相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Biophysical investigation of the dual binding surfaces of human transcription factors FOXO4 and p53
Jinwoo Kim et al.
FEBS JOURNAL (2022)
FOXO4 interacts with p53 TAD and CRD and inhibits its binding to DNA
Raju Mandal et al.
PROTEIN SCIENCE (2022)
Drugging the 'undruggable'. Therapeutic targeting of protein-DNA interactions with the use of computer-aided drug discovery methods
Mariia Radaeva et al.
DRUG DISCOVERY TODAY (2021)
Structural Biology in the Clouds: The WeNMR-EOSC Ecosystem
Rodrigo Honorato et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2021)
A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma
Stefan Salcher et al.
ONCOGENE (2020)
Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics
Katarina Psenakova et al.
CELLS (2019)
Modulating FOXO3 transcriptional activity by small, DBD-binding molecules
Judith Hagenbuchner et al.
ELIFE (2019)
Targeting transcription factors in cancer - from undruggable to reality
John H. Bushweller
NATURE REVIEWS CANCER (2019)
C100RF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy
S. Salcher et al.
MOLECULAR CANCER (2017)
FOXO3-mediated chemo-protection in high-stage neuroblastoma depends on wild-type TP53 and SESN3
M. Rupp et al.
ONCOGENE (2017)
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
Marjolein P. Baar et al.
CELL (2017)
The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes
G. C. P. van Zundert et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma
Judith Hagenbuchner et al.
Oncotarget (2016)
NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy
Woonghee Lee et al.
BIOINFORMATICS (2015)
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors
Paola Infante et al.
EMBO JOURNAL (2015)
A Small Molecule Compound Targeting STAT3 DNA-Binding Domain Inhibits Cancer Cell Proliferation, Migration, and Invasion
Wei Huang et al.
ACS CHEMICAL BIOLOGY (2014)
Discovery of Small-Molecule Inhibitors Selectively Targeting the DNA-Binding Domain of the Human Androgen Receptor
Huifang Li et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma
Stefan Salcher et al.
MOLECULAR CANCER (2014)
Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition
Michael V. Gormally et al.
NATURE COMMUNICATIONS (2014)
Using chemical shift perturbation to characterise ligand binding
Mike P. Williamson
PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY (2013)
Forkhead box proteins: tuning forks for transcriptional harmony
Eric W. -F. Lam et al.
NATURE REVIEWS CANCER (2013)
Foxo3a drives proliferation in anaplastic thyroid carcinoma through transcriptional regulation of cyclin A1: a paradigm shift that impacts current therapeutic strategies
Laura A. Marlow et al.
JOURNAL OF CELL SCIENCE (2012)
Forkhead Box O as a Sensor, Mediator, and Regulator of Redox Signaling
Peter L. J. de Keizer et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
FOXO and FOXM1 in Cancer: The FOXO-FOXM1 Axis Shapes the Outcome of Cancer Chemotherapy
Miranda S.C. Wilson et al.
CURRENT DRUG TARGETS (2011)
Foxo Transcription Factors Control Regulatory T Cell Development and Function
Yann M. Kerdiles et al.
IMMUNITY (2010)
Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells
Yohsuke Harada et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
TGF-β-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia
Kazuhito Naka et al.
NATURE (2010)
Biochemical and Structural Characterization of an Intramolecular Interaction in FOXO3a and Its Binding with p53
Feng Wang et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification
Kuang-Lei Tsai et al.
NUCLEIC ACIDS RESEARCH (2007)
Druggability indices for protein targets derived from NMR-based screening data
PJ Hajduk et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Multiple elements regulate nuclear/cytoplasmic shuttling of FOX01: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms
XS Zhao et al.
BIOCHEMICAL JOURNAL (2004)
Synthesis and structure activity relationship of guanidines as NPYY5 antagonists
CJ Aquino et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2004)
Two 14-3-3 binding motifs are required for stable association of forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding
T Obsil et al.
BIOCHEMISTRY (2003)
Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse
WH Biggs et al.
MAMMALIAN GENOME (2001)
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
CM Cahill et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
分享论文
