Comparison of epidemiological characteristics and transmissibility of different strains of COVID-19 based on the incidence data of all local outbreaks in China as of March 1, 2022

Article Infectious Diseases

Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021

Jantlen A. Backer et al.

Summary: The SARS- CoV-2 Omicron variant has a growth advantage over the Delta variant due to higher transmissibility, immune evasion, or a shorter serial interval.

EUROSURVEILLANCE (2022)

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Article Immunology

Transmission Dynamics of the Delta Variant of SARS-CoV-2 Infections in South Korea

Hari Hwang et al.

Summary: The Delta variant is highly transmissible in indoor settings and households. Measures such as rapid contact tracing, isolation of asymptomatic contacts, adherence to public health measures, and increased COVID-19 vaccination, including booster doses, are needed to reduce community transmission of the Delta variant.

JOURNAL OF INFECTIOUS DISEASES (2022)

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Editorial Material Infectious Diseases

What is the vaccine effect on reducing transmission in the context of the SARS-CoV-2 delta variant?

Annelies Wilder-Smith

LANCET INFECTIOUS DISEASES (2022)

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Article Infectious Diseases

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study

Anika Singanayagam et al.

Summary: Vaccination reduces the risk of delta variant infection and accelerates viral clearance. However, fully vaccinated individuals with breakthrough infections may still have similar peak viral loads as unvaccinated cases and can efficiently transmit the infection.

LANCET INFECTIOUS DISEASES (2022)

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Article Infectious Diseases

Transmission and containment of the SARS-CoV-2 Delta variant of concern in Guangzhou, China: A population-based study

Li Li et al.

Summary: This study describes the community transmission of the Delta variant in Guangzhou, China and evaluates the containment measures implemented during this outbreak. The results show that the hierarchical prevention and control strategy in Guangzhou was timely and effective, and vaccination played a positive role in reducing disease symptoms.

PLOS NEGLECTED TROPICAL DISEASES (2022)

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News Item Critical Care Medicine

Omicron variant and booster COVID-19 vaccines

Talha Khan Burki

LANCET RESPIRATORY MEDICINE (2022)

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Article Medicine, General & Internal

Relative Reproduction Number of SARS-CoV-2 Omicron (B.1.1.529) Compared with Delta Variant in South Africa

Hiroshi Nishiura et al.

JOURNAL OF CLINICAL MEDICINE (2022)

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Article Immunology

Variants of Concern Are Overrepresented Among Postvaccination Breakthrough Infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Washington State

Abbye E. McEwen et al.

Summary: Among 20 vaccine breakthrough cases at the institution, all infections were caused by variants of concern, with a median Ct value of 20.2. Variants of concern were significantly more prevalent in breakthrough infections compared to contemporaneous samples sequenced in the laboratory.

CLINICAL INFECTIOUS DISEASES (2022)

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Letter Immunology

Serial Intervals and Household Transmission of SARS-CoV-2 Omicron Variant, South Korea, 2021

Jin Su Song et al.

Summary: To understand the transmissibility of the Omicron variant of SARS-CoV-2, this study investigated the serial intervals and secondary attack rates among household contacts in South Korea. The findings showed a mean serial interval of 2.9 days for transmission pairs and a secondary attack rate of 50.0% among 25 households, raising concerns about a rapid increase in cases.

EMERGING INFECTIOUS DISEASES (2022)

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Article Immunology

Serial Interval and Transmission Dynamics during SARS-CoV-2 Delta Variant Predominance, South Korea

Sukhyun Ryu et al.

Summary: We estimated the mean serial interval and superspreading potential of the Delta variant in South Korea. The intervals were similar during two different study periods, as were the proportions of cases responsible for the majority of transmissions.

EMERGING INFECTIOUS DISEASES (2022)

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Article Biology

Estimation of incubation period and generation time based on observed length-biased epidemic cohort with censoring for COVID-19 outbreak in China

Yuhao Deng et al.

Summary: This study focused on the analysis of the incubation period and generation time, proposing a consistent estimator for the distribution of generation time based on the incubation period and serial interval, suitable for incubation-infectious diseases. The real case application to COVID-19 outbreak revealed a median incubation period of 8.50 days and an estimated basic reproduction number of 2.96 in the early phase.

BIOMETRICS (2021)

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Article Infectious Diseases

Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69-V70, France, August to December 2020

Antonin Bal et al.

Summary: The study reported the strategy leading to the first detection of the variant of concern 202012/01 (VOC) in France, by screening for mutations such as Delta H69/Delta V70 associated with VOC and identifying co-occurring mutations like S:N501Y.

EUROSURVEILLANCE (2021)

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Editorial Material Otorhinolaryngology

COVID-19 Vaccines May Not Prevent Nasal SARS-CoV-2 Infection and Asymptomatic Transmission

Benjamin S. Bleier et al.

Summary: Current COVID-19 vaccine candidates, administered by injection to produce an IgG response, may not fully prevent viral shedding in the nasal cavity, potentially allowing transmission. Otolaryngology providers should continue taking precautions to protect vulnerable patients until further knowledge on mucosal immunity post-systemic vaccination is acquired.

OTOLARYNGOLOGY-HEAD AND NECK SURGERY (2021)

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Letter Infectious Diseases

The Delta SARS-CoV-2 variant has a higher viral load than the Beta and the historical variants in nasopharyngeal samples from newly diagnosed COVID-19 patients

Elisa Teyssou et al.

JOURNAL OF INFECTION (2021)

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Review Infectious Diseases

Serial interval and incubation period of COVID-19: a systematic review and meta-analysis

Muluneh Alene et al.

Summary: This study aimed to determine the overall average serial interval and incubation period of COVID-19 by combining findings of existing studies. The weighted pooled mean serial interval of COVID-19 was found to be 5.2 days and the mean incubation period was 6.5 days. The study suggests that presymptomatic transmission may account for a significant number of COVID-19 cases, as the average serial interval is shorter than the average incubation period.

BMC INFECTIOUS DISEASES (2021)

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Editorial Material Medicine, General & Internal

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic

Salim S. Abdool Karim et al.

LANCET (2021)

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Article Infectious Diseases

Novel SARS-CoV-2 variants: the pandemics within the pandemic

Erik Boehm et al.

Summary: Many new variants of SARS-CoV-2 have been identified as variants of concern/interest due to increased transmissibility, severity, immune escape, and reduced vaccine efficacy. These variants often share similar mutations, such as N501Y and E484K, which lead to partial immune escape, decreased vaccine efficacy, and potentially increased severity.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

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Editorial Material Oncology

The omicron variant of SARS-CoV-2: Understanding the known and living with unknowns COMMENT

Nicholas E. Ingraham et al.

Summary: The recently discovered Omicron variant of SARS-CoV-2 has raised global concern due to its more than 50 mutations and potential impact on public health. Current knowledge about this viral variant is limited, and there is a need to rapidly address key questions surrounding it.

CLINICAL AND TRANSLATIONAL MEDICINE (2021)

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Article Public, Environmental & Occupational Health

Linked Clusters of SARS-CoV-2 Variant B.1.351-Maryland, January-February 2021

Kenneth A. Feder et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

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Article Infectious Diseases

Rapid spread of the SARS-CoV-2 Delta variant in some French regions, June 2021

Samuel Alizon et al.

Summary: The study found rapid growth of the Delta variant in three metropolitan regions of France, with an estimated transmission advantage of +79% compared with the Alpha variant. The coming weeks will be crucial, as the magnitude of the estimated transmission advantage of the Delta variant could pose a major challenge for public health authorities.

EUROSURVEILLANCE (2021)

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Editorial Material Public, Environmental & Occupational Health

The reproductive number of the Delta variant of SARS-CoV-2 is far higher compared to the ancestral SARS-CoV-2 virus

Ying Liu et al.

Summary: The Delta variant is rapidly replacing other strains of SARS-CoV-2, with a higher R-0 value of 5.08 compared to the ancestral strain's 2.79. Increasing vaccine coverage and strengthening public health measures are now more urgent than ever to control the spread of the virus.

JOURNAL OF TRAVEL MEDICINE (2021)

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Letter Medicine, General & Internal

Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination

Emma C. Wall et al.

LANCET (2021)

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Article Multidisciplinary Sciences

Emergence and expansion ofSARS-CoV-2 B.1.526 after identification in New York

Medini K. Annavajhala et al.

Summary: The emergence of the B.1.526 lineage of SARS-CoV-2, with mutations such as E484K, has led to its rapid dominance in New York City. This variant is resistant to therapeutic monoclonal antibodies and less susceptible to neutralization by antibodies from recovered or vaccinated individuals, contributing to its fast spread.

NATURE (2021)

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News Item Medicine, General & Internal

Covid-19: Are high rates of B.1.617.2 linked to vaccine hesitancy?

Gareth Iacobucci

BMJ-BRITISH MEDICAL JOURNAL (2021)

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News Item Critical Care Medicine

Lifting of COVID-19 restrictions in the UK and the Delta variant

Talha Khan Burki

LANCET RESPIRATORY MEDICINE (2021)

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Article Public, Environmental & Occupational Health

Diagnostic performance of rapid antigen test for COVID-19 and the effect of viral load, sampling time, subject's clinical and laboratory parameters on test accuracy

Rania M. Amer et al.

Summary: The study found that the rapid antigen test RAT (StandardTM Q COVID-19 Ag) has lower diagnostic performance compared to reverse transcriptase quantitative real-time PCR (RT-qPCR) for COVID-19 diagnosis and should not be used alone for diagnosis. RAT is best used at the early disease stage and in patients with high viral load.

JOURNAL OF INFECTION AND PUBLIC HEALTH (2021)

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Article Medicine, General & Internal

Importation and Transmission of SARS-CoV-2 B.1.1.529 (Omicron) Variant of Concern in Korea, November 2021

Ji Joo Lee et al.

Summary: The omicron VOC has shown community transmission in South Korea, and there may be more unreported transmissions related to this variant.

JOURNAL OF KOREAN MEDICAL SCIENCE (2021)

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Article Mathematical & Computational Biology

Quantifying competitive advantages of mutant strains in a population involving importation and mass vaccination rollout

Fan Xia et al.

Summary: This article introduces the spread of the SARS-CoV-2 Delta variant in multiple countries and proposes a method to simulate the invasion process and estimate the competitive advantage of the variant. Research results show that the Delta variant has a higher transmission capacity than other strains, which helps explain the resurgence of the epidemic in many countries, even those with relatively high vaccination rates.

INFECTIOUS DISEASE MODELLING (2021)

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Article Medicine, General & Internal

Transmission, viral kinetics and clinical characteristics of the emergent SARS-CoV-2 Delta VOC in Guangzhou, China

Yaping Wang et al.

Summary: Infection with the Delta variant of concern (VOC) is characterized by a shorter incubation period, higher viral load, and longer duration of viral shedding, with an increased risk of critical illness for patients over the age of 60, calling for more intensive prevention and control measures.

ECLINICALMEDICINE (2021)

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Article Public, Environmental & Occupational Health

Modelling the Emerging COVID-19 Epidemic and Estimating Intervention Effectiveness - Taiwan, China, 2021

Weikang Liu et al.

Summary: This study aimed to calculate the transmissibility of COVID-19 in Taiwan, China and predict the trends, as well as evaluate the effects of interventions. Results showed that even with the most effective interventions, the COVID-19 epidemic was projected to last for at least one more month in Taiwan, China.

CHINA CDC WEEKLY (2021)

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Letter Public, Environmental & Occupational Health