarate Hydratase-deficient Renal Cell Carcinoma
Guangxi Sun et al.
CLINICAL CANCER RESEARCH (2021)
m6A RNA methylation: from mechanisms to therapeutic potential
P. Cody He et al.
EMBO JOURNAL (2021)
Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis
Guang Yang et al.
EMBO REPORTS (2021)
Epigenetic Alterations in the Gastrointestinal Tract: Current and Emerging Use for Biomarkers of Cancer
William M. Grady et al.
GASTROENTEROLOGY (2021)
F. nucleatum targets lncRNA ENO1-IT1 to promote glycolysis and oncogenesis in colorectal cancer
Jie Hong et al.
GUT (2021)
HBXIP drives metabolic reprogramming in hepatocellular carcinoma cells via METTL3-mediated m6A modification of HIF-1α
Nanmu Yang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2021)
Mutant Isocitrate Dehydrogenase 1 Inhibitor Ivosidenib in Combination With Azacitidine for Newly Diagnosed Acute Myeloid Leukemia
Courtney D. DiNardo et al.
JOURNAL OF CLINICAL ONCOLOGY (2021)
Circular RNA circLMO7 acts as a microRNA-30a-3p sponge to promote gastric cancer progression via the WNT2/β-catenin pathway
Jiacheng Cao et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
Ying Qing et al.
MOLECULAR CELL (2021)
Gene regulation by long non-coding RNAs and its biological functions
Luisa Statello et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)
MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer
Jing Han et al.
ONCOGENE (2021)
EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma
Runping Fang et al.
NATURE COMMUNICATIONS (2021)
Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death
Vicente Fresquet et al.
CANCER DISCOVERY (2021)
Decitabine and venetoclax for IDH1/2-mutated acute myeloid leukemia
Sangeetha Venugopal et al.
AMERICAN JOURNAL OF HEMATOLOGY (2021)
HDAC11 Regulates Glycolysis through the LKB1/AMPK Signaling Pathway to Maintain Hepatocellular Carcinoma Stemness
Lei Bi et al.
CANCER RESEARCH (2021)
Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial
Courtney D. DiNardo et al.
LANCET ONCOLOGY (2021)
Succinylation of H3K122 destabilizes nucleosomes and enhances transcription
Lara Zorro Shahidian et al.
EMBO REPORTS (2021)
Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states
Ronan Chaligne et al.
NATURE GENETICS (2021)
Long noncoding RNA LINC00518 induces radioresistance by regulating glycolysis through an miR-33a-3p/HIF-1α negative feedback loop in melanoma
Yan Liu et al.
CELL DEATH & DISEASE (2021)
circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression
Yingkuan Liang et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2021)
Understanding the Function of Mammalian Sirtuins and Protein Lysine Acylation
Miao Wang et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 90, 2021 (2021)
USP48 Is Upregulated by Mettl14 to Attenuate Hepatocellular Carcinoma via Regulating SIRT6 Stabilization
Lutao Du et al.
CANCER RESEARCH (2021)
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance
Yi Liu et al.
CELL METABOLISM (2021)
Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer
Ser Yue Loo et al.
SCIENCE ADVANCES (2021)
Circ-MBOAT2 knockdown represses tumor progression and glutamine catabolism by miR-433-3p/GOT1 axis in pancreatic cancer
Xiaoxiao Zhou et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)
mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
Elodie Villa et al.
MOLECULAR CELL (2021)
Cell-programmed nutrient partitioning in the tumour microenvironment
Bradley Reinfeld et al.
NATURE (2021)
WNT/β-catenin-suppressed FTO expression increases m6A of c-Myc mRNA to promote tumor cell glycolysis and tumorigenesis
Xueying Yang et al.
CELL DEATH & DISEASE (2021)
LncRNA GIRGL drives CAPRIN1-mediated phase separation to suppress glutaminase-1 translation under glutamine deprivation
Ruijie Wang et al.
SCIENCE ADVANCES (2021)
N6-methyladenosine Steers RNA Metabolism and Regulation in Cancer
Shenghua Dong et al.
CANCER COMMUNICATIONS (2021)
The role of the HIF-1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer
Jing-Zi Wang et al.
CANCER COMMUNICATIONS (2021)
Histone succinylation and its function on the nucleosome
Jiayi Liu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)
Long non-coding RNA SLC2A1-AS1 induced by GLI3 promotes aerobic glycolysis and progression in esophageal squamous cell carcinoma by sponging miR-378a-3p to enhance Glut1 expression
Hongtao Liu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)
被撤回的出版物: LNCAROD enhances hepatocellular carcinoma malignancy by activating glycolysis through induction of pyruvate kinase isoform PKM2 (Retracted article. See vol. 42, 2023)
Guizhi Jia et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)
CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner
Xin Liu et al.
MOLECULAR CANCER (2021)
Circular RNA circRNF13 inhibits proliferation and metastasis of nasopharyngeal carcinoma via SUMO2
Yongzhen Mo et al.
MOLECULAR CANCER (2021)
Novel circular RNA circSLIT2 facilitates the aerobic glycolysis of pancreatic ductal adenocarcinoma via miR-510-5p/c-Myc/LDHA axis
Hua Guan et al.
CELL DEATH & DISEASE (2021)
C5aR1-positive neutrophils promote breast cancer glycolysis through WTAP-dependent m6A methylation of ENO1
Baochi Ou et al.
CELL DEATH & DISEASE (2021)
CircC16orf62 promotes hepatocellular carcinoma progression through the miR-138-5p/PTK2/AKT axis
Shuai Zhang et al.
CELL DEATH & DISEASE (2021)
METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N6-methyladenosine-dependent YTHDF binding
Wei Wang et al.
NATURE COMMUNICATIONS (2021)
Lactate Modulates Cellular Metabolism Through Histone Lactylation-Mediated Gene Expression in Non-Small Cell Lung Cancer
Jun Jiang et al.
FRONTIERS IN ONCOLOGY (2021)
The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry
Xujun Liu et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)
Roles and Regulation of TET Enzymes in Solid Tumors
Julie K. Bray et al.
TRENDS IN CANCER (2021)
Histone lactylation drives oncogenesis by facilitating m6A reader protein YTHDF2 expression in ocular melanoma
Jie Yu et al.
GENOME BIOLOGY (2021)
Risk SNP-induced lncRNA-SLCC1 drives colorectal cancer through activating glycolysis signaling
Tingting Yan et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)
The metabolism of cancer cells during metastasis
Gabriele Bergers et al.
NATURE REVIEWS CANCER (2021)
Epigenetic silencing of LncRNA LINC00261 promotes c-myc-mediated aerobic glycolysis by regulating miR-222-3p/HIPK2/ERK axis and sequestering IGF2BP1
Shuyu Zhai et al.
ONCOGENE (2021)
New insights into molecules and pathways of cancer metabolism and therapeutic implications
Zhenye Tang et al.
CANCER COMMUNICATIONS (2021)
Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma
Shuai Wu et al.
NATURE CANCER (2021)
Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma
Chuanjie Zhang et al.
THERANOSTICS (2021)
METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance
Qiang Wang et al.
GUT (2020)
Synthetic lethality as an engine for cancer drug target discovery
Alan Huang et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
A novel KDM5A/MPC-1 signaling pathway promotes pancreatic cancer progression via redirecting mitochondrial pyruvate metabolism
Jiujie Cui et al.
ONCOGENE (2020)
Greasing the Wheels of the Cancer Machine: The Role of Lipid Metabolism in Cancer
Marteinn Thor Snaebjornsson et al.
CELL METABOLISM (2020)
AMPK and TOR: The Yin and Yang of Cellular Nutrient Sensing and Growth Control
Asier Gonzalez et al.
CELL METABOLISM (2020)
ATP-Citrate Lyase Epigenetically Potentiates Oxidative Phosphorylation to Promote Melanoma Growth and Adaptive Resistance to MAPK Inhibition
Weinan Guo et al.
CLINICAL CANCER RESEARCH (2020)
Epigenetics of colorectal cancer: biomarker and therapeutic potential
Gerhard Jung et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)
Circular RNA circRNF20 promotes breast cancer tumorigenesis and Warburg effect through miR-487a/HIF-1α/HK2
Lili Cao et al.
CELL DEATH & DISEASE (2020)
Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells
Inigo San-Millan et al.
FRONTIERS IN ONCOLOGY (2020)
KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer
Hunain Alam et al.
CANCER CELL (2020)
Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
Kulandaimanuvel Antony Michealraj et al.
CELL (2020)
HIF1A activates the transcription of lncRNA RAET1K to modulate hypoxia-induced glycolysis in hepatocellular carcinoma cells via miR-100-5p
Yufan Zhou et al.
CELL DEATH & DISEASE (2020)
N6-methyladenosine regulates glycolysis of cancer cells through PDK4
Zihan Li et al.
NATURE COMMUNICATIONS (2020)
Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming
Jia Liu et al.
NATURE COMMUNICATIONS (2020)
m6A-dependent glycolysis enhances colorectal cancer progression
Chaoqin Shen et al.
MOLECULAR CANCER (2020)
Novel insight into the regulatory roles of diverse RNA modifications: Re-defining the bridge between transcription and translation
Shi Hanhan et al.
MOLECULAR CANCER (2020)
Extracellular serine controls epidermal stem cell fate and tumour initiation
Sanjeethan C. Baksh et al.
NATURE CELL BIOLOGY (2020)
Metabolic regulation of epigenetic remodeling in immune cells
Emily C. Britt et al.
CURRENT OPINION IN BIOTECHNOLOGY (2020)
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models
Trang Thi Thu Nguyen et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
EZH2: a novel target for cancer treatment
Ran Duan et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Oncometabolites suppress DNA repair by disrupting local chromatin signalling
Parker L. Sulkowski et al.
NATURE (2020)
Cholangiocarcinoma 2020: the next horizon in mechanisms and management
Jesus M. Banales et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)
Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia
C. D. DiNardo et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Epigenetic Therapies for Cancer
Susan E. Bates
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Semisynthesis of site-specifically succinylated histone reveals that succinylation regulates nucleosome unwrapping rate and DNA accessibility
Yihang Jing et al.
NUCLEIC ACIDS RESEARCH (2020)
In Colorectal Cancer Cells With Mutant KRAS, SLC25A22-Mediated Glutaminolysis Reduces DNA Demethylation to Increase WNT Signaling, Stemness, and Drug Resistance
Chi Chun Wong et al.
GASTROENTEROLOGY (2020)
Circular RNA circSLC25A16 contributes to the glycolysis of non-small-cell lung cancer through epigenetic modification
Hong Shangguan et al.
CELL DEATH & DISEASE (2020)
Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2
Chunqing Wang et al.
NATURE COMMUNICATIONS (2020)
Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth
Mari B. Ishak Gabra et al.
NATURE COMMUNICATIONS (2020)
The evolving metabolic landscape of chromatin biology and epigenetics
Ziwei Dai et al.
NATURE REVIEWS GENETICS (2020)
The m(6)A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor
Yiren Xiao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma
Mayinuer Maitituoheti et al.
CELL REPORTS (2020)
10-day decitabine with venetoclax for newly diagnosed intensive chemotherapy ineligible, and relapsed or refractory acute myeloid leukaemia: a single-centre, phase 2 trial
Courtney D. DiNardo et al.
LANCET HAEMATOLOGY (2020)
CircCDKN2B-AS1 interacts with IMP3 to stabilize hexokinase 2 mRNA and facilitate cervical squamous cell carcinoma aerobic glycolysis progression
Yanan Zhang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
Circular RNA: metabolism, functions and interactions with proteins
Wei-Yi Zhou et al.
MOLECULAR CANCER (2020)
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing
Sara Parsa et al.
NATURE CANCER (2020)
NAD+metabolism: pathophysiologic mechanisms and therapeutic potential
Na Xie et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Role of RNA modifications in cancer
Isaia Barbieri et al.
NATURE REVIEWS CANCER (2020)
N6-methyladenosine-induced ERR. triggers chemoresistance of cancer cells through upregulation of ABCB1 and metabolic reprogramming
Zhuojia Chen et al.
THERANOSTICS (2020)
The PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism
Gerta Hoxhaj et al.
NATURE REVIEWS CANCER (2020)
Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers
Hideaki Ogiwara et al.
CANCER CELL (2019)
Increased Serine and One-Carbon Pathway Metabolism by PKCλ/l Deficiency Promotes Neuroendocrine Prostate Cancer
Miguel Reina-Campos et al.
CANCER CELL (2019)
The Landscape of Circular RNA in Cancer
Josh N. Vo et al.
CELL (2019)
ACOT12-Dependent Alteration of Acetyl-CoA Drives Hepatocellular Carcinoma Metastasis by Epigenetic Induction of Epithelial-Mesenchymal Transition
Ming Lu et al.
CELL METABOLISM (2019)
The circular RNome of primary breast cancer
Marcel Smid et al.
GENOME RESEARCH (2019)
Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer
Jianan Chen et al.
MOLECULAR CANCER (2019)
Lactate: A Metabolic Driver in the Tumour Landscape
Luigi Ippolito et al.
TRENDS IN BIOCHEMICAL SCIENCES (2019)
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia
Yue Huang et al.
CANCER CELL (2019)
Long non-coding RNA FGF13-AS1 inhibits glycolysis and sternness properties of breast cancer cells through FGF13-AS1/IGF2BPs/Myc feedback loop
Fei Ma et al.
CANCER LETTERS (2019)
Circular RNA MAT2B Promotes Glycolysis and Malignancy of Hepatocellular Carcinoma Through the miR-338-3p/PKM2 Axis Under Hypoxic Stress
Qing Li et al.
HEPATOLOGY (2019)
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts
Mark A. Eckert et al.
NATURE (2019)
Methionine is a metabolic dependency of tumor-initiating cells
Zhenxun Wang et al.
NATURE MEDICINE (2019)
CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress
Qidong Li et al.
CELL METABOLISM (2019)
Past, present, and future of circRNAs
Ines Lucia Patop et al.
EMBO JOURNAL (2019)
MTHFD2 links RNA methylation to metabolic reprogramming in renal cell carcinoma
Nathanael H. Green et al.
ONCOGENE (2019)
Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Zhimin Gu et al.
CANCER DISCOVERY (2019)
LINC00184 silencing inhibits glycolysis and restores mitochondrial oxidative phosphorylation in esophageal cancer through demethylation of PTEN
Weihao Li et al.
EBIOMEDICINE (2019)
Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies
Chan-Wang J. Lio et al.
BLOOD (2019)
Should we consider subcellular compartmentalization of metabolites, and if so, how do we measure them?
Kathryn E. Wellen et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2019)
LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis
Qian Hua et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
α-Ketoglutarate links p53 to cell fate during tumour suppression
John P. Morris et al.
NATURE (2019)
The biogenesis, biology and characterization of circular RNAs
Lasse S. Kristensen et al.
NATURE REVIEWS GENETICS (2019)
The diverse roles of DNA methylation in mammalian development and disease
Maxim V. C. Greenberg et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating β-catenin/c-Myc signaling
Juan Cai et al.
CELL DEATH & DISEASE (2019)
The Role of Non-coding RNAs in Oncology
Frank J. Slack et al.
CELL (2019)
Therapeutic targeting of circ-CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression
Huanhuan Li et al.
EMBO MOLECULAR MEDICINE (2019)
Inducing and exploiting vulnerabilities for the treatment of liver cancer
Cun Wang et al.
NATURE (2019)
Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs
William A. Flavahan et al.
NATURE (2019)
Metabolic regulation of gene expression by histone lactylation
Di Zhang et al.
NATURE (2019)
CircRNA-ENO1 promoted glycolysis and tumor progression in lung adenocarcinoma through upregulating its host gene ENO1
Jiayu Zhou et al.
CELL DEATH & DISEASE (2019)
LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
Jiayin Tang et al.
NATURE COMMUNICATIONS (2019)
Nutrient Stress-Dysregulated Antisense lncRNA GLS-AS Impairs GLS-Mediated Metabolism and Represses Pancreatic Cancer Progression
Shi-Jiang Deng et al.
CANCER RESEARCH (2019)
AMP-activated protein kinase links acetyl-CoA homeostasis to BRD4 recruitment in acute myeloid leukemia
Yajian Jiang et al.
BLOOD (2019)
Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming
Marina Koutsioumpa et al.
GUT (2019)
The DNA methylation landscape in cancer
Ksenia Skvortsova et al.
DNA METHYLATION (2019)
The novel roles of circRNAs in human cancer
Qingfeng Shang et al.
MOLECULAR CANCER (2019)
Functions and mechanisms of non-histone protein acetylation
Takeo Narita et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer
Yun Wang et al.
MOLECULAR CANCER (2019)
Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis
Alessandro Carrer et al.
CANCER DISCOVERY (2019)
Epigenetic modifications of histones in cancer
Zibo Zhao et al.
GENOME BIOLOGY (2019)
CircHMGCS1 Promotes Hepatoblastoma Cell Proliferation by Regulating the IGF Signaling Pathway and Glutaminolysis
Ni Zhen et al.
THERANOSTICS (2019)
The DNA methyltransferase family: a versatile toolkit for epigenetic regulation
Frank Lyko
NATURE REVIEWS GENETICS (2018)
Glioma epigenetics: From subclassification to novel treatment options
Olga Gusyatiner et al.
SEMINARS IN CANCER BIOLOGY (2018)
R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling
Rui Su et al.
CELL (2018)
LncRNA-FEZFl-AS1 Promotes Tumor Proliferation and Metastasis in Colorectal Cancer by Regulating PKM2 Signaling
Zehua Bian et al.
CLINICAL CANCER RESEARCH (2018)
Pivotal role of NAMPT in the switch of melanoma cells toward an invasive and drug-resistant phenotype
Mickael Ohanna et al.
GENES & DEVELOPMENT (2018)
Novel insights on m6A RNA methylation in tumorigenesis: a double-edged sword
Shaoyun Wang et al.
MOLECULAR CANCER (2018)
Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
Jingjing Chen et al.
NATURE GENETICS (2018)
Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair
Parker L. Sulkowski et al.
NATURE GENETICS (2018)
Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer
Yonathan Lissanu Deribe et al.
NATURE MEDICINE (2018)
Cancer epigenetics: Moving forward
Angela Nebbioso et al.
PLOS GENETICS (2018)
Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells
Courtney L. Jones et al.
CANCER CELL (2018)
Beyond histone acetylation-writing and erasing histone acylations
Shuai Zhao et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2018)
Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia
Daniel A. Pollyea et al.
NATURE MEDICINE (2018)
Chromatin Succinylation Correlates with Active Gene Expression and Is Perturbed by Defective TCA Cycle Metabolism
John Smestad et al.
ISCIENCE (2018)
Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer
Sandeep Shelar et al.
CLINICAL CANCER RESEARCH (2018)
Non-coding RNA networks in cancer
Eleni Anastasiadou et al.
NATURE REVIEWS CANCER (2018)
Targeting chromatin defects in selected solid tumors based on oncogene addiction, synthetic lethality and epigenetic antagonism
D. Morel et al.
ANNALS OF ONCOLOGY (2017)
The role of fatty acid β-oxidation in lymphangiogenesis
Brian W. Wong et al.
NATURE (2017)
SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation
Xiaofeng Wang et al.
NATURE GENETICS (2017)
Cancer metabolism: a therapeutic perspective
Ubaldo E. Martinez-Outschoorn et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
From profiles to function in epigenomics
Stefan H. Stricker et al.
NATURE REVIEWS GENETICS (2017)
Metabolic regulation of gene expression through histone acylations
Benjamin R. Sabari et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
The epigenetic landscape of renal cancer
Mark R. Morris et al.
NATURE REVIEWS NEPHROLOGY (2017)
Glyceraldehyde-3-Phosphate Dehydrogenase Promotes Liver Tumorigenesis by Modulating Phosphoglycerate Dehydrogenase
Shanshan Liu et al.
HEPATOLOGY (2017)
Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity
Anthony T. Phan et al.
IMMUNITY (2017)
Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy
Xinjian Li et al.
MOLECULAR CELL (2017)
Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination
Sharanya Sivanand et al.
MOLECULAR CELL (2017)
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase
Yugang Wang et al.
NATURE (2017)
L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH
Andrew M. Intlekofer et al.
NATURE CHEMICAL BIOLOGY (2017)
Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
Oliver G. McDonald et al.
NATURE GENETICS (2017)
Marked for death: targeting epigenetic changes in cancer
Sophia Xiao Pfister et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Synthetic lethality and cancer
Nigel J. O'Neil et al.
NATURE REVIEWS GENETICS (2017)
TET-mediated active DNA demethylation: mechanism, function and beyond
Xiaoji Wu et al.
NATURE REVIEWS GENETICS (2017)
Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes
Cedric R. Clapier et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Metabolic inhibitors accentuate the anti-tumoral effect of HDAC5 inhibition
E. Hendrick et al.
ONCOGENE (2017)
Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC
Kiyotoshi Satoh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway
Xin Gu et al.
SCIENCE (2017)
Epigenetic plasticity and the hallmarks of cancer
William A. Flavahan et al.
SCIENCE (2017)
The cancer epigenome: Concepts, challenges, and therapeutic opportunities
Mark A. Dawson
SCIENCE (2017)
2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity
Parker L. Sulkowski et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine
Chantal Pauli et al.
CANCER DISCOVERY (2017)
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia
Alan H. Shih et al.
CANCER DISCOVERY (2017)
Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation
Vinay Bulusu et al.
CELL REPORTS (2017)
LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism
Xin Zheng et al.
EMBO JOURNAL (2017)
IDH Mutation, Competitive Inhibition of FTO, and RNA Methylation
Sara M. Elkashef et al.
CANCER CELL (2017)
Understanding the Intersections between Metabolism and Cancer Biology
Matthew G. Vander Heiden et al.
CELL (2017)
One-Carbon Metabolism in Health and Disease
Gregory S. Ducker et al.
CELL METABOLISM (2017)
Insulator dysfunction and oncogene activation in IDH mutant gliomas
William A. Flavahan et al.
NATURE (2016)
Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2
Satoshi Inoue et al.
CANCER CELL (2016)
Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes
Junjian Wang et al.
CANCER LETTERS (2016)
The Emerging Hallmarks of Cancer Metabolism
Natalya N. Pavlova et al.
CELL METABOLISM (2016)
α-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells
Tara TeSlaa et al.
CELL METABOLISM (2016)
Role of TET enzymes in DNA methylation, development, and cancer
Kasper Dindler Rasmussen et al.
GENES & DEVELOPMENT (2016)
Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells
Oliver D. K. Maddocks et al.
MOLECULAR CELL (2016)
Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2
Roxana S. Redis et al.
MOLECULAR CELL (2016)
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
Marco Sciacovelli et al.
NATURE (2016)
LKB1 loss links serine metabolism to DNA methylation and tumorigenesis
Filippos Kottakis et al.
NATURE (2016)
Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation
Min Pan et al.
NATURE CELL BIOLOGY (2016)
The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer
Aifu Lin et al.
NATURE CELL BIOLOGY (2016)
A network-biology perspective of microRNA function and dysfunction in cancer
Cameron P. Bracken et al.
NATURE REVIEWS GENETICS (2016)
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma
W. Marston Linehan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Circular RNA profile in gliomas revealed by identification tool UROBORUS
Xiaofeng Song et al.
NUCLEIC ACIDS RESEARCH (2016)
NON-CODING RNAs IN DEVELOPMENT AND DISEASE: BACKGROUND, MECHANISMS, AND THERAPEUTIC APPROACHES
Julia Beermann et al.
PHYSIOLOGICAL REVIEWS (2016)
Lateral Thinking: How Histone Modifications Regulate Gene Expression
Moyra Lawrence et al.
TRENDS IN GENETICS (2016)
Histone Modifications and Cancer
James E. Audia et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect (vol 5, 3608, 2014)
Paula Lopez-Serra et al.
NATURE COMMUNICATIONS (2016)
Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia
Xue Gao et al.
NATURE COMMUNICATIONS (2016)
The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation
Qiong Wu et al.
ONCOTARGET (2016)
KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism
Erhu Zhao et al.
CELL REPORTS (2016)
Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation
Eoin McDonnell et al.
CELL REPORTS (2016)
ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch
Steven Zhao et al.
CELL REPORTS (2016)
From Krebs to clinic: glutamine metabolism to cancer therapy
Brian J. Altman et al.
NATURE REVIEWS CANCER (2016)
Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
Zachary T. Schug et al.
CANCER CELL (2015)
The emerging roles of microRNAs in cancer metabolism
Brian Chan et al.
CANCER LETTERS (2015)
Lysine Demethylase LSD1 Coordinates Glycolytic and Mitochondrial Metabolism in Hepatocellular Carcinoma Cells
Akihisa Sakamoto et al.
CANCER RESEARCH (2015)
Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism
Samantha J. Mentch et al.
CELL METABOLISM (2015)
Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells
Arieh Moussaieff et al.
CELL METABOLISM (2015)
Hypoxia Induces Production of L-2-Hydroxyglutarate
Andrew M. Intlekofer et al.
CELL METABOLISM (2015)
Acetyl Coenzyme A: A Central Metabolite and Second Messenger
Federico Pietrocola et al.
CELL METABOLISM (2015)
NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
Carles Canto et al.
CELL METABOLISM (2015)
Hypoxia-Mediated Increases in L-2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress
William M. Oldham et al.
CELL METABOLISM (2015)
The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells
James G. Ryall et al.
CELL STEM CELL (2015)
Acetyl-CoA and the regulation of metabolism: mechanisms and consequences
Lei Shi et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
Long noncoding ribonucleic acid specific for distant metastasis of gastric cancer is associated with TRIM16 expression and facilitates tumor cell invasion in vitro
Yichao Yan et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2015)
NADP+-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance
Feng Li et al.
MOLECULAR CELL (2015)
Metabolic pathways promoting cancer cell survival and growth
Lindsey K. Boroughs et al.
NATURE CELL BIOLOGY (2015)
Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer
Sita Kugel et al.
CELL REPORTS (2015)
IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition
Andrew Kernytsky et al.
BLOOD (2015)
EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination
L. Gomez-Maldonado et al.
ONCOGENE (2015)
Serum miR-200c Is a Novel Prognostic and Metastasis-Predictive Biomarker in Patients With Colorectal Cancer
Yuji Toiyama et al.
ANNALS OF SURGERY (2014)
A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation
Gopinath Sutendra et al.
CELL (2014)
Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases
Tomoyuki Mashimo et al.
CELL (2014)
Acetate Dependence of Tumors
Sarah A. Comerford et al.
CELL (2014)
Methionine Metabolism Regulates Maintenance and Differentiation of Human Pluripotent Stem Cells
Nobuaki Shiraki et al.
CELL METABOLISM (2014)
Akt-Dependent Metabolic Reprogramming Regulates Tumor Cell Histone Acetylation
Joyce V. Lee et al.
CELL METABOLISM (2014)
Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation
Ariel A. Bazzini et al.
EMBO JOURNAL (2014)
Reciprocal Regulation of HIF-1 alpha and LincRNA-p21 Modulates the Warburg Effect
Fan Yang et al.
MOLECULAR CELL (2014)
Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
Supriya K. Saha et al.
NATURE (2014)
Lactate dehydrogenase A silencing in IDH mutant gliomas
Charles Chesnelong et al.
NEURO-ONCOLOGY (2014)
A long noncoding RNA connects c-Myc to tumor metabolism
Chiu-Lien Hung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The pentose phosphate pathway and cancer
Krushna C. Patra et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition
Ronen Marmorstein et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
Erasers of Histone Acetylation: The Histone Deacetylase Enzymes
Edward Seto et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
DNA Methylation in Mammals
En Li et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
L-2-Hydroxyglutarate: An Epigenetic Modifier and Putative Oncometabolite in Renal Cancer
Eun-Hee Shim et al.
CANCER DISCOVERY (2014)
SDH Mutations Establish a Hypermethylator Phenotype in Paraganglioma
Eric Letouze et al.
CANCER CELL (2013)
Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
Chenfang Dong et al.
CANCER CELL (2013)
The Histone H3 Methyltransferase G9A Epigenetically Activates the Serine-Glycine Synthesis Pathway to Sustain Cancer Cell Survival and Proliferation
Jane Ding et al.
CELL METABOLISM (2013)
Cellular Fatty Acid Metabolism and Cancer
Erin Currie et al.
CELL METABOLISM (2013)
Glutamine and cancer: cell biology, physiology, and clinical opportunities
Christopher T. Hensley et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Oncometabolites: linking altered metabolism with cancer
Ming Yang et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Circular RNAs are a large class of animal RNAs with regulatory potency
Sebastian Memczak et al.
NATURE (2013)
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
Olesya A. Ulanovskaya et al.
NATURE CHEMICAL BIOLOGY (2013)
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
Cigall Kadoch et al.
NATURE GENETICS (2013)
(R)-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
Julie-Aurore Losman et al.
SCIENCE (2013)
An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
Dan Rohle et al.
SCIENCE (2013)
Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation
Fang Wang et al.
SCIENCE (2013)
miRNAs link metabolic reprogramming to oncogenesis
Maria Hatziapostolou et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2013)
Tumour angiogenesis regulation by the miR-200 family
Chad V. Pecot et al.
NATURE COMMUNICATIONS (2013)
Succinate Dehydrogenase Mutation Underlies Global Epigenomic Divergence in Gastrointestinal Stromal Tumor
J. Keith Killian et al.
CANCER DISCOVERY (2013)
Serine, glycine and one-carbon units: cancer metabolism in full circle
Jason W. Locasale
NATURE REVIEWS CANCER (2013)
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
Patrick S. Ward et al.
CANCER CELL (2012)
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
Yoichiro Mitsuishi et al.
CANCER CELL (2012)
SnapShot: Histone Lysine Methylase Complexes
Man Mohan et al.
CELL (2012)
Cancer Epigenetics: From Mechanism to Therapy
Mark A. Dawson et al.
CELL (2012)
The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism
Carlos Sebastian et al.
CELL (2012)
Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
Haoqiang Ying et al.
CELL (2012)
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors
Mengtao Xiao et al.
GENES & DEVELOPMENT (2012)
IDH mutation impairs histone demethylation and results in a block to cell differentiation
Chao Lu et al.
NATURE (2012)
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
Sevin Turcan et al.
NATURE (2012)
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
Masato Sasaki et al.
NATURE (2012)
Histone methylation: a dynamic mark in health, disease and inheritance
Eric L. Greer et al.
NATURE REVIEWS GENETICS (2012)
S-ADENOSYLMETHIONINE IN LIVER HEALTH, INJURY, AND CANCER
Shelly C. Lu et al.
PHYSIOLOGICAL REVIEWS (2012)
Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
Wei Xu et al.
CANCER CELL (2011)
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
Nicholas T. Ingolia et al.
CELL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
Rasheduzzaman Chowdhury et al.
EMBO REPORTS (2011)
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
Ryan D. Morin et al.
NATURE (2011)
Initial genome sequencing and analysis of multiple myeloma
Michael A. Chapman et al.
NATURE (2011)
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
Yaoting Gui et al.
NATURE GENETICS (2011)
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
Kai Wang et al.
NATURE GENETICS (2011)
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
Manav Korpal et al.
NATURE MEDICINE (2011)
Harnessing synthetic lethal interactions in anticancer drug discovery
Denise A. Chan et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Developmental profile and regulation of the glycolytic enzyme hexokinase 2 in normal brain and glioblastoma multiforme
Amparo Wolf et al.
NEUROBIOLOGY OF DISEASE (2011)
A decade of exploring the cancer epigenome - biological and translational implications
Stephen B. Baylin et al.
NATURE REVIEWS CANCER (2011)
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
Patrick S. Ward et al.
CANCER CELL (2010)
Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
Maria E. Figueroa et al.
CANCER CELL (2010)
DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia
Maria E. Figueroa et al.
CANCER CELL (2010)
The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
Lei Zhong et al.
CELL (2010)
The widespread regulation of microRNA biogenesis, function and decay
Jacek Krol et al.
NATURE REVIEWS GENETICS (2010)
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
Sian Jones et al.
SCIENCE (2010)
The Biology of Chromatin Remodeling Complexes
Cedric R. Clapier et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Enzymes in the NAD+ Salvage Pathway Regulate SIRT1 Activity at Target Gene Promoters
Tong Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Lenny Dang et al.
NATURE (2009)
Long non-coding RNAs: insights into functions
Tim R. Mercer et al.
NATURE REVIEWS GENETICS (2009)
Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes
Ashby J. Morrison et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Glioma-Derived Mutations in IDH1 Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α
Shimin Zhao et al.
SCIENCE (2009)
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
Kathryn E. Wellen et al.
SCIENCE (2009)
Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death
Vivian Egler et al.
CLINICAL CANCER RESEARCH (2008)
The human Mi-2/NuRD complex and gene regulation
S. A. Denslow et al.
ONCOGENE (2007)
An essential switch in subunit composition of a chromatin remodeling complex during neural development
Julie Lessard et al.
NEURON (2007)
ISWI chromatin remodeling in ovarian somatic and germ cells:: revenge of the NURFs
David Pepin et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2007)
INO80 subfamily of chromatin remodeling complexes
Yunhe Bao et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2007)
The Chd family of chromatin remodelers
Concetta G. A. Marfella et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2007)
Dynamic regulation of histone lysine methylation by demethylases
Yang Shi et al.
MOLECULAR CELL (2007)
The multiple faces of caveolae
Robert G. Parton et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-2Oh2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats
Igor P. Pogribny et al.
CARCINOGENESIS (2006)
Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins
VP Tryndyak et al.
CANCER BIOLOGY & THERAPY (2006)
MicroRNAs - Critical regulators of development, cellular physiology and malignancy
JT Mendell
CELL CYCLE (2005)
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
HE Bryant et al.
NATURE (2005)
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
H Farmer et al.
NATURE (2005)
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
MF Fraga et al.
NATURE GENETICS (2005)
Micrornas: Small RNAs with a big role in gene regulation
L He et al.
NATURE REVIEWS GENETICS (2004)
Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer
E Ballestar et al.
EMBO JOURNAL (2003)
Glucose metabolism in cancer - Evidence that demethylation events play a role in activating type II hexokinase gene expression
A Goel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
分享论文
