期刊
BRAIN SCIENCES
卷 12, 期 10, 页码 -出版社
MDPI
DOI: 10.3390/brainsci12101407
关键词
bipolar disorder; bipolar depression; Behavioural Activation; psychological therapy
This study investigated the feasibility and acceptability of an adapted version of Behavioral Activation (BA) for bipolar depression in a UK outpatient sample. The results showed high retention in therapy, with participants reporting satisfaction with the intervention. No therapy-related serious adverse events or exacerbations in manic symptoms were reported. The pattern of change on outcome measures suggests potential clinical benefit. Therefore, adapted BA for bipolar depression is a feasible and acceptable approach that merits further investigation.
Behavioural Activation (BA) is associated with a substantial evidence base for treatment of acute unipolar depression, and has promise as an easily disseminable psychological intervention for bipolar depression. Using a randomised multiple baseline case series design we examined the feasibility and acceptability of an adapted version of BA in a U.K. outpatient sample of 12 adults with acute bipolar depression. Participants were allocated at random to a 3-8 week wait period before being offered up to 20 sessions of BA. They completed outcome measures at intake, pre- and post-treatment and weekly symptom measures across the study period. Retention in therapy was high (11/12 participants completed the target minimum number of sessions), and all participants returning acceptability measures reported high levels of satisfaction with the intervention. No therapy-related serious adverse events were reported, nor were there exacerbations in manic symptoms that were judged to be a result of the intervention. The pattern of change on outcome measures is consistent with the potential for clinical benefit; six of the nine participants with a stable baseline showed clinically significant improvement on the primary outcome measure. The findings suggest adapted BA for bipolar depression is a feasible and acceptable approach that merits further investigation.
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