The global prevalence of Spirometra parasites in snakes, frogs, dogs, and cats: A systematic review and meta-analysis

Background: Spirometra infection is aneglected food- and waterborne disease with worldwide distribution. Objectives: The present study aims to estimate the global prevalence of Spirometra species in snakes, frogs, dogs and cats. Methods: Multiple databases (PubMed, Scopus, ProQuest, Web of Science and Google Scholar) were searched for relevant literatures published up to March 2022. Results: Among 131 data sets (including 113 articles) that met the inclusion, 15 investigations reported Spirometra infection in snakes, 23 in frogs, 41 in dogs and 52 in cats. The pooled prevalence (95% confidence interval) in intermediate hosts and definitive hosts was found to be 0.313% and 0.089%, respectively. Based on continent, the infection was most prevalent in Asia for studies on snakes (0.696%) and frogs (0.181%), while Africa (0.224%) and Oceania (0.203%) were the regions with the highest pooled prevalence rates of the infection in dogs and cats, respectively. Among different diagnostic methods, the highest pooled prevalence was related to morphological method for studies on snakes, frog and cats with rate of 0.665%, 0.189% and 0.104%, respectively. Regarding studies on dogs, the highest pooled prevalence was observed for molecular technique (0.101%). Conclusions: The results presented here revealed the importance of establishing a prevention and control measure focused on protection of aquaculture systems from being contaminated with faeces of dogs and cats, and raising awareness of parasitic zoonotic diseases to decrease the transmission risk.

Automated summary

This study aimed to estimate the global prevalence of Spirometra species in snakes, frogs, dogs, and cats. The results showed that the pooled prevalence of infection in intermediate hosts and definitive hosts was 0.313% and 0.089%, respectively. The highest prevalence rates in snakes and frogs were found in Asia, while Africa and Oceania had the highest prevalence rates in dogs and cats, respectively. Morphological method had the highest prevalence rate in studies on snakes, frogs, and cats, while molecular technique had the highest prevalence rate in studies on dogs.